Collect. Czech. Chem. Commun. 1986, 51, 2617-2625
https://doi.org/10.1135/cccc19862617

On the quantitative relations between structure and antiaggregation activity of ω-aryl-ω-oxoalkanoic acids

Miroslav Kuchařa, Bohumila Brunováa, Jaroslava Grimováa, Václav Rejholeca and Václav Čepelákb

a Research Institute for Pharmacy and Biochemistry, 130 60 Prague 3
b Medical Faculty, Charles University, Plzen

Individual author index pages


Other CCCC articles of these authors

  • Václav Kozmík, Bedřich Košata, Jiří Svoboda* and Miroslav Kuchař
    A Study of 5-Nitroindole Alkylation
    2006, Vol. 71, Issue 5, pp. 679–690 [Abstract]
  • Miroslav Kuchař*, Bohumila Brunová, Richard Junek, Robert Rodling, Josef Hájíček, Vladimíra Panajotová and Antonín Jandera
    The Antileukotrienic Derivatives and Homologues of [(Quinolin-2-ylmethoxy)sulfanyl]benzoic Acids with Reduced Lipophilicity
    2005, Vol. 70, Issue 9, pp. 1357–1371 [Abstract]
  • Miroslav Kuchař*, Vojtěch Kmoníček, Vladimíra Panajotová, Antonín Jandera, Bohumila Brunová, Richard Junek, Věra Bucharová, Jan Čejka and Dalibor Šatinský
    Derivatives of (Phenylsulfanyl)benzoic Acids with Multiple Antileukotrienic Activity
    2004, Vol. 69, Issue 11, pp. 2098–2120 [Abstract]
  • Vladimír Wsól*, Barbora Szotáková, Vendula Baliharová, Luděk Šišpera, Michal Holčapek, Lenka Kolářová, Bohumila Suchanová, Miroslav Kuchař and Lenka Skálová
    The Phase I Biotransformation of the Potential Antileukotrienic Drug Quinlukast in Rat Microsomes and Hepatocytes
    2004, Vol. 69, Issue 3, pp. 689–702 [Abstract]
  • Jiří Svoboda*, Michal Štádler, Antonín Jandera, Vladimíra Panajotová and Miroslav Kuchař
    Synthesis and Biological Evaluation of New Antiinflammatory 1-Benzothiophene-2-carboxanilides
    2000, Vol. 65, Issue 7, pp. 1082–1092 [Abstract]
  • Miroslav Kuchař, Kateřina Čulíková, Vladimíra Panajotovová, Bohumila Brunová, Antonín Jandera and Vojtěch Kmoníček
    2,4-Dihydroxyacetophenone Derivatives as Antileukotrienics with a Multiple Activity Mechanism
    1998, Vol. 63, Issue 1, pp. 103–114 [Abstract]
  • Miroslav Kuchař, Marie Poppová, Antonín Jandera, Vladimíra Panajotovová, Hana Zůnová, Miloš Buděšínský, Hana Tomková, Alexandr Jegorov and Jan Taimr
    Chiral Forms of 4-(2',4'-Difluorobiphenyl-4-yl)-2-methyl-4-oxobutanoic Acid (Flobufen) and Its Metabolite.Synthesis and Basic Biological Properties
    1997, Vol. 62, Issue 3, pp. 498–509 [Abstract]
  • Miroslav Kuchař, Václav Vosátka, Marie Poppová, Eva Knězová, Vladimíra Panajotovová, Hana Tomková and Jan Taimr
    Some Analogs of 4-(2',4'-Difluorobiphenyl-4-yl)-2-methyl-4-oxobutanoic Acid: Synthesis and Antiinflammatory Activity
    1995, Vol. 60, Issue 6, pp. 1026–1033 [Abstract]
  • Miroslav Kuchař, Marie Poppová, Hana Zůnová, Eva Knězová, Václav Vosátka and Marek Příhoda
    4-(2',4'-Difluorobiphenyl-4-yl)-2-methyl-4-oxobutanoic Acid and Its Derivatives
    1994, Vol. 59, Issue 12, pp. 2705–2713 [Abstract]
  • Ludmila Fišnerová, Bohumila Brunová, Zuzana Kocfeldová, Jana Tíkalová, Eva Maturová and Jaroslava Grimová
    Synthesis and analgetic efficiency of some oxy and oxo derivatives of 4(3H)-quinazolinone
    1991, Vol. 56, Issue 11, pp. 2373–2381 [Abstract]
  • Bohdan Schneider, Karel Huml and Václav Rejholec
    Three-dimensional structures of substituted benzylphenyl ethers
    1991, Vol. 56, Issue 10, pp. 2188–2198 [Abstract]
  • Bohdan Schneider, Václav Rejholec and Miroslav Kuchař
    Three-dimensional structures of substituted diphenyl sulfides
    1990, Vol. 55, Issue 11, pp. 2590–2601 [Abstract]
  • Jiří Jílek, Karel Šindelář, Jaroslava Grimová, Eva Maturová, Jiří Holubek, Emil Svátek, Jiřina Metyšová, Jan Metyš, Marta Hrubantová and Miroslav Protiva
