Collect. Czech. Chem. Commun. 1990, 55, 819-832
https://doi.org/10.1135/cccc19900819

9,10-Dihydroergopeptines modified in position 6

Miloš Beran, Antonín Černý, Miroslav Kuchař, Hana Adamírová, Jiří Holubek, Jan Taimr, Jaroslav Vachek, Maria Frühaufová, Karel Řežábek, Martin Valchář and Ivan Krejčí

Research Institute for Pharmacy and Biochemistry, 130 60 Prague 3

Individual author index pages


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  • Evžen Kasafírek, Jaroslav Moural, Jarmila Vinšová, Antonín Šturc and Jan Taimr
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  • Alexandra Šilhánková, Karel Šindelář, Karel Dobrovský, Ivan Krejčí, Jarmila Hodková and Zdeněk Polívka
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  • Miroslav Kuchař, Václav Vosátka, Marie Poppová, Eva Knězová, Vladimíra Panajotovová, Hana Tomková and Jan Taimr
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  • Karel Šindelář, Karel Dobrovský, Ivan Krejčí and Zdeněk Polívka
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  • Miroslav Kuchař, Marie Poppová, Hana Zůnová, Eva Knězová, Václav Vosátka and Marek Příhoda
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    1994, Vol. 59, Issue 10, pp. 2343–2350 [Abstract]
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    1994, Vol. 59, Issue 5, pp. 1126–1136 [Abstract]
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  • Alexandra Šilhánková, Karel Dobrovský, Ivan Krejčí and Zdeněk Polívka
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  • Vladimír Valenta, Marie Vlková, Martin Valchář, Karel Dobrovský and Zdeněk Polívka
    Potential antidepressants: 3-Aryl-3-(arylthio)propylamines as selective inhibitors of 5-hydroxytryptamine re-uptake in the brain
    1991, Vol. 56, Issue 7, pp. 1525–1533 [Abstract]
  • Karel Šindelář, Josef Pomykáček, Jiří Holubek, Emil Svátek, Martin Valchář, Karel Dobrovský, Jiřina Metyšová and Zdeněk Polívka
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    1991, Vol. 56, Issue 2, pp. 459–477 [Abstract]
  • Karel Šindelář, Josef Pomykáček, Martin Valchář, Karel Dobrovský, Jiřina Metyšová and Zdeněk Polívka
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    1991, Vol. 56, Issue 2, pp. 449–458 [Abstract]
  • Vladimír Valenta, Jiří Holubek, Emil Svátek, Martin Valchář, Ivan Krejčí and Miroslav Protiva
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    1990, Vol. 55, Issue 11, pp. 2756–2764 [Abstract]
  • Bohdan Schneider, Václav Rejholec and Miroslav Kuchař
    Three-dimensional structures of substituted diphenyl sulfides
    1990, Vol. 55, Issue 11, pp. 2590–2601 [Abstract]
  • Vladimír Valenta, Jiří Holubek, Emil Svátek and Miroslav Protiva
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    1990, Vol. 55, Issue 9, pp. 2304–2316 [Abstract]
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    Tricyclic neuroleptics: Synthesis of metabolites of isofloxythepin and some related compounds
    1990, Vol. 55, Issue 9, pp. 2282–2303 [Abstract]
  • Jiří Jílek, Miroslav Rajšner, Vladimír Valenta, Miloš Borovička, Jiří Holubek, Miroslav Ryska, Emil Svátek, Jan Metyš and Miroslav Protiva
    Synthesis of piperidine derivatives as potential analgetic agents
    1990, Vol. 55, Issue 7, pp. 1828–1853 [Abstract]
  • Vojtěch Kmoníček, Emil Svátek, Jiří Holubek, Miroslav Ryska, Martin Valchář and Miroslav Protiva
    Synthesis of 1-acyl- and 1-(thioacyl)-4-benzylpiperazines as potential antidepressants
    1990, Vol. 55, Issue 7, pp. 1817–1827 [Abstract]
  • Vladimír Valenta, Karel Šindelář, Jiří Holubek, Miroslav Ryska, Ivan Krejčí, Antonín Dlabač and Miroslav Protiva
    Potential nootropic agents: Synthesis of a series of (2-oxo-1-pyrrolidinyl)acetic acid piperazides
    1990, Vol. 55, Issue 6, pp. 1613–1629 [Abstract]
  • Karel Šindelář, Jiří Holubek, Ivan Koruna, Marta Hrubantová and Miroslav Protiva
    Modified syntheses of 2-(methylthio)-10-(2-(1-methyl-2-piperidinyl)ethyl)phenothiazine (thioridazine) and 1-(3-(2-(methylsulfonyl)-10-phenothiazinyl)propyl)-piperidine-4-carboxamide (metopimazine)
    1990, Vol. 55, Issue 6, pp. 1586–1601 [Abstract]
  • Vladimír Valenta, Jiří Holubek, Emil Svátek, Oluše Matoušová, Jiřina Metyšová and Miroslav Protiva
    Potential neuroleptics of the orthopramide series; synthesis of heterocyclic 5-amino-2-methoxybenzamides and of some related compounds
    1990, Vol. 55, Issue 5, pp. 1297–1310 [Abstract]
  • Miroslav Protiva, Vladimír Valenta, Zdeňka Kopicová, Juraj Lukáč, Jiří Holubek and Ivan Krejčí
    Potential cerebral stimulants: Esters of 2-dimethylaminoethanol with some lipophilic carboxylic acids
    1990, Vol. 55, Issue 5, pp. 1278–1289 [Abstract]
  • Jiří Jílek, Karel Šindelář, Jaroslava Grimová, Eva Maturová, Jiří Holubek, Emil Svátek, Jiřina Metyšová, Jan Metyš, Marta Hrubantová and Miroslav Protiva
    Potential antidepressant and anti-inflammatory agents: 4-(2-Propylthio)acetophenone oximes and 4-(2-propylthio)phenylalkanoic acids
    1990, Vol. 55, Issue 5, pp. 1266–1277 [Abstract]
  • Jiří Urban, Zdeněk Šedivý, Jiří Holubek, Emil Svátek, Miroslav Ryska, Ivan Koruna, Antonín Dlabač, Martin Valchář, Jiřina Metyšová, Zdeněk Polívka, Karel Šindelář, Josef Pomykáček, Marta Hrubantová and Miroslav Protiva
    Potential antidepressants: 1-(2-(Methoxy- and hydroxyphenylthio)phenyl)-2-propylamines
    1990, Vol. 55, Issue 4, pp. 1077–1098 [Abstract]
  • Vladimír Valenta, Marie Vlková, Jiří Holubek, Emil Svátek, Jiřina Metyšová and Miroslav Protiva
    Potential neuroleptics of the orthopramide series; Synthesis of N-(3-(tert.amino)propyl)-5-sulfamoyl-2-methoxybenzamides
    1990, Vol. 55, Issue 3, pp. 797–808 [Abstract]
  • Karel Šindelář, Jiří Holubek, Emil Svátek, Jiří Schlanger, Antonín Dlabač, Martin Valchář, Marta Hrubantová and Miroslav Protiva
    Open-ring models of hetero-cannabinoids: Synthesis of 2-(alkylthio)-5-(2-aminoethyl)hydroquinone derivatives
    1990, Vol. 55, Issue 3, pp. 782–796 [Abstract]
  • Miroslav Kuchař, Jaroslava Grimová, Václav Rejholec, Hana Tomková, Magda Jelínková and Jiří Holubek
    Use of QSAR in design of antiinflammatory fluorinated arylalkanoic acids
