Collect. Czech. Chem. Commun.
1990, 55, 1777-1782
https://doi.org/10.1135/cccc19901777
Partial methylation of methyl α-D- and β-D-threofuranoside
Jiří Jarýa, Miroslav Marekb and Ivan Raicha
a Laboratory of Monosaccharides, Prague Institute of Chemical Technology, 166 28 Prague 6
b Biotechnology Centre, Department of Biochemistry and Microbiology, Prague Institute of Chemical Technology, 166 28 Prague 6
Abstract
The methylation rate of hydroxyl groups of the title glycosides I and II has been studied in their reaction with methyl iodide and sodium hydroxide in acetonitrile. From the relative rate constants determined for the side and consecutive reactions taking place the differences in methylation rate of the individual hydroxyl groups have been deduced and are discussed from the standpoint of possible steric and polar effects.
