Collect. Czech. Chem. Commun.
1983, 48, 1077-1088
https://doi.org/10.1135/cccc19831077
The effects of lipophilicity on the inhibition of denaturation of serum albumin and on the activation of fibrinolysis observed with a series of benzyloxyarylaliphatic acids
Miroslav Kuchař, Václav Rejholec, Zdeněk Roubal and Oluše Matoušová
Research Institute for Pharmacy and Biochemistry, 130 60 Prague 3
Individual author index pages
Other CCCC articles of these authors
- Václav Kozmík, Bedřich Košata, Jiří Svoboda* and Miroslav Kuchař
A Study of 5-Nitroindole Alkylation
2006, Vol. 71, Issue 5, pp. 679–690 [Abstract] - Miroslav Kuchař*, Bohumila Brunová, Richard Junek, Robert Rodling, Josef Hájíček, Vladimíra Panajotová and Antonín Jandera
The Antileukotrienic Derivatives and Homologues of [(Quinolin-2-ylmethoxy)sulfanyl]benzoic Acids with Reduced Lipophilicity
2005, Vol. 70, Issue 9, pp. 1357–1371 [Abstract] - Miroslav Kuchař*, Vojtěch Kmoníček, Vladimíra Panajotová, Antonín Jandera, Bohumila Brunová, Richard Junek, Věra Bucharová, Jan Čejka and Dalibor Šatinský
Derivatives of (Phenylsulfanyl)benzoic Acids with Multiple Antileukotrienic Activity
2004, Vol. 69, Issue 11, pp. 2098–2120 [Abstract] - Vladimír Wsól*, Barbora Szotáková, Vendula Baliharová, Luděk Šišpera, Michal Holčapek, Lenka Kolářová, Bohumila Suchanová, Miroslav Kuchař and Lenka Skálová
The Phase I Biotransformation of the Potential Antileukotrienic Drug Quinlukast in Rat Microsomes and Hepatocytes
2004, Vol. 69, Issue 3, pp. 689–702 [Abstract] - Jiří Svoboda*, Michal Štádler, Antonín Jandera, Vladimíra Panajotová and Miroslav Kuchař
Synthesis and Biological Evaluation of New Antiinflammatory 1-Benzothiophene-2-carboxanilides
2000, Vol. 65, Issue 7, pp. 1082–1092 [Abstract] - Miroslav Kuchař, Kateřina Čulíková, Vladimíra Panajotovová, Bohumila Brunová, Antonín Jandera and Vojtěch Kmoníček
2,4-Dihydroxyacetophenone Derivatives as Antileukotrienics with a Multiple Activity Mechanism
1998, Vol. 63, Issue 1, pp. 103–114 [Abstract] - Miroslav Kuchař, Marie Poppová, Antonín Jandera, Vladimíra Panajotovová, Hana Zůnová, Miloš Buděšínský, Hana Tomková, Alexandr Jegorov and Jan Taimr
Chiral Forms of 4-(2',4'-Difluorobiphenyl-4-yl)-2-methyl-4-oxobutanoic Acid (Flobufen) and Its Metabolite.Synthesis and Basic Biological Properties
1997, Vol. 62, Issue 3, pp. 498–509 [Abstract] - Miroslav Kuchař, Václav Vosátka, Marie Poppová, Eva Knězová, Vladimíra Panajotovová, Hana Tomková and Jan Taimr
Some Analogs of 4-(2',4'-Difluorobiphenyl-4-yl)-2-methyl-4-oxobutanoic Acid: Synthesis and Antiinflammatory Activity
1995, Vol. 60, Issue 6, pp. 1026–1033 [Abstract] - Miroslav Kuchař, Marie Poppová, Hana Zůnová, Eva Knězová, Václav Vosátka and Marek Příhoda
4-(2',4'-Difluorobiphenyl-4-yl)-2-methyl-4-oxobutanoic Acid and Its Derivatives
1994, Vol. 59, Issue 12, pp. 2705–2713 [Abstract] - Bohdan Schneider, Karel Huml and Václav Rejholec
Three-dimensional structures of substituted benzylphenyl ethers
1991, Vol. 56, Issue 10, pp. 2188–2198 [Abstract] - Bohdan Schneider, Václav Rejholec and Miroslav Kuchař
Three-dimensional structures of substituted diphenyl sulfides
1990, Vol. 55, Issue 11, pp. 2590–2601 [Abstract] - Vladimír Valenta, Jiří Holubek, Emil Svátek, Oluše Matoušová, Jiřina Metyšová and Miroslav Protiva
