Collect. Czech. Chem. Commun. 1984, 49, 2819-2827
https://doi.org/10.1135/cccc19842819

Synthesis, IR spectra, and antimicrobial activity of some bis-ammonium salts of N,N'-bis(2-dimethylaminoethyl)methylamine

Ferdinand Devínskýa, Ľubomíra Masárováa, Ivan Lackoa and Dušan Mlynarčíkb

a Department of Inorganic and Organic Chemistry
b Department of Biochemistry and Microbiology, Faculty of Pharmacy, Comenius University, 832 32 Bratislava

Abstract

Preparation of 2-bromoethyl alkanoates and alkenoates, N,N'-bis(2-dimethylaminoethyl)methylamine (pentamethyldiethylenetriamine) and some of its bis-ammonium salts is described. IR spectra of the esters and ammonium salts have been interpreted. Antimicrobial activity against Staphylococcus aureus, Escherichia coli and Candida albicans for the bis-ammonium salts has been determined.