    1990, Vol. 55, Issue 1, pp. 296–306 [Abstract]
  • Karel Šindelář, Vladimír Valenta, Jiří Holubek, Oluše Matoušová and Miroslav Protiva
    Potential antidepressants. Synthesis of 6,11-dihydrodibenzo[b,e]thiepin-11-yl (dimethylaminomethyl)phenyl ethers, sulfides, amines and some related compounds
    1990, Vol. 55, Issue 1, pp. 282–295 [Abstract]
  • Jiří Jílek, Karel Šindelář, Josef Pomykáček, Vojtěch Kmoníček, Zdeněk Šedivý, Marta Hrubantová, Jiří Holubek, Emil Svátek, Miroslav Ryska, Ivan Koruna, Martin Valchář, Antonín Dlabač, Jiřina Metyšová, Nataša Dlohožková and Miroslav Protiva
    Potential antidepressants: 2-(Methoxy- and hydroxyphenylthio)benzylamines as selective inhibitors of 5-hydroxytryptamine re-uptake in the brain
    1989, Vol. 54, Issue 12, pp. 3294–3338 [Abstract]
  • Zdeněk Polívka, Miloš Buděšínský, Jiří Holubek, Bohdan Schneider, Zdeněk Šedivý, Emil Svátek, Oluše Matoušová, Jan Metyš, Martin Valchář, Radomír Souček and Miroslav Protiva
    4H-Benzo[4,5]cyclohepta[1,2-b]thiophenes and 9,10-dihydro derivatives - Sulfonium analogues of pizotifen and ketotifen; Chirality of ketotifen; Synthesis of the 2-bromo derivative of ketotifen
    1989, Vol. 54, Issue 9, pp. 2443–2469 [Abstract]
  • Jiří Jílek, Jiří Urban, Vojtěch Kmoníček, Josef Pomykáček, Jiří Holubek, Emil Svátek, Oluše Matoušová, Jan Metyš, Martin Valchář, Stanislav Wildt and Miroslav Protiva
    Potential anticonvulsants: 3-Chlorobenzophenone derivatives
    1989, Vol. 54, Issue 8, pp. 2248–2260 [Abstract]
  • Karel Šindelář, Marta Hrubantová, Emil Svátek, Oluše Matoušová, Jiřina Metyšová, Martin Valchář and Miroslav Protiva
    Potential antidepressants: 4-(Thioaryloxy)piperidines
    1989, Vol. 54, Issue 8, pp. 2240–2247 [Abstract]
  • Jiří Jílek, Jiří Urban, Petr Taufmann, Jiří Holubek, Antonín Dlabač, Martin Valchář and Miroslav Protiva
    Potential antidepressants: 2-(Phenylthio)aralkylamines
    1989, Vol. 54, Issue 7, pp. 1995–2008 [Abstract]
  • Vladimír Valenta, Marie Vlková, Jiří Holubek, Jiřina Metyšová and Miroslav Protiva
    Potential antidepressants: 10-Amino-2-chloro-10,11-dihydrodibenzo[b,f]thiepins
    1989, Vol. 54, Issue 7, pp. 1979–1994 [Abstract]
  • Irena Červená, Jiří Holubek, Emil Svátek, Jan Metyš and Miroslav Protiva
    Potential antidepressants: 2-(Aminoalkoxy)biphenyls and some related ω-substituted 2-alkoxybiphenyls
    1989, Vol. 54, Issue 7, pp. 1966–1978 [Abstract]
  • Irena Červená, Jiří Holubek, Emil Svátek, Miroslav Ryska and Miroslav Protiva
    Potential antidepressants: 6-(Aminoalkoxy)dibenzo[b,f]thiepin-10(11H)-ones and 6-(aminoalkoxy)-10,11-dihydrodibenzo[b,f]thiepin-10-ols
    1989, Vol. 54, Issue 7, pp. 1955–1965 [Abstract]
  • Martin Mandel, Ludvík Novák, Miroslav Rajšner, Jiří Holubek and Vladislava Holá
    New synthesis of oxime-type beta-lactam antibiotics
    1989, Vol. 54, Issue 6, pp. 1734–1745 [Abstract]
  • Vojtěch Kmoníček, Zdeněk Vejdělek, Jiří Holubek, Martin Valchář and Miroslav Protiva
    Potential antidepressants: 1-(4-Aminoalkoxy)phenyl)-2-propylamines
    1989, Vol. 54, Issue 6, pp. 1721–1733 [Abstract]
  • Hana Hulinská, Miroslav Ryska, Ivan Koruna, Jiří Holubek, Jan Taimr, Emil Svátek and Miroslav Protiva
    Some further 2-(4-substituted 1-piperazinyl)acetamides derived from 6,11-dihydrodibenzo[b,e]thiepin. Transformations of 6,11-dihydrodibenzo[b,e]thiepin derivatives into anthraquinones, anthrones and anthracenes
    1989, Vol. 54, Issue 5, pp. 1388–1402 [Abstract]
  • Hana Hulinská, Miloš Buděšínský, Jiří Holubek, Oluše Matoušová, Hana Frycová and Miroslav Protiva
    Reactions of N-substituted 2-aminopyridines with chloroacetyl chloride; Formation of a new series of heterocyclic betaines: 1-Substituted 4-chloromethyl-2-oxopyrido[1,2-a]pyrimidin-5-ium-3-olates
    1989, Vol. 54, Issue 5, pp. 1376–1387 [Abstract]
  • Zdeněk Polívka, Vladimír Valenta, Karel Šindelář, Jiří Holubek, Miloš Buděšínský, Miroslav Ryska, Ivan Koruna, Jitka Kohoutová, Jan Metyš, Jiřina Metyšová, Martin Valchář and Miroslav Protiva
    Potential antidepressants: Saturated side chain amines derived from 6,11-dihydrodibenzo[b,e]thiepin and 4,9-dihydrothieno[2,3-c]-2-benzothiepin
    1989, Vol. 54, Issue 1, pp. 235–247 [Abstract]
  • Irena Červená, Jiří Holubek, Emil Svátek, Jan Metyš, Martin Valchář and Miroslav Protiva
    Potential antidepressants: Synthesis of two 4-(aminoalkoxy)dibenzo[b,e]thiepin-11(6H)-ones
    1989, Vol. 54, Issue 1, pp. 225–228 [Abstract]
  • Jiří Jílek, Martin Valchář, Jiří Holubek, Nataša Dlohožková, Josef Pomykáček, Oluše Matoušová, Jiřina Metyšová and Miroslav Protiva
    Noncataleptic neuroleptic agents: 2-(4-(2-(2-Chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yloxy)ethyl)piperazine-1-yl)ethanol and some related compounds
    1988, Vol. 53, Issue 11, pp. 2731–2741 [Abstract]
  • Zdena Koblicová, Jiří Holubek and Jan Trojánek
    Synthesis of stereoisomeric vincamines
    1988, Vol. 53, Issue 11, pp. 2722–2730 [Abstract]
  • Miroslav Kuchař, Eva Maturová, Bohumila Brunová, Jaroslava Grimová, Hana Tomková and Jiří Holubek
    Quantitative relations between structure and antiinflammatory activity of aryloxoalkanoic acids
    1988, Vol. 53, Issue 8, pp. 1862–1872 [Abstract]
  • Hana Hulinská, Zdeněk Polívka, Jiří Jílek, Karel Šindelář, Jiří Holubek, Emil Svátek, Oluše Matoušová, Miloš Buděšínský, Hana Frycová and Miroslav Protiva
    Experimental antiulcer agents: N-substituted 2-(4-methyl-1-piperazinyl)acetamides as pirenzepine models and some related compounds
    1988, Vol. 53, Issue 8, pp. 1820–1844 [Abstract]
  • Irena Červená, Jiří Holubek, Emil Svátek and Miroslav Protiva
    Potential antidepressants: 4-(Aminoalkoxy)thioxanthones
    1988, Vol. 53, Issue 6, pp. 1307–1316 [Abstract]
  • Zdeněk Polívka, Jiřina Metyšová, Martin Valchář and Miroslav Protiva
    Potential antidepressants: N-phenacyl derivatives of (E)-N-methyl-3-(6,11-dihydrodibenzo[b,e]thiepin-11-ylidene)propylamine
    1988, Vol. 53, Issue 4, pp. 884–888 [Abstract]
  • Jiří Jílek, Jiří Holubek, Emil Svátek, Jan Metyš, Hana Frycová, Josef Pomykáček and Miroslav Protiva