Potential neuroleptics of the orthopramide series; synthesis of heterocyclic 5-amino-2-methoxybenzamides and of some related compounds
1990, Vol. 55, Issue 5, pp. 1297–1310 [Abstract] - Miloš Beran, Antonín Černý, Miroslav Kuchař, Hana Adamírová, Jiří Holubek, Jan Taimr, Jaroslav Vachek, Maria Frühaufová, Karel Řežábek, Martin Valchář and Ivan Krejčí
9,10-Dihydroergopeptines modified in position 6
1990, Vol. 55, Issue 3, pp. 819–832 [Abstract] - Miroslav Kuchař, Jaroslava Grimová, Václav Rejholec, Hana Tomková, Magda Jelínková and Jiří Holubek
Use of QSAR in design of antiinflammatory fluorinated arylalkanoic acids
1990, Vol. 55, Issue 1, pp. 296–306 [Abstract] - Karel Šindelář, Vladimír Valenta, Jiří Holubek, Oluše Matoušová and Miroslav Protiva
Potential antidepressants. Synthesis of 6,11-dihydrodibenzo[b,e]thiepin-11-yl (dimethylaminomethyl)phenyl ethers, sulfides, amines and some related compounds
1990, Vol. 55, Issue 1, pp. 282–295 [Abstract] - Zdeněk Polívka, Miloš Buděšínský, Jiří Holubek, Bohdan Schneider, Zdeněk Šedivý, Emil Svátek, Oluše Matoušová, Jan Metyš, Martin Valchář, Radomír Souček and Miroslav Protiva
4H-Benzo[4,5]cyclohepta[1,2-b]thiophenes and 9,10-dihydro derivatives - Sulfonium analogues of pizotifen and ketotifen; Chirality of ketotifen; Synthesis of the 2-bromo derivative of ketotifen
1989, Vol. 54, Issue 9, pp. 2443–2469 [Abstract] - Jiří Jílek, Jiří Urban, Vojtěch Kmoníček, Josef Pomykáček, Jiří Holubek, Emil Svátek, Oluše Matoušová, Jan Metyš, Martin Valchář, Stanislav Wildt and Miroslav Protiva
Potential anticonvulsants: 3-Chlorobenzophenone derivatives
1989, Vol. 54, Issue 8, pp. 2248–2260 [Abstract] - Karel Šindelář, Marta Hrubantová, Emil Svátek, Oluše Matoušová, Jiřina Metyšová, Martin Valchář and Miroslav Protiva
Potential antidepressants: 4-(Thioaryloxy)piperidines
1989, Vol. 54, Issue 8, pp. 2240–2247 [Abstract] - Hana Hulinská, Miloš Buděšínský, Jiří Holubek, Oluše Matoušová, Hana Frycová and Miroslav Protiva
Reactions of N-substituted 2-aminopyridines with chloroacetyl chloride; Formation of a new series of heterocyclic betaines: 1-Substituted 4-chloromethyl-2-oxopyrido[1,2-a]pyrimidin-5-ium-3-olates
1989, Vol. 54, Issue 5, pp. 1376–1387 [Abstract] - Jiří Jílek, Martin Valchář, Jiří Holubek, Nataša Dlohožková, Josef Pomykáček, Oluše Matoušová, Jiřina Metyšová and Miroslav Protiva
Noncataleptic neuroleptic agents: 2-(4-(2-(2-Chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yloxy)ethyl)piperazine-1-yl)ethanol and some related compounds
1988, Vol. 53, Issue 11, pp. 2731–2741 [Abstract] - Miroslav Kuchař, Eva Maturová, Bohumila Brunová, Jaroslava Grimová, Hana Tomková and Jiří Holubek
Quantitative relations between structure and antiinflammatory activity of aryloxoalkanoic acids
1988, Vol. 53, Issue 8, pp. 1862–1872 [Abstract] - Hana Hulinská, Zdeněk Polívka, Jiří Jílek, Karel Šindelář, Jiří Holubek, Emil Svátek, Oluše Matoušová, Miloš Buděšínský, Hana Frycová and Miroslav Protiva
Experimental antiulcer agents: N-substituted 2-(4-methyl-1-piperazinyl)acetamides as pirenzepine models and some related compounds
