Collect. Czech. Chem. Commun. 1991, 56, 2251-2257
https://doi.org/10.1135/cccc19912251

Configurational assignment of aryl heteroaryl ketoximes by means of homonuclear NOE difference spectroscopy

Gottfried Heinisch and Wolfgang Holzer

Institute of Pharmaceutical Chemistry, University of Vienna, A-1090 Vienna, Austria

Abstract

The utility of homonuclear NOE difference spectroscopy as a simple and rapid method for the configurational assignment of aryl heteroaryl ketoximes is demonstrated employing oximes derived from 4-methoxyphenyl 2-pyrazinyl ketones, (substituted phenyl) 4-pyridazinyl ketones, and benzimidazolyl phenyl ketones.