    Tricyclic analogues of the antiallergic agent oxatomide: 1-(3-(4-(10,11-Dihydro-5H-dibenzo[a,d]cycloheptene-5-yl)-1-piperazinyl)propyl)-1,3-dihydro-2H-benzimidazol-2-one and the related 6,11-dihydrodibenzo[b,e]thiepin, 4,9-dihydrothieno[2,3-c]-2-benzothiepin, and 10,11-dihydrodibenzo[b,f]thiepin derivatives
    1988, Vol. 53, Issue 4, pp. 870–883 [Abstract]
  • Vladimír Valenta, Hana Hulinská, Jiří Holubek, Antonín Dlabač, Jan Metyš, Hana Frycová and Miroslav Protiva
    N-substituted derivatives of 6,11-dihydrodibenzo[b,e]thiepin-11-amine and related compounds; Synthesis and pharmacological screening
    1988, Vol. 53, Issue 4, pp. 860–869 [Abstract]
  • Karel Šindelář, Zdeněk Šedivý, Marta Hrubantová, Martin Valchář, Jiřina Metyšová and Miroslav Protiva
    Synthesis of (2-(phenylthio)phenyl)acetamidines and related amidoximes as potential antidepressants
    1988, Vol. 53, Issue 2, pp. 381–388 [Abstract]
  • Zdeněk Vejdělek, Jiří Holubek, Miloš Buděšínský, Miroslav Ryska, Emil Svátek and Miroslav Protiva
    Reactions of 4-chloro-1-nitrobenzene with (3-chloro-4-methoxyphenyl)acetonitrile and (3,4-dimethoxyphenyl)acetonitrile; Synthesis of 8-chloro-1-methyl (and methylthiomethyl-6-(3,4-disubstituted phenyl)-4H-s-triazolo[4,3-a]-1,4-benzodiazepines
    1988, Vol. 53, Issue 2, pp. 361–372 [Abstract]
  • Karel Šindelář, Jiří Holubek, Oluše Matoušová, Emil Svátek, Martin Valchář, Antonín Dlabač, Nataša Dlohožková, Marta Hrubantová and Miroslav Protiva
    Aminoalkylidene and aminoalkyl derivatives of 6,11-dihydrodibenzo[b,e]thiepin-2- and -9-carbonitrile and 4,10-dihydrothieno[2,3-c]-1-benzothiepin-6-carbonitrile; Antidepressants with a new activity profile
    1988, Vol. 53, Issue 2, pp. 340–360 [Abstract]
  • Zdeněk Vejdělek, Jan Metyš, Jiří Holubek, Miloš Buděšínský, Emil Svátek, Oluše Matoušová and Miroslav Protiva
    Potentional anxiolytics and hypnotics: 1-(Alkanesulfonamidoalkyl)-6-aryl-8-halogeno-s-triazolo[4,3-a]-1,4-benzodiazepines and related compounds
    1988, Vol. 53, Issue 1, pp. 132–144 [Abstract]
  • Vladimír Valenta, Jiří Holubek, Emil Svátek and Miroslav Protiva
    Synthesis of 4-methoxyphenoxyacetic and 3,4,5-trimethoxyphenoxyacetic acid amides and hydrazides as potential neurotropic and cardiovascular agents
    1987, Vol. 52, Issue 12, pp. 3013–3023 [Abstract]
  • Antonín Černý, Jiří Křepelka, Karel Řežábek, Maria Frühaufová, Václav Plaisner and Jiří Holda
    Some dopaminergically active esters of N-[(5R,8S,10R)-6-propyl-8-ergolinyl]carbamic acid with cancerogenicity manifestations
    1987, Vol. 52, Issue 12, pp. 2983–2990 [Abstract]
  • Zdeněk Polívka, Jiří Holubek, Miloš Buděšínský, Oluše Matoušová, Emil Svátek, Jan Metyš and Miroslav Protiva
    Potential antihistamine agents: 4-(6,11-Dihydrodibenzo[b,e]thiepin-11-ylidene)-1-methyltetrahydrothiopyranium iodide and similar sulfonium salts derived from related tricyclic systems
    1987, Vol. 52, Issue 11, pp. 2758–2774 [Abstract]
  • Irena Červená, Jiří Holubek, Emil Svátek, Martin Valchář and Miroslav Protiva
    Potential antidepressants: 3-Methyl-6-dimethylamino-1,2-diphenylhexan-3-ol and related compounds
    1987, Vol. 52, Issue 10, pp. 2564–2571 [Abstract]
  • Zdeněk Vejdělek, Jiří Holubek, Miroslav Ryska, Ivan Koruna, Emil Svátek, Miloš Buděšínský and Miroslav Protiva
    Reactions of 4-chloro-1-nitrobenzene with o-substituted phenylacetonitriles; Synthesis of 8-chloro-1-methyl(and methylthiomethyl)-6-(2-substituted phenyl)-4H-s-triazolo[4,3-a]-1,4-benzodiazepines
    1987, Vol. 52, Issue 10, pp. 2545–2563 [Abstract]
  • Vladimír Valenta, Jiří Holubek, Emil Svátek, Vladimír Miller, Marie Vlková and Miroslav Protiva
    2-Diethylaminoethyl esters of 1,3-disubstituted propane-2-carboxylic acids
    1987, Vol. 52, Issue 10, pp. 2534–2544 [Abstract]
  • Karel Šindelář, Miloš Buděšínský, Tomáš Vaněk, Jiří Holubek, Emil Svátek, Oluše Matoušová, Charles Wayne Rees and Miroslav Protiva
    Reaction of 6,11-dihydrodibenzo[b,e]thiepin-11-carbonitrile with 1,2-dibromoethane, a reinvestigation. Formation of 11,12-dihydro-6H-6,12-methanodibenzo[b,f]thiocin-12-carbonitrile
    1987, Vol. 52, Issue 9, pp. 2281–2294 [Abstract]
  • Miroslav Protiva, Jiří Jílek, Miroslav Rajšner, Karel Šindelář, Václav Bártl, Miroslav Ryska, Ivan Koruna, Jiří Holubek, Emil Svátek, Jiřina Metyšová, Antonín Dlabač, Josef Pomykáček and František Mikšík
    Fluorinated tricyclic neuroleptics with prolonged action: derivatives and analogues of 2-(4-(7-fluoro-2-isopropyl-10,11-dihydrodibenzo[b,f]thiepin-11-yl)-piperazine-1-yl)ethanol
    1987, Vol. 52, Issue 7, pp. 1811–1833 [Abstract]
  • Zdeněk Polívka, Irena Lichá, Petr Taufmann, Emil Svátek, Jiří Holubek and Miroslav Protiva
    Synthesis of 3-(6,11-dihydrodibenzo[b,e]thiepin-11-ylidene)propanoic acid and related compounds
    1987, Vol. 52, Issue 6, pp. 1566–1582 [Abstract]
  • Antonín Černý, Jan Beneš, Jaroslav Vachek, Milan Pešák, Josef Stuchlík, Milan Stuchlík, Petr Sedmera, Miroslav Flieger and Jindřich Vokoun
    Solvolysis of some 1-(8α-ergolinyl)-3,3-diethylureas and their salts
    1987, Vol. 52, Issue 5, pp. 1331–1339 [Abstract]
  • Vladimír Valenta, Jiří Holubek and Miroslav Protiva
    4-Substituted 1-(1-(2-(arylthio)-5-halogenophenyl)ethyl)piperazines; Synthesis and biological screening
    1987, Vol. 52, Issue 4, pp. 1062–1072 [Abstract]
  • Vojtěch Kmoníček, Jiří Holubek, Emil Svátek, Jiřina Metyšová and Miroslav Protiva
    2-(tert.amino)-11-(4-methylpiperazino)dibenzo[b,f]thiepins and their 10,11-dihydro derivatives; Synthesis and neuroleptic activity
    1987, Vol. 52, Issue 3, pp. 793–803 [Abstract]
  • Zdeněk Veselý, Jiří Holubek and Jan Trojánek
    Reactions in the series of substituted isoindolo[1,2-b][3]-benzazepin-5-ones
    1987, Vol. 52, Issue 1, pp. 233–241 [Abstract]
  • Miroslav Kuchař, Bohumila Brunová, Jaroslava Grimová, Stanislav Vaněček and Jiří Holubek
    Synthesis of cyclohexylaliphatic acids and their pharmacological properties
    1986, Vol. 51, Issue 12, pp. 2896–2908 [Abstract]
  • Karel Šindelář, Jiří Holubek, Miroslav Ryska, Ivan Koruna and Miroslav Protiva
