Collect. Czech. Chem. Commun.
1988, 53, 1543-1548
https://doi.org/10.1135/cccc19881543
Synthesis of 2-methyl-3-(5-phenyl or 1,5-diphenyl-2-pyrazolin-3-yl)-1,8-naphthyridines
Maringanti Thirumala Chary, Kaleru Mogilaiah and Bathula Sreenivasulu
Department of Chemistry, Kakatyia University, Warangal 506 009, India
Abstract
3-Cinnamoyl-2-methyl-1,8-naphthyridines II have been synthesized utilizing Claisen-Schmidt condensation of 3-acetyl-2-methyl-1,8-naphthyridine I with aromatic aldehydes. The cinnamoyl naphthyridines react with hydrazine hydrate and phenylhydrazine to create the corresponding pyrazolinyl 1,8-naphthyridine derivatives (III and IV). The structures II-IV have been confirmed by their elemental analyses and spectral data. Some of the compounds have been screened for their fungicidal activity.