1988, Vol. 53, Issue 8, pp. 1820–1844 [Abstract] - Karel Šindelář, Jiří Holubek, Oluše Matoušová, Emil Svátek, Martin Valchář, Antonín Dlabač, Nataša Dlohožková, Marta Hrubantová and Miroslav Protiva
Aminoalkylidene and aminoalkyl derivatives of 6,11-dihydrodibenzo[b,e]thiepin-2- and -9-carbonitrile and 4,10-dihydrothieno[2,3-c]-1-benzothiepin-6-carbonitrile; Antidepressants with a new activity profile
1988, Vol. 53, Issue 2, pp. 340–360 [Abstract] - Zdeněk Vejdělek, Jan Metyš, Jiří Holubek, Miloš Buděšínský, Emil Svátek, Oluše Matoušová and Miroslav Protiva
Potentional anxiolytics and hypnotics: 1-(Alkanesulfonamidoalkyl)-6-aryl-8-halogeno-s-triazolo[4,3-a]-1,4-benzodiazepines and related compounds
1988, Vol. 53, Issue 1, pp. 132–144 [Abstract] - Zdeněk Polívka, Jiří Holubek, Miloš Buděšínský, Oluše Matoušová, Emil Svátek, Jan Metyš and Miroslav Protiva
Potential antihistamine agents: 4-(6,11-Dihydrodibenzo[b,e]thiepin-11-ylidene)-1-methyltetrahydrothiopyranium iodide and similar sulfonium salts derived from related tricyclic systems
1987, Vol. 52, Issue 11, pp. 2758–2774 [Abstract] - Karel Šindelář, Miloš Buděšínský, Tomáš Vaněk, Jiří Holubek, Emil Svátek, Oluše Matoušová, Charles Wayne Rees and Miroslav Protiva
Reaction of 6,11-dihydrodibenzo[b,e]thiepin-11-carbonitrile with 1,2-dibromoethane, a reinvestigation. Formation of 11,12-dihydro-6H-6,12-methanodibenzo[b,f]thiocin-12-carbonitrile
1987, Vol. 52, Issue 9, pp. 2281–2294 [Abstract] - Miroslav Kuchař, Bohumila Brunová, Jaroslava Grimová, Stanislav Vaněček and Jiří Holubek
Synthesis of cyclohexylaliphatic acids and their pharmacological properties
1986, Vol. 51, Issue 12, pp. 2896–2908 [Abstract] - Miroslav Kuchař, Bohumila Brunová, Jaroslava Grimová, Václav Rejholec and Václav Čepelák
On the quantitative relations between structure and antiaggregation activity of ω-aryl-ω-oxoalkanoic acids
1986, Vol. 51, Issue 11, pp. 2617–2625 [Abstract] - Miroslav Kuchař, Bohumila Brunová, Václav Rejholc, Magda Jelínková, Jiří Holubek and Oldřich Němeček
Quantitative relations between structure and activation of fibrinolysis in selected series of arylaliphatic acids
1984, Vol. 49, Issue 1, pp. 122–136 [Abstract] - Miroslav Kuchař, Václav Rejholec, Bohumila Brunová, Jaroslava Grimová, Oluše Matoušová, Oldřich Němeček and Hana Čepeláková
Benzyloxyarylaliphatic acids: Synthesis and quantitative relations between structure and antiinflammatory activity
1982, Vol. 47, Issue 9, pp. 2514–2524 [Abstract] - Miroslav Kuchař, Bohumila Brunová, Václav Rejholec, Zdeněk Roubal and Oldřich Němeček
The synthesis of arylpropionic acids and the quantitative relationship between the structure and the activation of fibrinolysis
1981, Vol. 46, Issue 5, pp. 1173–1187 [Abstract] - Miroslav Kuchař, Bohumila Brunová, Zdeněk Roubal, Jiří Schlanger and Oldřich Němeček
Synthesis of arylacetic acids and their effect on activation of fibrinolysis. Quantitative relations between structure and biological activity
1980, Vol. 45, Issue 5, pp. 1401–1409 [Abstract] - Miroslav Kuchař, Václav Rejholec, Zdeněk Roubal and Oldřich Němeček
Quantitative relationships between structure and fibrinolytic activity in the series of α-methyl-β-arylpropionic acids
1979, Vol. 44, Issue 1, pp. 183–193 [Abstract]