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Collect. Czech. Chem. Commun. 1985, 50, 228-244
https://doi.org/10.1135/cccc19850228

Conformation of branched polypeptides based on poly(L-lysine): The effect of terminal amino acids in the branches

Hana Votavováa, Ferenc Hudeczb, Judit Kajtárb, Jaroslav Šponara, Karel Bláhaa and Mária Szekerkeb

a Institute of Organic Chemistry and Biochemistry, Czechoslovak Academy of Sciences, 166 10 Prague 6, Czechoslovakia
b Research Group for Peptide Chemistry, Hungarian Academy of Sciences, Budapest, Hungary

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  • Nagy Ildik� B., Majer Zsuzsa, Hudecz Ferenc: Effect of phospholipid bilayers on solution conformation of branched polymeric polypeptides and peptide-polymer conjugates. Biopolymers 2001, 58, 152. <https://doi.org/10.1002/1097-0282(200102)58:2<152::AID-BIP40>3.0.CO;2-V>
  • Mezö G., Kajtár J., Nagy I., Szekerke M., Hudecz F.: Carrier design: Synthesis and conformational studies of poly (L-lysine) based branched polypeptides with hydroxyl groups in the side chains. Biopolymers (Biospectroscopy) 1997, 42, 719. <https://doi.org/10.1002/(SICI)1097-0282(199711)42:6<719::AID-BIP9>3.0.CO;2-X>
  • Mezö G., Kajtár J., Nagy I., Szekerke M., Hudecz F.: Carrier design: Synthesis and conformational studies of poly (L-lysine) based branched polypeptides with hydroxyl groups in the side chains. Biopolymers 1997, 42, 719. <https://doi.org/10.1002/(SICI)1097-0282(199711)42:6<719::AID-BIP9>3.0.CO;2-X>
  • Mezö G., Kajtár J., Hudecz F., Szekerke M.: Carrier design: Conformational studies of amino acid (X) and oligopeptide (X‐DL‐Alam) substituted poly(L‐lysine). Biopolymers 1993, 33, 873. <https://doi.org/10.1002/bip.360330603>
  • Hudecz F., Clegg J. A., Kajtar J., Embleton M. J., Pimm M. V., Szekerke M., Baldwin R. W.: Influence of carrier on biodistribution and in vitro cytotoxicity of methotrexate-branched polypeptide conjugates. Bioconjugate Chem. 1993, 4, 25. <https://doi.org/10.1021/bc00019a004>
  • Hudecz F., Gaál D., Kurucz I., Lányi Á., Kovács A.L., Mezö G., Rajnavölgyi É., Szekerke M.: Carrier design: cytotoxicity and immunogenicity of synthetic branched polypeptides with poly(L-lysine) backbone. J Controlled Release 1992, 19, 231. <https://doi.org/10.1016/0168-3659(92)90079-7>
  • Hudecz F., Price M.R.: Monoclonal antibody binding to peptide epitopes conjugated to synthetic branched chain polypeptide carriers. J  Immunol Methods 1992, 147, 201. <https://doi.org/10.1016/S0022-1759(12)80009-3>
  • Hudecz Ferenc, Clegg J. A., Kajtar J., Embleton M. J., Szekerke M., Baldwin R. W.: Synthesis, conformation, biodistribution and in vitro cytotoxicity of daunomycin-branched polypeptide conjugates. Bioconjugate Chem. 1992, 3, 49. <https://doi.org/10.1021/bc00013a008>
  • Clegg J. A., Hudecz F., Mezo G., Pimm M. V., Szekerke M., Baldwin R. W.: Carrier design: biodistribution of branched polypeptides with a poly(L-lysine) backbone. Bioconjugate Chem. 1990, 1, 425. <https://doi.org/10.1021/bc00006a009>
  • Mező G., Hudecz F., Kajtár J., Szókán Gy., Szekerke M.: The influence of the side‐chain sequence on the structure–activity correlations of immunomodulatory branched polypeptides. Synthesis and conformational analysis of new model polypeptides. Biopolymers 1989, 28, 1801. <https://doi.org/10.1002/bip.360281013>
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  • Hudecz Ferenc, Kajtár Judit, Szekerke Mária: Influence of side-chain-terminating moieties on the conformation of branched polypeptides and their conjugates with 4-ethoxymethylene-2-phenyl-5(4H)-oxazolone. biophys chem 1988, 31, 53. <https://doi.org/10.1016/0301-4622(88)80008-5>
  • Hudecz Ferenc, Mezö Gábor, Szekerke Mária, Gergely János, Rajnavölgyi Éva: Isotype distribution and fine specificity of the antibody response of inbred mouse strains to four compounds belonging to a new group of synthetic branched polypeptides. Molec Immunol 1986, 23, 27. <https://doi.org/10.1016/0161-5890(86)90168-9>