Collect. Czech. Chem. Commun. 1988, 53, 2637-2644
https://doi.org/10.1135/cccc19882637

Synthesis of modified human C-peptide and its fragments

Běla Bendlováa, Michal Leblb, Pavel Štolbaa and Luboslav Stárkaa

a Research Institute of Endocrinology, 116 94 Prague 1
b Institute of Organic Chemistry and Biochemistry, Czechoslovak Academy of Sciences, 166 10 Prague 6

Individual author index pages


Other CCCC articles of these authors

  • Michal Lebl, David L. Heiner, Aaron C. Jones, Steven P. Fambro, Mark J. Nibbe, Steven R. Burgett and Brett M. Ellman
    Automatic oligonucleotide synthesizer utilizing the concept of parallel processing
    Symposium Series 2011, Vol. 12, pp. 264–267 [Abstract]
    Published online 2015-08-20 10:10:52
  • Martin Hill*, Helena Havlíková, Jan Klak, Marie Bičíková, Vladimír Pouzar, Richard Hampl and Luboslav Stárka
    Rapid Immunoassay for Pregnenolone Sulfate and Its Applications in Endocrinology
    2002, Vol. 67, Issue 1, pp. 140–162 [Abstract]
  • Richard Hampl*, Martin Hill and Luboslav Stárka
    Detection and Quantification of 7-Hydroxydehydroepiandrosterone Epimers in Three Body Fluids
    2002, Vol. 67, Issue 1, pp. 10–18 [Abstract]
  • Michal Lebl*, Christine Burger, Brett Ellman, David Heiner, Georges Ibrahim, Aaron Jones, Mark Nibbe, Jaylynn Thompson, Petr Mudra, Vít Pokorný, Pavel Poncar and Karel Ženíšek
    Fully Automated Parallel Oligonucleotide Synthesizer
    2001, Vol. 66, Issue 8, pp. 1299–1314 [Abstract]
  • Luboslav Stárka, Martin Hill, Richard Hampl, Marie-Irène Malewiak, Aïda Benalycherif, Robert Morfin, Jaroslav Kolena and Sona Scsuková
    Studies on the Mechanism of Antiglucocorticoid Action of 7α-Hydroxydehydroepiandrosterone
    1998, Vol. 63, Issue 10, pp. 1683–1698 [Abstract]
  • Josef Vágner, Viktor Krchňák, Michal Lebl and George Barany
    Solid-Phase Organic Synthesis: Creation of Carbon-Carbon Double Bonds Under Mild Conditions by Wittig-Type Reactions
    1996, Vol. 61, Issue 12, pp. 1697–1702 [Abstract]
  • Oldřich Lapčík, Richard Hampl, Martin Hill, Luboslav Stárka, Alexander Kasal, Vladimír Pouzar and Zdeněk Putz
    Radioimmunological and Chromatographic Properties of Tyrosine Methyl Ester Conjugates with Stereoisomeric Steroid Carboxy Derivatives
    1996, Vol. 61, Issue 5, pp. 799–807 [Abstract]
  • Markéta Rinnová and Michal Lebl
    Molecular Diversity and Libraries of Structures: Synthesis and Screening
    1996, Vol. 61, Issue 2, pp. 171–231 [Abstract]
  • Alexander Kasal, Ladislav Kohout and Michal Lebl
    Synthesis of a Scaffold for the Creation of Non-Peptide Libraries
    1995, Vol. 60, Issue 12, pp. 2147–2155 [Abstract]
  • Zdenko Procházka, Jiřina Slaninová, Per Melin, Carl-Johan Aurell and Michal Lebl
    The Deamino-Carba Analogs of Vasotocin. Synthesis and Some Biological Properties
    1994, Vol. 59, Issue 2, pp. 421–428 [Abstract]
  • Miroslava Žertová, Zdenko Procházka, Jiřina Slaninová, Tomislav Barth, Pavel Majer and Michal Lebl
    The Analogs of [D-Har8]Vasopressin with Di- and Trisubstituted Phenylalanine in Position 2; Synthesis and Some Biological Properties
    1993, Vol. 58, Issue 11, pp. 2751–2760 [Abstract]
  • Alexander Kasal, Richard Hampl, Zdeněk Putz, Ladislav Kohout and Luboslav Stárka
