Collect. Czech. Chem. Commun.
1981, 46, 262-265
https://doi.org/10.1135/cccc19810262
Reduction of 1-isoquinolyl-dimethylmethanol and 1-(1-isoquinolyl)cyclohexanol
Miloslav Ferles, Michaela Šputová and Marian Tegza
Department of Organic Chemistry, Prague Institute of Chemical Technology, 166 28 Prague 6
Abstract
Reduction of alcohols Ia and IIa with zinc and formic acid afforded 1-isopropylisoquinoline (Ib) and 1-cyclohexylisoquinoline (IIb), respectively, reduction with sodium in 1-butanol led to the 1,2,3,4-tetrahydroisoquinoline derivatives III, IV and Va and electrolytical reduction gave 1-isopropyl-1,2,3,4-tetrahydroisoquinoline (Vd) and the 1-cyclohexyl derivative Ve, respectively.