    5-Substituted and 5,7-disubstituted 5,7-dihydrodibenzo[c,e]thiepins and the corresponding S-oxygenated compounds: Alkylamines, carboxylic acids, and carboxamides; synthesis and pharmacological screening
    1986, Vol. 51, Issue 12, pp. 2848–2868 [Abstract]
  • Miroslav Kuchař, Bohumila Brunová, Jaroslava Grimová, Václav Rejholec and Václav Čepelák
    On the quantitative relations between structure and antiaggregation activity of ω-aryl-ω-oxoalkanoic acids
    1986, Vol. 51, Issue 11, pp. 2617–2625 [Abstract]
  • Miroslav Protiva, Jiří Jílek, Irena Červená, Josef Pomykáček, Václav Bártl, Antonín Dlabač, Martin Valchář, Jiřina Metyšová, Jiří Holubek and Emil Svátek
    Noncataleptic neuroleptic agents: 4-Substituted 1-(2-chloro-7-fluoro-10,11-dihydrodibenzo[b,f]thiepin-10-yl)piperazines and related compounds
    1986, Vol. 51, Issue 11, pp. 2598–2616 [Abstract]
  • Jiří Jílek, Martin Valchář, Josef Pomykáček, Antonín Dlabač and Miroslav Protiva
    Noncataleptic neuroleptic agents: Synthesis of some esters of 2-chloro-10-(4-(2-hydroxyethyl)piperazino)-10,11-dihydrodibenzo[b,f]thiepin
    1986, Vol. 51, Issue 7, pp. 1503–1508 [Abstract]
  • Jiří Křepelka, Antonín Černý, Rudolf Kotva, Jaroslav Vachek and Milan Mělka
    Some derivatives of 5-(2-amino-6-hydroxy-4-oxo-3,4-dihydro-5-pyrimidinyl)pentanoic acid
    1986, Vol. 51, Issue 5, pp. 1140–1149 [Abstract]
  • Vojtěch Kmoníček, Emil Svátek, Jiří Holubek and Miroslav Protiva
    Synthesis of potential neuroleptics and tranquillizers: 2-(tert.Amino)-9-(3-dimethylaminopropylidene)thioxanthenes
    1986, Vol. 51, Issue 4, pp. 937–947 [Abstract]
  • Miroslav Protiva, Jiří Jílek, Miroslav Rajšner, Josef Pomykáček, Miroslav Ryska, Jiří Holubek, Emil Svátek and Jiřina Metyšová
    Fluorinated tricyclic neuroleptics with prolonged action: 7-Fluoro-11-[4-(2-hydroxyethyl)piperazino]-2-isopropyl-10,11-dihydrodibenzo[b,f]thiepin
    1986, Vol. 51, Issue 3, pp. 698–722 [Abstract]
  • Michal P. Nemeryuk, Andrej L. Sedov, Tamara S. Safonova, Antonín Černý and Jiří Křepelka
    Transformations of substituted 5-aminopyrimidines under conditions of the diazotization
    1986, Vol. 51, Issue 1, pp. 215–233 [Abstract]
  • Miroslav Protiva, Antonín Dlabač, Martin Valchář, Stanislav Wildt, Irena Červená and Zdeněk Šedivý
    Potential noncataleptic neuroleptic agents; 2,6-Dichloro-, 2,7-dichloro- and 2,8-dichloro-10-piperazino-10,11-dihydrodibenzo[b,f]thiepins
    1986, Vol. 51, Issue 1, pp. 156–166 [Abstract]
  • Irena Červená, Jiří Holubek, Emil Svátek, Jiřina Metyšová, Martin Valchář, Antonín Dlabač, Stanislav Wildt and Miroslav Protiva
    6-Substituted and 2-chloro-6-substituted 10-piperazino-10,11-dihydrodibenzo[b,f]thiepins as potential antidepressants; Synthesis and pharmacology
    1986, Vol. 51, Issue 1, pp. 141–155 [Abstract]
  • Jiří Jílek, Jiří Holubek, Emil Svátek, Jiřina Metyšová, Josef Pomykáček, Zdeněk Šedivý and Miroslav Protiva
    Potential metabolites of the neuroleptic agents belonging to the 8-methylthio-10-piperazino-10,11-dihydrodibenzo[b,f]thiepin series; Synthesis of 2-hydroxy and 3-hydroxy derivatives
    1985, Vol. 50, Issue 10, pp. 2179–2190 [Abstract]
  • Miroslav Protiva, Zdeněk Šedivý, Jiří Holubek, Emil Svátek and Jiří Němec
    Cyclic amidines derived from benz[c,d]indole and 4,5-dihydro-3H-1-benzazepine including some related compounds: Synthesis and pharmacological screening
    1985, Vol. 50, Issue 8, pp. 1888–1898 [Abstract]
  • Karel Šindelář, Jiří Holubek, Emil Svátek, Miroslav Ryska, Martin Valchář and Miroslav Protiva
    Butaclamol-like neuroleptic agents: Synthesis of 1-(11H-dibenz[b,f]-1,4-oxathiepin-11-yl)methyl-4-isobutylpiperidin-4-ol and of some related compounds
    1985, Vol. 50, Issue 7, pp. 1484–1497 [Abstract]
  • Zdeněk Polívka, Jiří Holubek, Emil Svátek, Jan Metyš and Miroslav Protiva
    Synthesis of the semi-rigid analogues of prothiadene and dithiadene as potential antidepressant and antihistamine agents: 11-[2-(Dimethylaminomethyl)cyclohexylidene]-6,11-dihydrodibenzo[b,e]thiepins and 4-[2-(dimethylaminomethyl)cyclohexylidene]-4,9-dihydrothieno-[2,3-c]-2-benzothiepins
    1985, Vol. 50, Issue 5, pp. 1078–1088 [Abstract]
  • Vladimír Valenta, Zdeněk Prošek, Jiřina Metyšová, Martin Valchář, Antonín Dlabač and Miroslav Protiva
    Cataleptic and noncataleptic neuroleptic agents: Synthesis and pharmacology of 4-(2-chloro and 8-chloro substituted 10,11-dihydrodibenzo[b,f]thiepin-10-yl)piperazine-1-ylalkyl ethers and sulfides
    1985, Vol. 50, Issue 5, pp. 1070–1077 [Abstract]
  • Jan Šmidrkal, Jiří Holubek and Jan Trojánek
    The synthesis of 2,3,7,8-bismethylenedioxy-11-methoxy-5-methylbenzo[c]phenanthridinium chloride
    1985, Vol. 50, Issue 4, pp. 984–990 [Abstract]
  • Jan Šmidrkal, Jiří Holubek, Jiří Šlanger and Jan Trojánek
    Attempts at the synthesis of 11-methoxysubstituted benzo[c]phenantridines
    1985, Vol. 50, Issue 4, pp. 861–868 [Abstract]
  • Jiří Jílek, Jiří Holubek, Emil Svátek, Jiří Schlanger, Josef Pomykáček and Miroslav Protiva
    Highly polar potential metabolites of the neuroleptic agent oxyprothepin: Synthesis of 2-hydroxy-8-methylsulfonyl and 3-hydroxy-8-methylsulfonyl derivatives of 10-[4-(3-hydroxypropyl)piperazino]-10,11-dihydrodibenzo[b,f]thiepin
    1985, Vol. 50, Issue 2, pp. 519–537 [Abstract]
  • Karel Šindelář, Jiří Holubek, Jiří Schlanger, Antonín Dlabač, Martin Valchář and Miroslav Protiva
    Synthesis of spiro(piperidine-4,6'-dibenz[b,e]-1,4-oxathiepin) and its 1-methyl derivative as potential antidepressant agents
    1985, Vol. 50, Issue 2, pp. 503–509 [Abstract]
  • Antonín Černý, Jiří Křepelka, Viktor Zikán, Drahuše Vlčková, Jaroslav Vachek, Jiří Holubek, Karel Řežábek, Maria Frühaufová, Miroslav Šeda, Jana Chlebounová and Otakar Marhan
    Some 6-substituted 1-[(5R,8S,10R)-8-ergolinyl]-3,3-diethylureas
    1984, Vol. 49, Issue 12, pp. 2828–2836 [Abstract]
  • Zdeněk Vejdělek, Jan Metyš, Jiří Holubek, Emil Svátek and Miroslav Protiva
    Potential antiparkinsonic agents: Synthesis and pharmacology of some 4-fluoro-4'-halogen'benzhydryl 2-(N,N-disubstituted amino)ethyl ethers
