Collect. Czech. Chem. Commun.
1989, 54, 206-214
https://doi.org/10.1135/cccc19890206
2-Amino-substituted derivatives of benzimidazoles from 2-isothiocyanato carboxylates
Ľubomír Flocha, Michal Uhera and Ján Leškob
a Department of Organic Chemistry, Slovak Technical University, 812 37 Bratislava
b Laboratory of Mass Spectrometry, Slovak Technical University, 812 37 Bratislava
Abstract
2-Isothiocyanato carboxylates react with o-phenylenediamine to give N,N'-substituted thioureas, which cyclize to yield 2-amino-substituted derivatives of imidazole. The structure of these compounds was corroborated by IR, UV, 1H, 13C NMR, and mass spectral methods.