    Potential antidepressant and anti-inflammatory agents: 4-(2-Propylthio)acetophenone oximes and 4-(2-propylthio)phenylalkanoic acids
    1990, Vol. 55, Issue 5, pp. 1266–1277 [Abstract]
  • Miloš Beran, Antonín Černý, Miroslav Kuchař, Hana Adamírová, Jiří Holubek, Jan Taimr, Jaroslav Vachek, Maria Frühaufová, Karel Řežábek, Martin Valchář and Ivan Krejčí
    9,10-Dihydroergopeptines modified in position 6
    1990, Vol. 55, Issue 3, pp. 819–832 [Abstract]
  • Miroslav Kuchař, Jaroslava Grimová, Václav Rejholec, Hana Tomková, Magda Jelínková and Jiří Holubek
    Use of QSAR in design of antiinflammatory fluorinated arylalkanoic acids
    1990, Vol. 55, Issue 1, pp. 296–306 [Abstract]
  • Miroslav Kuchař, Eva Maturová, Bohumila Brunová, Jaroslava Grimová, Hana Tomková and Jiří Holubek
    Quantitative relations between structure and antiinflammatory activity of aryloxoalkanoic acids
    1988, Vol. 53, Issue 8, pp. 1862–1872 [Abstract]
  • Miroslav Kuchař, Bohumila Brunová, Jaroslava Grimová, Stanislav Vaněček and Jiří Holubek
    Synthesis of cyclohexylaliphatic acids and their pharmacological properties
    1986, Vol. 51, Issue 12, pp. 2896–2908 [Abstract]
  • Ľubomír Janda, Zdeno Votický, Jozefína Jakubcová, Jan Světlík, Jaroslava Grimová and Eva Maturová
    Semisynthetic cephalosporines. Synthesis of some substituted tetrazolyl acetic and propionic acids
    1984, Vol. 49, Issue 7, pp. 1699–1712 [Abstract]
  • Ľubomír Janda, Zdeno Votický, Jan Světlík, Jaroslava Grimová and Eva Maturová
    Semisynthetic cephalosporines. The synthesis of some substituted tetrazolylacetic acids
    1984, Vol. 49, Issue 6, pp. 1505–1514 [Abstract]
  • Miroslav Kuchař, Bohumila Brunová, Václav Rejholc, Magda Jelínková, Jiří Holubek and Oldřich Němeček
    Quantitative relations between structure and activation of fibrinolysis in selected series of arylaliphatic acids
    1984, Vol. 49, Issue 1, pp. 122–136 [Abstract]
  • Karel Šindelář, Jiří Holubek, Miroslav Ryska, Emil Svátek, Jiří Urban, Jaroslava Grimová, Irena Červená, Marta Hrubantová and Miroslav Protiva
    Dibenzo[b,f]thiepin-10-carbonitrile, its 10,11-dihydro derivative, some transformation products and related compounds
    1983, Vol. 48, Issue 4, pp. 1187–1211 [Abstract]
  • Miroslav Kuchař, Václav Rejholec, Zdeněk Roubal and Oluše Matoušová
    The effects of lipophilicity on the inhibition of denaturation of serum albumin and on the activation of fibrinolysis observed with a series of benzyloxyarylaliphatic acids
    1983, Vol. 48, Issue 4, pp. 1077–1088 [Abstract]
  • Miroslav Kuchař, Václav Rejholec, Bohumila Brunová, Jaroslava Grimová, Oluše Matoušová, Oldřich Němeček and Hana Čepeláková
    Benzyloxyarylaliphatic acids: Synthesis and quantitative relations between structure and antiinflammatory activity
    1982, Vol. 47, Issue 9, pp. 2514–2524 [Abstract]
  • Miroslav Protiva, Zdeňka Kopicová and Jaroslava Grimová
    Synthesis of several 1-(aminoacyl)-4-cinnamylpiperazines as potential analgetics
    1982, Vol. 47, Issue 2, pp. 636–643 [Abstract]
  • Miroslav Kuchař, Bohumila Brunová, Václav Rejholec, Zdeněk Roubal and Oldřich Němeček
    The synthesis of arylpropionic acids and the quantitative relationship between the structure and the activation of fibrinolysis
    1981, Vol. 46, Issue 5, pp. 1173–1187 [Abstract]
  • Miroslav Kuchař, Bohumila Brunová, Zdeněk Roubal, Jiří Schlanger and Oldřich Němeček
    Synthesis of arylacetic acids and their effect on activation of fibrinolysis. Quantitative relations between structure and biological activity
    1980, Vol. 45, Issue 5, pp. 1401–1409 [Abstract]
  • Miroslav Kuchař, Václav Rejholec, Zdeněk Roubal and Oldřich Němeček
    Quantitative relationships between structure and fibrinolytic activity in the series of α-methyl-β-arylpropionic acids
    1979, Vol. 44, Issue 1, pp. 183–193 [Abstract]