    1984, Vol. 49, Issue 11, pp. 2649–2660 [Abstract]
  • Karel Šindelář, Jiří Holubek, Miroslav Ryska, Antonín Dlabač, Martin Valchář, Jiřina Metyšová and Miroslav Protiva
    Tricyclic compounds containing two chalcogen atoms in the central seven-membered rings as potential drugs: Synthesis of 3-chloro-6-(1-methyl-4-piperidyl)-6H-dibenz[b,e]-1,4-oxathiepin and 6-oxodibenz[b,e]-1,4-oxathiepin-2-acetic acid
    1984, Vol. 49, Issue 11, pp. 2531–2540 [Abstract]
  • Václav Bártl, Karel Šindelář, Vladimír Valenta, Jiří Holubek, Emil Svátek, Jiří Schlanger, Antonín Dlabač, Jiřina Metyšová and Miroslav Protiva
    Potential antipsychotic agents: 2-Chloro- and 2-methyl-11-(2-piperazinoethoxy)-6,11-dihydrodibenzo[b,e]thiepins and some related compounds; Synthesis and pharmacology
    1984, Vol. 49, Issue 11, pp. 2520–2530 [Abstract]
  • Václav Bártl, Jiří Jílek, Jiřina Metyšová, Martin Valchář, Antonín Dlabač, Stanislav Wildt and Miroslav Protiva
    Neuroleptic 2-chloro-11-(2-piperazineethoxy)-10,11-dihydrodibenzo[b,f]thiepins: Synthesis and pharmacology
    1984, Vol. 49, Issue 8, pp. 1810–1815 [Abstract]
  • Václav Bártl, Antonín Dlabač, Martin Valchář and Miroslav Protiva
    11-(4-Piperidylidene)-6,11-dihydrodibenzo[b,e]thiepins as potential antipsychotic agents; Synthesis and pharmacology
    1984, Vol. 49, Issue 8, pp. 1800–1809 [Abstract]
  • Karel Šindelář, Jiří Holubek, Miroslav Ryska, Emil Svátek, Antonín Dlabač, Martin Valchář and Miroslav Protiva
    Analogues of the neuroleptic agent isobutaclamol: Stereoisomeric 3b,4,5,6,7,9,9a,10-octahydro-[1]benzothiepino[2,3,4-ed]pyrido[2,1-a]isoquinolin-5-ols and some related compounds
    1984, Vol. 49, Issue 4, pp. 1021–1038 [Abstract]
  • Vladimír Valenta, Antonín Dlabač, Martin Valchář and Miroslav Protiva
    α-Benzyldopamine and some related compounds: Synthesis and pharmacological screening
    1984, Vol. 49, Issue 4, pp. 1002–1008 [Abstract]
  • Jiří Urban, Antonín Dlabač, Martin Valchář and Miroslav Protiva
    Potential noncataleptic neuroleptic agents: 2,3-Dichloro-10-[4-(2-hydroxyethyl)piperazino]-10,11-dihydrobenzo[b,f]thiepin
    1984, Vol. 49, Issue 4, pp. 992–1001 [Abstract]
  • Zdeněk Polívka, Jiří Holubek, Emil Svátek, Jan Metyš and Miroslav Protiva
    Potential hypnotics and anxiolytics: Synthesis of 2-bromo-4-(2-chlorophenyl)-9-[4-(2-methoxyethyl)piperazino]-6H-thieno[3,2,4-triazolo[4,3-a]-1,4-diazepine and of some related compounds
    1984, Vol. 49, Issue 3, pp. 621–636 [Abstract]
  • Jiří Jílek, Josef Pomykáček, Jiří Holubek, Emil Svátek, Miroslav Ryska, Jiří Protiva and Miroslav Protiva
    Reactions of 4,4'-disubstituted diphenyl sulfides with chloroacetyl chloride and aluminium chloride
    1984, Vol. 49, Issue 3, pp. 603–620 [Abstract]
  • Miroslav Kuchař, Bohumila Brunová, Václav Rejholc, Magda Jelínková, Jiří Holubek and Oldřich Němeček
    Quantitative relations between structure and activation of fibrinolysis in selected series of arylaliphatic acids
    1984, Vol. 49, Issue 1, pp. 122–136 [Abstract]
  • Zdeněk Polívka, Jiří Jílek, Jiří Holubek, Emil Svátek, Antonín Dlabač, Martin Valchář and Miroslav Protiva
    Noncataleptic neuroleptic agents: 2-Halogeno-8-isopropyl-10-piperazino-10,11-dihydrodibenzo[b,f,]thiepins
    1984, Vol. 49, Issue 1, pp. 86–109 [Abstract]
  • Zdeněk Polívka, Jiří Holubek, Jan Metyš, Zdeněk Šedivý and Miroslav Protiva
    Potential hypnotics and anxiolytics: 8-Chloro-6-(2-chlorophenyl)-1-[4-(2-methoxyethyl)piperazino]-methyl-4H-s-triazolo[4,3-a]-1,4-benzodiazepine and related compounds
    1983, Vol. 48, Issue 12, pp. 3433–3443 [Abstract]
  • Zdeněk Polívka, Martin Valchář and Miroslav Protiva
    Potential noncataleptic neuroleptic agents: Synthesis and pharmacology of 7-chloro-4-[4-(2-hydroxyethyl)piperazino]-4,5-dihydrothieno[2,3-b]-1-benzothiepin
    1983, Vol. 48, Issue 10, pp. 2970–2976 [Abstract]
  • František Brtník, Ivan Krejčí, Běla Kupková, Pavel Hrbas, Jana Škopková, Tomislav Barth and Karel Jošt
    Vasopressin analogues with effect on central nervous system: Synthesis and biological properties
    1983, Vol. 48, Issue 10, pp. 2862–2873 [Abstract]
  • Zdeněk Polívka, Miroslav Ryska, Jiří Holubek, Emil Svátek, Jan Metyš and Miroslav Protiva
    Potential hypnotics and anxiolytics in the 4H-s-triazolo[4,3-a]-1,4-benzodiazepine series: 8-Chloro-6-(2-chlorophenyl)-1-[4-(2-methoxyethyl)piperazino]-4H-s-triazolo[4,3-a]-1,4-benzodiazepine and some related compounds
    1983, Vol. 48, Issue 8, pp. 2395–2410 [Abstract]
  • Karel Šindelář, Jiří Holubek, Miroslav Ryska, Emil Svátek, Jiří Urban and Miroslav Protiva
    11-(Dimethylaminoalkyl)-6,11-dihydrodibenzo[b,e]thiepin-11-carbonitriles and some related compounds
    1983, Vol. 48, Issue 7, pp. 1898–1909 [Abstract]
  • Antonín Černý, Viktor Zikán, Drahuše Vlčková, Jan Beneš, Jiří Holubek, Karel Řežábek, Marie Aušková and Jiří Křepelka
    (5R,8S,10R)-6-Alkyl-8-ergolinecarboxylic acids and some of their derivatives
    1983, Vol. 48, Issue 5, pp. 1483–1488 [Abstract]
  • Zdeněk Polívka, Jiří Holubek, Emil Svátek, Antonín Dlabač, Dušan Půček, Zdeněk Šedivý and Miroslav Protiva
    3-(4-Methylpiperazino)dibenzo[b,f]-1,2,4-triazolo[4,3-d]-1,4-thiazepine and its 6-chloro and 12-chloro derivatives; Synthesis and pharmacology
    1983, Vol. 48, Issue 5, pp. 1465–1476 [Abstract]
  • Vladimír Valenta, Jiří Holubek, Emil Svátek, Antonín Dlabač, Marie Bartošová and Miroslav Protiva
    α-(4-Tolyl)dopamine, derivatives and analogues; Synthesis and pharmacological screening
    1983, Vol. 48, Issue 5, pp. 1447–1464 [Abstract]
  • Jan Beneš, Antonín Černý, Vladimír Miller and Stanislav Kudrnáč
    Epimerization of esters of stereoisomeric 8-ergolinecarboxylic acids on carbon C(8)
    1983, Vol. 48, Issue 5, pp. 1333–1340 [Abstract]
  • Jiří Křepelka, Vladimír Pouzar, Jiří Schlanger, Jiří Holubek, Jiří Körbl, Fedir Jančik and Rudolf Kotva
    Oxidative transformations of some pyrimidine derivatives into oxazolidine derivatives
    1983, Vol. 48, Issue 4, pp. 1212–1223 [Abstract]