    Preparation and Properties of Three Immunogens with a Spacer on the β-Side of the Steroid Skeleton and the Effect of Immunogen Structure on Specificity of the Obtained Antisera
    1992, Vol. 57, Issue 10, pp. 2166–2173 [Abstract]
  • B. C. Pal, Jiřina Slaninová, Tomislav Barth, Jerzy Trojnar and Michal Lebl
    Synthesis and Properties of "Hormonogene" and "Inhibitorogene" Type Oxytocin Analogs
    1992, Vol. 57, Issue 6, pp. 1345–1351 [Abstract]
  • Zdenko Procházka, Jiřina Slaninová, Tomislav Barth, Alena Stierandová, Jerzy Trojnar, Per Melin and Michal Lebl
    Analogs of Deamino Carba Oxytocin with Inhibitory Properties; Synthesis and Biological Activities
    1992, Vol. 57, Issue 6, pp. 1335–1344 [Abstract]
  • Miroslava Žertová, Zdenko Procházka, Jiřina Slaninová, Tomislav Barth, Pavel Majer and Michal Lebl
    The Analogs of 8-D-Homoarginin-vasopressin with O-Substituted Phenylalanine in Position 2: Synthesis and Some Biological Properties
    1992, Vol. 57, Issue 5, pp. 1103–1110 [Abstract]
  • Rudolf Ježek, Jan Franc, Jiřina Slaninová and Michal Lebl
    Sequence Modification in Neurohypophyseal Hormones
    1992, Vol. 57, Issue 3, pp. 621–624 [Abstract]
  • Ivo Frič, Michal Lebl and Victor J. Hruby
    Melanin Concentrating Hormone Analogs: Contraction of the Cyclic Structure. III. CD Spectroscopic Study
    1992, Vol. 57, Issue 3, pp. 614–620 [Abstract]
  • Miroslava Žertová, Zdenko Procházka, Jiřina Slaninová, Jana Škopková, Tomislav Barth and Michal Lebl
    Amino and Deamino Analogs of 8-D-Homoarginin-vasopressin with Modified Tyrosine in Position 2: Synthesis and Some Biological Properties
    1992, Vol. 57, Issue 3, pp. 604–613 [Abstract]
  • Marcel Pátek and Michal Lebl
    "Safety-Catch" Protecting Groups in Peptide Synthesis
    1992, Vol. 57, Issue 3, pp. 508–524 [Abstract]
  • Miroslava Žertová, Zdenko Procházka, Tomislav Barth, Jiřina Slaninová, Jana Škopková, Ivo Bláha and Michal Lebl
    Strong uterotonic inhibitors – analogs of 1-deamino-8-D-homoarginine-vasopressin with p-substituted phenylalanine in position 2
    1991, Vol. 56, Issue 8, pp. 1761–1767 [Abstract]
  • Miroslava Žertová, Zdenko Procházka, Ivo Bláha, Tomislav Barth, Jiřina Slaninová, Lenka Maletínská and Michal Lebl
    The analogs of 8-D-homoarginine-vasopressin with p-substituted phenylalanine in position 2; Synthesis and some biological properties
    1990, Vol. 55, Issue 12, pp. 3000–3007 [Abstract]
  • Zdenko Procházka, Juris E. Ancans, Jiřina Slaninová, Alena Machová, Tomislav Barth and Michal Lebl
    Synthesis and biological properties of vasopressin analogues containing 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
    1990, Vol. 55, Issue 4, pp. 1099–1105 [Abstract]
  • Giorgio Fassina, Michal Lebl and Irwin M. Chaiken
    Screening the recognition properties of peptide hormone sequence mutants by analytical high performance liquid affinity chromatography on immobilized neurophysin
    1988, Vol. 53, Issue 11, pp. 2627–2636 [Abstract]
  • Zdenko Procházka, Juris E. Ancans, Jiřina Slaninová, Alena Machová, Tomislav Barth, Jana Škopková, Miloš Buděšínský, Františka Pavlíková and Michal Lebl
    Synthesis and properties of analogues of vasopressin with 1-aminocyclopropane-1-carboxylic acid in position 9
    1988, Vol. 53, Issue 11, pp. 2604–2616 [Abstract]
