Collect. Czech. Chem. Commun.
1984, 49, 1764-1773
https://doi.org/10.1135/cccc19841764
Nucleophilic substitution reaction of keto-allylic systems with a heterocyclic ring in γ-position
Vladimír Žvak, Jaroslav Kováč, Miloslava Dandárová, Tibor Gracza and Miroslav Kríž
Department of Organic Chemistry, Slovak Institute of Technology, 812 37 Bratislava
Abstract
Keto allylic systems with a heterocyclic ring in γ-position were prepared; these undergo nucleophilic substitution reactions with amines, where a replacement of bromine at the bromomethyl group takes place in contrast to benzene analogues, where the nucleophilic attacks the γ-carbon of the keto-allylic system.