  • Karel Šindelář, Jiří Holubek, Miroslav Ryska, Emil Svátek, Jiří Urban, Jaroslava Grimová, Irena Červená, Marta Hrubantová and Miroslav Protiva
    Dibenzo[b,f]thiepin-10-carbonitrile, its 10,11-dihydro derivative, some transformation products and related compounds
    1983, Vol. 48, Issue 4, pp. 1187–1211 [Abstract]
  • Václav Bártl, Jiří Holubek, Emil Svátek, Marie Bartošová and Miroslav Protiva
    Potential anticonvulsants: Substituted N-benzylidene derivatives of 10-(4-aminopiperazino)-10,11-dihydrodibenzo[b,f]thiepins
    1983, Vol. 48, Issue 4, pp. 1173–1186 [Abstract]
  • Miroslav Kuchař, Václav Rejholec, Zdeněk Roubal and Oluše Matoušová
    The effects of lipophilicity on the inhibition of denaturation of serum albumin and on the activation of fibrinolysis observed with a series of benzyloxyarylaliphatic acids
    1983, Vol. 48, Issue 4, pp. 1077–1088 [Abstract]
  • Jiří Jílek, Josef Pomykáček, Zdeněk Prošek, Jiří Holubek, Emil Svátek, Jiřina Metyšová, Antonín Dlabač and Miroslav Protiva
    8-Chloro and 8-methylthio derivatives of 10-piperazino-10,11-dihydrodibenzo[b,f]thiepins; New compounds and new procedures
    1983, Vol. 48, Issue 3, pp. 906–927 [Abstract]
  • Zdeněk Polívka, Miroslav Rajšner, Jan Metyš, Jiří Holubek, Emil Svátek, Miroslav Ryska and Miroslav Protiva
    Antiaminic agents derived from thieno[2,3-c]-2-benzothiepin: 4-(1-Methyl-4-piperidylidene)-4,9-dihydrothieno[2,3-c]-2-benzothiepin and some related compounds
    1983, Vol. 48, Issue 2, pp. 623–641 [Abstract]
  • Jiří Křepelka, Drahuše Vlčková, Jiří Holubek and Jiří Roubík
    8-Substitution derivatives of D-6-methylergoline-I
    1983, Vol. 48, Issue 1, pp. 312–318 [Abstract]
  • Jiří Křepelka, Jan Beneš, Vladimír Pouzar, Jaroslav Vachek and Jiří Holubek
    Some 2-substitution derivatives of 5-(4-oxo-6-hydroxy-3,4-dihydro-5-pyrimidinyl)pentanoic acid
    1983, Vol. 48, Issue 1, pp. 304–311 [Abstract]
  • Rudolf Kotva, Jaroslav Vachek and Jiří Křepelka
    Some derivatives of 4-[(2-amino-6-hydroxy-4-oxo-3,4-dihydro-5-pyrimidinyl)methyl] benzoic acid
    1983, Vol. 48, Issue 1, pp. 299–303 [Abstract]
  • Miloš Beran, Antonín Černý, Jiří Křepelka and Jaroslav Vachek
    Substituted ω-(4-oxo-3,4-dihydro-5-pyrimidinyl) alkanoic acids, their derivatives and analogues
    1983, Vol. 48, Issue 1, pp. 292–298 [Abstract]
  • Miroslav Rajšner, Jan Metyš, Jiří Holubek and Miroslav Protiva
    Potential antidepressants: Some N-substituted derivatives of (E)-11-(3-methylaminopropylidene)-6,11-dihydrodibenzo[b,e]thiepin
    1983, Vol. 48, Issue 1, pp. 163–172 [Abstract]
  • Karel Šindelář, Jiřina Metyšová, Jiří Holubek, Emil Svátek, Miroslav Ryska and Miroslav Protiva
    Fluorinated tricyclic neuroleptics with prolonged action: 3-Fluoro-10-[4-(2-hydroxyethyl)piperazino]-10,11-dihydrodibenzo[b,f]thiepins with less common substituents in position 8
    1983, Vol. 48, Issue 1, pp. 144–155 [Abstract]
  • Miloš Beran, Jan Beneš and Jiří Křepelka
    Derivatives of 3-(D-6-methyl-8β-ergolin-I-yl)propanoic acid
    1982, Vol. 47, Issue 12, pp. 3432–3436 [Abstract]
  • Zdeněk Vejdělek, Jiří Holubek, Marie Bartošová and Miroslav Protiva
    4-(Aminoacylamido)-s-hydrindacenes and related compounds: Synthesis and pharmacological screening
    1982, Vol. 47, Issue 12, pp. 3297–3305 [Abstract]
  • Miroslav Protiva, Zdeněk Šedivý, Jiří Holubek, Emil Svátek, Jiřina Metyšová and Marie Bartošová
    Potential psychotropic and antihistamine agents: 1- and 3-alkyl-9-(3-dimethylaminopropylidene)-thioxanthenes and 3-alkyl-11-piperazino-10,11-dihydrodibenzo[b,f]thiepins
    1982, Vol. 47, Issue 11, pp. 3134–3147 [Abstract]
  • Karel Šindelář, Jiří Holubek, Emil Svátek, Miroslav Ryska, Antonín Dlabač, Jiřina Metyšová and Miroslav Protiva
    Tricyclic psychotropic agents containing two chalcogen atoms in the central ring: 2-Fluoro-8-substituted 6-(4-piperidyl)-6H-dibenz[b,e]-1,4-oxathiepins
    1982, Vol. 47, Issue 11, pp. 3114–3133 [Abstract]
  • Miroslav Protiva, Karel Šindelář, Vladimír Valenta, Jiří Holubek, Emil Svátek, Miroslav Ryska, Jiří Schlanger, Jiří Urban and Marta Hrubantová
    Reactions of 11-chloro-11-phenyl-6,11-dihydrodibenzo[b,e]-thiepin with piperidine and some further nucleophiles
    1982, Vol. 47, Issue 11, pp. 3094–3113 [Abstract]
  • Karel Šindelář, Jiřina Metyšová, Jiří Holubek, Emil Svátek, Jiří Protiva and Miroslav Protiva
    Tricyclic psychotropic agents containing two chalcogen atoms in the central ring: 8-Substituted 6-(4-piperidyl)-6H-dibenz[b,e]-1,4-oxathiepins
    1982, Vol. 47, Issue 11, pp. 3077–3093 [Abstract]
  • Josef Hájíček, Jiří Holubek and Jan Trojánek
    Synthesis of 4,4- and 5,5-disubstituted 4,5-dihydro-6H-canthin-6-ones
    1982, Vol. 47, Issue 10, pp. 2749–2762 [Abstract]
  • Rudolf Kotva, Jiří Křepelka and Jaroslav Vachek
    2-Substituted derivatives of 5-(4-oxo-3,4-dihydro-5-pyrimidinyl)pentanoic acid
    1982, Vol. 47, Issue 9, pp. 2525–2529 [Abstract]
  • Miroslav Kuchař, Václav Rejholec, Bohumila Brunová, Jaroslava Grimová, Oluše Matoušová, Oldřich Němeček and Hana Čepeláková
    Benzyloxyarylaliphatic acids: Synthesis and quantitative relations between structure and antiinflammatory activity
    1982, Vol. 47, Issue 9, pp. 2514–2524 [Abstract]
  • Jiří Křepelka, Iva Vančurová, Jiří Holubek, Milan Mělka and Karel Řežábek
    Derivatives of benzo(c)fluorene: II. Synthesis and biological effect of basic ethers of 7-oxo-7H-benzo(c)fluorene
    1982, Vol. 47, Issue 7, pp. 1856–1866 [Abstract]
  • Jan Beneš and Jiří Holubek
    1,2-Fused derivatives of ergoline
    1982, Vol. 47, Issue 6, pp. 1641–1644 [Abstract]
  • Jan Beneš and Jiří Holubek
    Wittig type reactions of 2-formylated derivatives of 6-methylergoline - I
    1982, Vol. 47, Issue 6, pp. 1636–1640 [Abstract]
  • Karel Šindelář, Jiří Holubek, Emil Svátek, Miroslav Ryska, Antonín Dlabač and Miroslav Protiva
    Tricyclic psychotropic agents containing two chalcogen atoms in the central ring: Synthesis of 6-(aminoalkyl) derivatives of 6H-dibenz[b,e]-1,4-oxathiepin
    1982, Vol. 47, Issue 5, pp. 1367–1381 [Abstract]
  • Jiří Křepelka, Jiří Roubík, Jiří Holubek and Iva Vančurová
