Collect. Czech. Chem. Commun.
1981, 46, 446-451
https://doi.org/10.1135/cccc19810446
A modified route to intermediates in partial syntheses of digitoxigenin and xysmalogenin
Pavel Kočovský and Václav Černý
Institute of Organic Chemistry and Biochemistry, Czechoslovak Academy of Sciences, 166 10 Prague 6
Abstract
3β-Hydroxy-5,14-pregnadien-20-one (X) was prepared via 6β-methoxy-3α,5-cyclo-5α-pregn-14-en-20-one (VII). The compound X and its acetate XI are known intermediates in partial syntheses of digitoxigenin and xysmalogenin, respectively. In the present paper, conversion of X into the cardenolide XVII is also described.
