Collect. Czech. Chem. Commun.
1981, 46, 1976-1982
https://doi.org/10.1135/cccc19811976
Syntheses of 17β-(2-maleimido)androstanes
Pavel Drašar and Miroslav Havel
Institute of Organic Chemistry and Biochemistry, Czechoslovak Academy of Sciences, 166 10 Prague 6
Abstract
Starting from pregnane derivatives, 17β-(2-maleimido)androstanes of 5α- and Δ5-series, with and without a 3β-acetoxy group, were prepared via methyl 3-androstanyl-3-cyano acrylates. The maleimidoandrostanes were synthesized as models of cardiotonic steroids.