    5-, 6- And 7-substitution derivatives of 7-oxo-7H-benzo(c)fluorene
    1982, Vol. 47, Issue 4, pp. 1258–1266 [Abstract]
  • Jiří Křepelka, Iva Vančurová and Jiří Holubek
    Reactions of 4-aryl-1-methoxynaphtalene-2,3-dicarboxylic acid anhydrides and naphtho(2,3-c)furan-1-(3H)-one derivatives with hydrazines
    1982, Vol. 47, Issue 4, pp. 1252–1257 [Abstract]
  • Karel Šindelář, Jiří Holubek, Miroslav Ryska, Antonín Dlabač, Jiřina Metyšová, Emil Svátek, Marta Hrubantová, Jiří Protiva and Miroslav Protiva
    Tricyclic psychotropic agents containing two chalcogen atoms in the central ring: Derivatives of 11H-dibenz[b,f]-1,4-oxathiepin
    1982, Vol. 47, Issue 3, pp. 967–983 [Abstract]
  • Jiří Křepelka, Iva Vančurová, Jiří Holubek, Jiří Roubík and Drahuše Vlčková
    Syntheses and antineoplastic effects of some N-substituted imides of 1-substituted 4-aryl-naphthalene-2,3-dicarboxylic acids
    1982, Vol. 47, Issue 1, pp. 304–314 [Abstract]
  • Karel Šindelář, Jiří Holubek, Miroslav Ryska, Emil Svátek, Antonín Dlabač, Marta Hrubantová and Miroslav Protiva
    Tricyclic psychotropic agents containing two chalcogen atoms in the central ring: Synthesis of 11-(dimethylaminoalkyl) derivatives of 11H-dibenzo[b,e]-1,4-dioxepin and 11H-dibenzo[b,e]-1,4-dithiepin
    1982, Vol. 47, Issue 1, pp. 72–87 [Abstract]
  • Miroslav Protiva, Zdeněk Šedivý, Josef Pomykáček, Václav Bártl, Jiří Holubek and Emil Svátek
    Potential metabolites of the noncataleptic neuroleptics: Synthesis of 2-chloro-6-hydroxy(and methoxy)-10-[4-(2-hydroxyethyl)piperazino]-10,11-dihydrodibenzo[b,f]thiepin
    1981, Vol. 46, Issue 9, pp. 2245–2253 [Abstract]
  • Zdeněk Vejdělek, Jiří Holubek, Marie Bartošová and Miroslav Protiva
    1-(4-Cyclopentylphenyl)ethylamine and derivatives: Synthesis and pharmacological screening
    1981, Vol. 46, Issue 9, pp. 2234–2244 [Abstract]
  • Zdeněk Polívka, Jiří Holubek, Emil Svátek, Jiřina Metyšová and Miroslav Protiva
    Fluorinated tricyclic neuroleptics: Synthesis and pharmacology of 2-chloro-8-fluoro-4-(4-methylpiperazino)-4,5-dihydrothieno[2,3-b]-1-benzothiepin
    1981, Vol. 46, Issue 9, pp. 2222–2233 [Abstract]
  • Rudolf Kotva, Jiří Křepelka, Karel Řežábek and Jaroslav Vachek
    4-(ω-(2-Amino-6-hydroxy-4-oxo-3,4-dihydro-5-pyrimidinyl)alkyl)benzoic acids with an antineoplastic effect
    1981, Vol. 46, Issue 9, pp. 2217–2221 [Abstract]
  • Jiří Křepelka, Iva Vančurová, Jiří Holubek and Jiří Roubík
    Hydrolytic products of 4-aryl-2,3-dicyano-1-naphthol derivatives
    1981, Vol. 46, Issue 9, pp. 2207–2216 [Abstract]
  • Jiří Křepelka and Jiří Holubek
    The synthesis of model lactones of cyclolignan type
    1981, Vol. 46, Issue 9, pp. 2123–2128 [Abstract]
  • Jiří Křepelka, Jiří Roubík and Jiří Holubek
    1-Substitution derivatives of 4-aryl-2,3-dibromo-1-naphthol
    1981, Vol. 46, Issue 9, pp. 2116–2122 [Abstract]
  • Miroslav Protiva, Karel Šindelář, Zdeněk Šedivý, Jiří Holubek and Marie Bartošová
    Potential metabolites of tricyclic neuroleptics: 3,7-Dimethoxy and 7,8-dimethoxy derivatives of 10-(4-methylpiperazino)-10,11-dihydrodibenzo[b,f]thiepin
    1981, Vol. 46, Issue 8, pp. 1808–1817 [Abstract]
  • Miroslav Protiva, Karel Šindelář, Jiřina Metyšová, Jiří Holubek, Miroslav Ryska, Emil Svátek, Zdeněk Šedivý and Josef Pomykáček
    Fluorinated tricyclic neuroleptics with prolonged action: 3-Fluoro-8-halogeno derivatives of 10-piperazino-10,11-dihydrodibenzo[b,f]thiepins
    1981, Vol. 46, Issue 8, pp. 1788–1799 [Abstract]
  • Jiří Křepelka, Iva Vančurová and Jiří Holubek
    Some derivatives of 4-aryl-2,3-dicyano-1-naphthol
    1981, Vol. 46, Issue 6, pp. 1523–1529 [Abstract]
  • Rudolf Kotva, Jiří Křepelka, Antonín Černý, Vojtěch Pujman and Miroslav Semonský
    Some 2-substituted derivatives of 5-(2-amino-6-hydroxy-4-oxo-3,4-dihydro-5-pyrimidinyl)pentanoic acid
    1981, Vol. 46, Issue 6, pp. 1397–1404 [Abstract]
  • Miroslav Protiva, Zdeněk Šedivý, Josef Pomykáček, Emil Svátek and Jiří Holubek
    Potential metabolites of the neuroleptic agent octoclothepin; Synthesis of 8-chloro-2,6-dihydroxy and 8-chloro-3,6-dihydroxy derivatives of 10-(4-methylpiperazino)-10,11-dihydrodibenzo[b,f]thiepin
    1981, Vol. 46, Issue 5, pp. 1199–1209 [Abstract]
  • Miroslav Kuchař, Bohumila Brunová, Václav Rejholec, Zdeněk Roubal and Oldřich Němeček
    The synthesis of arylpropionic acids and the quantitative relationship between the structure and the activation of fibrinolysis
    1981, Vol. 46, Issue 5, pp. 1173–1187 [Abstract]
  • Karel Šindelář, Jiří Holubek, Jan Metyš, Marie Bartošová and Miroslav Protiva
    Synthesis of 3-(2-alkoxyphenoxy)-2-methyl (or phenyl)propylamines as potential antidepressants
    1981, Vol. 46, Issue 3, pp. 597–606 [Abstract]
  • Zdeněk Vejdělek, Emil Svátek, Jiří Holubek, Jan Metyš, Marie Bartošová and Miroslav Protiva
    Synthesis and pharmacological screening of 1-[2-tert-aminoethyl]-8-fluoro-5-[4-fluorophenyl]-2,3,4,5-tetrahydro-1H-1-benzazepines, their 1-[aminoacetyl] analogues and 1-substituted 9-fluoro-6-[4-fluorophenyl]-5,6-dihydro-4H-s-triazolo[4,3-a]-1-benzazepines
    1981, Vol. 46, Issue 1, pp. 148–160 [Abstract]
  • Karel Šindelář, Miroslav Ryska, Jiří Holubek, Emil Svátek, Jiřina Metyšová, Jiří Protiva and Miroslav Protiva
    Fluorinated tricyclic neuroleptics with prolonged action: 3-Fluoro-8-trifluoromethyl derivatives of 10-(4-methylpiperazino)- and 10-[4-(2-hydroxyethyl)piperazino]-10,11-dihydrodibenzo-[b,f]thiepin
    1981, Vol. 46, Issue 1, pp. 118–140 [Abstract]
  • Zdeněk Vejdělek, Miroslav Rajšner, Antonín Dlabač, Miroslav Ryska, Jiří Holubek, Emil Svátek and Miroslav Protiva
    Psychotropic derivatives of 5-phenyl-7-chloro-1,3-dihydro-1,4-benzodiazepin-2-one and contribution to the synthesis of its 5-(2-chlorophenyl) analogue
    1980, Vol. 45, Issue 12, pp. 3593–3615 [Abstract]
  • Miroslav Semonský, Antonín Černý, Jiří Křepelka, Rudolf Kotva, Bohumil Kakáč, Jiří Holubek and Jaroslav Vachek
    Some ω-(2-amino-6-hydroxy-4-oxo-3,4-dihydro-5-pyrimidinyl) alkanoic acids, their derivatives and analogues
    1980, Vol. 45, Issue 12, pp. 3583–3592 [Abstract]
