Collect. Czech. Chem. Commun.
1980, 45, 901-905
https://doi.org/10.1135/cccc19800901
Esters of 1-p-chlorobenzoyl-5-methoxy-2-methyl-3-indolylacetic acid
Ludmila Fišnerová, Vlastimil Rábek and Oldřich Němeček
Research Institute for Pharmacy and Biochemistry, 130 63 Prague 3
Abstract
Reactions of imidazolide of 1-p-chlorobenzoyl-5-methoxy-2-methyl-3-indolylacetic acid, prepared from the acid and N,N'-carbonyldiimidazole, with the optically active forms of 2-phenyl-3-hydroxypropane acid and with the inactive forms of p-chloro-, p-isopropyl-, and p-isobutyl-2-phenyl-3-hydroxypropane acids gave the corresponding esters. The compounds were tested for antiinflammatory activity.