  • Viktor Krchňák, Josef Vágner, Pavel Šafář and Michal Lebl
    Noninvasive continuous monitoring of solid-phase peptide synthesis by acid-base indicator
    1988, Vol. 53, Issue 11, pp. 2542–2548 [Abstract]
  • Pavel Mader, Věra Veselá, Michael Heyrovský, Michal Lebl and Milena Braunsteinová
    Polarography of the oxytocin and vasopressin synthetic analogs
    1988, Vol. 53, Issue 7, pp. 1579–1605 [Abstract]
  • Michal Lebl, Victor J. Hruby, Jiřina Slaninová and Tomislav Barth
    Solid phase synthesis and biological activities of oxytocin carba analogues containing threonine in position 4
    1985, Vol. 50, Issue 2, pp. 418–427 [Abstract]
  • Michal Lebl, Tomislav Barth, Linda Servítová, Jiřina Slaninová and Karel Jošt
    Oxytocin analogues with inhibitory properties, containing in position 2 a hydrophobic amino acid of D-configuration
    1985, Vol. 50, Issue 1, pp. 132–145 [Abstract]
  • Luboslav Stárka, Alexander Kasal, Marie Bičíková and Richard Hampl
    Preparation and synandrogenic activity of 17β-hydroxy-4,5-seco-5-androsten-3-one
    1984, Vol. 49, Issue 12, pp. 2942–2947 [Abstract]
  • Michal Lebl, Wayne L. Cody, Brian C. Wilkes, Victor J. Hruby, Anna M. de L. Castrucci and Mac E. Hadley
    Modification of the disulfide bridge in cyclic melanotropins
    1984, Vol. 49, Issue 11, pp. 2680–2688 [Abstract]
  • Michal Lebl, Tomislav Barth, Linda Servítová, Jiřina Slaninová and Pavel Hrbas
    Synthesis and properties of carba-6-analogues of oxytocin containing a deaminopenicillamine residue in position 1
    1984, Vol. 49, Issue 9, pp. 2012–2023 [Abstract]
  • Michal Lebl, Tomislav Barth, Denis J. Crankshaw, Bohuslav Černý, Edwin E. Daniel, A. K. Grover and Karel Jošt
    Synthesis and properties of [2-[3,5-3H2]-tyrosine,4-glutamic acid]deamino-1-carba-oxytocin
    1984, Vol. 49, Issue 8, pp. 1921–1926 [Abstract]
  • Zdenko Procházka, Michal Lebl, Tomislav Barth, Jan Hlaváček, Antonín Trka, Miloš Buděšínský and Karel Jošt
    Synthesis and properties of oxytocin analogues modified in the tripeptide side chain
    1984, Vol. 49, Issue 3, pp. 642–652 [Abstract]
  • Daniel Butlen, Tomislav Barth, Bernard Cantau, Gilles Guillon, Serge Jard, Michal Lebl, František Brtník and Karel Jošt
    The structural requirements of oxytocin and vassopressin analogues for the activation of adenylate cyclase in the rat kidney medullary membrane system
    1983, Vol. 48, Issue 11, pp. 3166–3176 [Abstract]
  • Tomislav Barth, Bernard Cantau, Daniel Butlen, Gilles Guillon, Serge Jard, Michal Lebl and Karel Jošt
    Oxytocin and vasopressin analogues capable of competition with vasopressin binding to rat liver membranes
    1983, Vol. 48, Issue 6, pp. 1788–1795 [Abstract]
  • Michal Lebl, Pavel Hrbas, Jana Škopková, Jiřina Slaninová, Alena Machová, Tomislav Barth and Karel Jošt
    Synthesis and properties of oxytocin analogues with high and selective natriuretic activity
    1982, Vol. 47, Issue 9, pp. 2540–2560 [Abstract]
  • Michal Lebl, Jan Pospíšek, Jan Hlaváček, Tomislav Barth, Petr Maloň, Linda Servítová, Karel Hauzer and Karel Jošt
    Analogues of neurohypophysial hormones, containing tert-leucine: Synthesis and properties
    1982, Vol. 47, Issue 2, pp. 689–701 [Abstract]