  • Jiří Křepelka, Viktor Zikán, Jiří Holubek and Miroslav Semonský
    Derivatives of 4-aryl-2,3-dihalogeno-1-naphthol
    1980, Vol. 45, Issue 10, pp. 2700–2705 [Abstract]
  • Jiří Křepelka, Jiří Holubek and Miroslav Semonský
    Esters of 4,4-bis(4-ethylphenyl)-2,3-dibromo-2-butenoic acid and 7-ethyl-4-(4-ethylphenyl)-2,3-dibromo-1-naphthol
    1980, Vol. 45, Issue 10, pp. 2695–2699 [Abstract]
  • Irena Červená, Marta Hrubantová, Emil Svátek, Jiří Holubek, Miroslav Ryska, Jiřina Metyšová and Miroslav Protiva
    Fluorinated analogues of tricyclic neuroleptics: 6,9-difluoro derivative of 10-(4-methylpiperazino)-10,11-dihydrodibenzo[b,f]thiepin
    1980, Vol. 45, Issue 10, pp. 2688–2694 [Abstract]
  • Miroslav Kuchař, Bohumila Brunová, Zdeněk Roubal, Jiří Schlanger and Oldřich Němeček
    Synthesis of arylacetic acids and their effect on activation of fibrinolysis. Quantitative relations between structure and biological activity
    1980, Vol. 45, Issue 5, pp. 1401–1409 [Abstract]
  • Karel Šindelář, Emil Svátek, Jiří Holubek, Miroslav Ryska, Jiřina Metyšová, Zdeněk Šedivý and Miroslav Protiva
    Fluorinated analogues of the tricyclic neuroleptics; 7-Fluoro and 7-trifluoromethyl derivative of 10-(4-methylpiperazino)-10,11-dihydrodibenzo[b,f]thiepin
    1980, Vol. 45, Issue 4, pp. 1086–1098 [Abstract]
  • Jiří Křepelka, Jiří Holubek and Miroslav Semonský
    Some condensation products of ergoline - I Derivatives with ketones
    1980, Vol. 45, Issue 3, pp. 755–760 [Abstract]
  • Zdeněk Buděšínský, Josef Vavřina, Leon Langšádl and Jiří Holubek
    On the synthesis of 4- and 5-pyrimidinyl-diphenyl-(1-imidazolyl)methanes and their antifungal activity
    1980, Vol. 45, Issue 2, pp. 539–547 [Abstract]
  • Karel Šindelář, Jiří Holubek, Emil Svátek and Miroslav Protiva
    Synthesis of 3-chloro-5-(4-methylpiperazino)-6,7-dihydro-5H-dibenzo[b,g]thiocin, an eight-membered ring homologue of the neuroleptic agent octoclothepin
    1980, Vol. 45, Issue 2, pp. 491–503 [Abstract]
  • Evžen Kasafírek, Vladimír Felt, Ivan Krejčí and Jiří Michalský
    Synthesis of analogues of the thyreotropin releasing factor containing 2-oxoimidazolidine-1-carboxylic acid
    1980, Vol. 45, Issue 2, pp. 452–456 [Abstract]
  • Evžen Kasafírek, Ivan Krejčí and Vladimír Felt
    Synthesis of analogues of the melanocyte-stimulating hormone release-inhibiting factor containing 2-oxoimidazolidine-1-carboxylic acid
    1980, Vol. 45, Issue 1, pp. 294–297 [Abstract]
  • Karel Šindelář, Jiří Holubek, Emil Svátek, Miroslav Ryska, Jiřina Metyšová, Zdeněk Šedivý and Miroslav Protiva
    Potential metabolites of the neuroleptic agents noroxyclothepin and oxyclothepin; Synthesis of 8-chloro-3-hydroxy-10-[4-(2-hydroxyethyl)piperazino]- and -10-[4-(3-hydroxypropyl)piperazino]-10,11-dihydrodibenzo[b,f]thiepin
    1979, Vol. 44, Issue 12, pp. 3617–3626 [Abstract]
  • Zdeněk Vejdělek, Miroslav Rajšner, Emil Svátek, Jiří Holubek and Miroslav Protiva
    Synthesis of 7-chloro-5-(6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-2-methylamino-3H-1,4-benzodiazepine 4-oxide and of some related compounds
    1979, Vol. 44, Issue 12, pp. 3604–3616 [Abstract]
  • Miloš Beran, Jiří Křepelka and Miroslav Semonský
    Some 6-alkyl derivatives of D-8-ergolin-I-ylacetamide
    1979, Vol. 44, Issue 11, pp. 3385–3390 [Abstract]
  • Vladimír Valenta, Jiří Jílek, Josef Pomykáček, Antonín Dlabač, Martin Valchář, Jan Metyš and Miroslav Protiva
    Noncataleptic potential neuroleptics: 2-Methyl-10-(4-methylpiperazino)- and -10-[4-(2-hydroxyethyl)piperazino]-10,11-dihydrodibenzo[b,f]thiepin
    1979, Vol. 44, Issue 9, pp. 2677–2688 [Abstract]
  • Miroslav Rajšner, Václav Bártl, Karel Šindelář, Emil Svátek, Jiří Holubek, Jan Metyš and Miroslav Protiva
    Synthesis of new dibenzo[b,e]thiepin derivatives related to the antidepressant agent prothiadene
    1979, Vol. 44, Issue 8, pp. 2536–2549 [Abstract]
  • Jiří O. Jílek, Jiří Holubek, Emil Svátek, Miroslav Ryska, Josef Pomykáček and Miroslav Protiva
    Reaction of some 3-(phenylthioaryl)propionic acids with polyphosphoric acid; Formation of 2H-cyclopenta[k,l]thioxanthenes
    1979, Vol. 44, Issue 7, pp. 2124–2138 [Abstract]
  • Antonín Černý, Jiří Křepelka and Miroslav Semonský
    Some 6-substituted derivatives of D-8-cyanomethylergoline-I and D-8-methylergoline-I
    1979, Vol. 44, Issue 3, pp. 946–951 [Abstract]
  • Miroslav Kuchař, Václav Rejholec, Zdeněk Roubal and Oldřich Němeček
    Quantitative relationships between structure and fibrinolytic activity in the series of α-methyl-β-arylpropionic acids
    1979, Vol. 44, Issue 1, pp. 183–193 [Abstract]
  • Jiří Jílek, Jiří Holubek, Emil Svátek, Marie Bartošová, Jiřina Metyšová, Josef Pomykáček and Miroslav Protiva
    8-Chloro-3-hydroxy-10-piperazino-10,11-dihydrodibenzo[b,f]thiepins, their O-methyl derivatives and further potential metabolites of the neuroleptic agent octoclothepin
    1978, Vol. 43, Issue 11, pp. 3092–3102 [Abstract]
  • Václav Bártl, Jiří Holubek, Jiří Němec, Marie Bartošová and Miroslav Protiva
    Derivatives of 8-chloro-10,11-dihydrodibenzo[b,f]thiepin-10-amine, -10-ol and -10-thiol; Synthesis and pharmacological screening
    1978, Vol. 43, Issue 9, pp. 2427–2443 [Abstract]
  • Miroslav Rajšner, Zdeňka Kopicová, Jiří Holubek, Emil Svátek, Jan Metyš, Marie Bartošová, František Mikšík and Miroslav Protiva
    4,4-Bis(4-fluorophenyl)butylamines and their cyclic analogues; An efficient synthesis of the neuroleptic penfluridol
    1978, Vol. 43, Issue 7, pp. 1760–1777 [Abstract]
  • Viktor Zikán, Miroslav Semonský, Bohumil Kakáč, Jiří Holubek and Karel Řežábek
    Reactions of methyl esters of 3-bromo-4-(4-alkoxyphenyl)-4-oxo-2-butenoic acids with diethyl sodium malonate
    1978, Vol. 43, Issue 7, pp. 1727–1731 [Abstract]
  • Zdenko Procházka, Ivan Krejčí, Běla Kupková, Jiřina Slaninová, Vera Bojanovska, Zdeněk Prusík, Ilse A. Vosekalna, Petr Maloň, Tomislav Barth, Ivo Frič, Karel Bláha and Karel Jošt
    Synthesis and properties of the Nα-glycyl-glycyl-glycyl-8-lysine-vasopressin and its des-glycinamide derivative
    1978, Vol. 43, Issue 5, pp. 1285–1299 [Abstract]