Collect. Czech. Chem. Commun.
1981, 46, 2263-2267
https://doi.org/10.1135/cccc19812263
Resolution of S-benzyl-DL-penicillamine with penicillin amidohydrolase
Petr Šimeka, Tomislav Bartha, Miroslav Bártab, Vladimír Vojtíšekb and Karel Jošta
a Institute of Organic Chemistry and Biochemistry, Czechoslovak Academy of Sciences, 166 10 Prague 6
b Research Institute of Antibiotics and Biotransformations, 252 63 Roztoky
Abstract
Racemic m-phenylacetyl-S-benzylpenicillamine was resolved into otical isomers by action of penicillin amidohydrolase (E.C.3.5.1.11) in high yield and optical purity.
