Collect. Czech. Chem. Commun. 1982, 47, 1641-1644
https://doi.org/10.1135/cccc19821641

1,2-Fused derivatives of ergoline

Jan Beneš and Jiří Holubek

Research Institute for Pharmacy and Biochemistry, 130 60 Prague 3

Abstract

2-Formylergoline derivatives I and II were condensed with methyl isonitrilacetate in the presence of a base. Depending on the nature of this base, the main products of the reaction were either derivatives of pyrimido[1,6-a]ergoline, III and IV, or derivatives of 2-formylamino-3-oxo-3H-pyrrolo[1,2-a]ergoline, V and VI.