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Collect. Czech. Chem. Commun. 1988, 53, 1078-1085
https://doi.org/10.1135/cccc19881078

In vitro release of chloramphenicol from poly[N-(2-hydroxypropyl)methacrylamide] carriers by Cathepsin B

Karel Ulbricha, Olga Nazarovaa, Eugenii Panarina, Miroslav Baudyšb and Michail V. Solovskiic

a Institute of Macromolecular Chemistry, Czechoslovak Academy of Sciences, 162 06 Prague 6, Czechoslovakia
b Institute of Organic Chemistry and Biochemistry, Czechoslovak Academy of Sciences, 166 10 Prague 6, Czechoslovakia
c Institute of Macromolecular Compounds, Academy of Sciences of the U.S.S.R., 199 004 Leningrad, U.S.S.R.

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  • Solovskij M. V., Nikolskaya N. V., Tarabukina E. B., Denisov V.M., Adamov A. V., Klenin S. I.: Synthesis and properties of branched chemodegradable polymers based on N-vinylpyrrollidone and N-(2-hydroxypropyl)methacrylamide, carriers of biologically active compounds. Designed Monomers and Polymers 2004, 7, 63. <https://doi.org/10.1163/156855504322890043>
  • El-Shorbagi Abdel-Nasser: New Tetrahydro-2H-1,3,5-thiadiazine-2-thione Derivatives as Potential Antimicrobial Agents. Arch Pharm Pharm Med Chem 2000, 333, 281. <https://doi.org/10.1002/1521-4184(20009)333:9<281::AID-ARDP281>3.0.CO;2-E>
  • El-Shorbagi Abdel-Nasser: New Tetrahydro-2H-1,3,5-thiadiazine-2-thione Derivatives as Potential Antimicrobial Agents. Arch. Pharm. Pharm. Med. Chem. 2000, 333, 281. <https://doi.org/10.1002/1521-4184(20009)333:9<281::AID-ARDP281>3.0.CO;2-E>
  • Nazarova O. V., Ulbrich K., Panarin E. F., Chetverikova T. D., Afinogenov G. E., Strohalm J.: Synthesis and antimicrobial activity of chloramphenicol derivatives based on N-[2-hydroxypropyl]methacrylamide copolymers having oligopeptides spacers. Pharm Chem J 1993, 27, 101. <https://doi.org/10.1007/BF00781069>
  • Říhová B., Větvička V., Strohalm J., Ulbrich K., Kopeček J.: Action of polymeric prodrugs based on N-(2-hydroxypropyl)meth- acrylamide copolymers. I. Suppression of the antibody response and proliferation of mouse splenocytes in vitro. J Controlled Release 1989, 9, 21. <https://doi.org/10.1016/0168-3659(89)90030-8>