  • Tomislav Barth, Jiřina Slaninová, Linda Servítová, Michal Lebl, Christine Kotsira-Engonopoulos, Chrysa Tzougraki, Iphigenia Photaki, Milan Krojidlo and Karel Jošt
    The effect of some structural modifications of the oxytocin molecule on the duration of the galactogogic response
    1981, Vol. 46, Issue 10, pp. 2441–2445 [Abstract]
  • Jiřina Slaninová, Michal Lebl, Tomislav Barth and Karel Jošt
    The effect of magnesium ions on the uterotonic activity of carba analogues of oxytocin modified in position 4
    1981, Vol. 46, Issue 7, pp. 1689–1692 [Abstract]
  • Zdenko Procházka, Michal Lebl, Linda Servítová, Tomislav Barth and Karel Jošt
    Synthesis and pharmacological properties of [2-p-fluorophenylalanine]deamino-1-carba-oxytocin and its diastereoisomeric sulfoxides
    1981, Vol. 46, Issue 4, pp. 947–956 [Abstract]
  • Tomislav Barth, Jiřina Slaninová, Michal Lebl and Karel Jošt
    Biological activities and protracted action of carba-analogues of deamino-oxytocin with O-methyltyrosine in position 2
    1980, Vol. 45, Issue 11, pp. 3045–3050 [Abstract]
  • Michal Lebl
    High-performance liquid chromatography of carba-analogues of oxytocin; a method for the determination of sulfides and sulfoxides in peptides
    1980, Vol. 45, Issue 11, pp. 2927–2937 [Abstract]
  • Michal Lebl, Tomislav Barth, Jana Škopková and Karel Jošt
    Synthesis and some pharmacological properties of [7-glycine, 8-ornithine]vasopressin and two of its analogues
    1980, Vol. 45, Issue 10, pp. 2865–2871 [Abstract]
  • Michal Lebl, Tomislav Barth and Karel Jošt
    Synthesis and pharmacological properties of oxytocin analogues modified simultaneously in position 2 and in the disulfide bridge
    1980, Vol. 45, Issue 10, pp. 2855–2864 [Abstract]
  • Michal Lebl, Alena Machová, Pavel Hrbas, Tomislav Barth and Karel Jošt
    Analogues of deamino-1-carba-oxytocin with an aliphatic amino acid in position 4: chemical synthesis and biological activities
    1980, Vol. 45, Issue 10, pp. 2714–2723 [Abstract]
  • Michal Lebl, Vera Bojanovska, Tomislav Barth and Karel Jošt
    Synthesis and properties of oxytocin analogues acting as irreversible inhibitors of the uterotonic response to oxytocin
    1979, Vol. 44, Issue 8, pp. 2573–2582 [Abstract]
  • Michal Lebl, Tomislav Barth and Karel Jošt
    Analogues of oxytocin with esters of glutamic acid instead of glutamine in position 4: Synthesis of a compound with high and specific galactogogic activity
    1979, Vol. 44, Issue 8, pp. 2563–2572 [Abstract]
  • Michal Lebl, Anastasia Dimeli, Vera Bojanovska, Jiřina Slaninová, Tomislav Barth and Karel Jošt
    Synthesis and some biological properties of amides derived from [4-glutamic acid]deamino-1-carba-oxytocin
    1979, Vol. 44, Issue 8, pp. 2556–2562 [Abstract]
  • Michal Lebl, Tomislav Barth and Karel Jošt
    Synthesis, reduction, and pharmacological properties of the sulfoxides of some carba-analogues of oxytocin
    1978, Vol. 43, Issue 6, pp. 1538–1556 [Abstract]
  • Michal Lebl, Tomislav Barth and Karel Jošt
    Nα-Glycyl-glycyl-glycyl-8-ornithine-vasopressin: A trypsin resistant vasopressin analog with a specific pressor effect
    1978, Vol. 43, Issue 5, pp. 1300–1305 [Abstract]
  • Michal Lebl and Karel Jošt
    Synthesis of [4-glutamic acid]deamino-1-carba-oxytocin
    1978, Vol. 43, Issue 2, pp. 523–534 [Abstract]