Collect. Czech. Chem. Commun.
1979, 44, 976-980
https://doi.org/10.1135/cccc19790976
Synthesis of 8-azidoadenosine 5'-phosphate
Josef Houštěka and Jiří Smrtb
a Physiological Institute, Czechoslovak Academy of Sciences, 142 00 Prague 4
b Institute of Organic Chemistry and Biochemistry, Czechoslovak Academy of Sciences, 166 10 Prague 6
Abstract
Sodium azide reacts with 8-bromoadenosine 5'-phosphate (I) in dimethyl sulfoxide under the formation of 8-azidoadenosine 5'-phosphate (II). The compound II was prepared alternatively from 8-azidoadenosine (V) and phosphoryl chloride.
