Collect. Czech. Chem. Commun.
1991, 56, 685-694
https://doi.org/10.1135/cccc19910685
Reactions of isothiocyanates and isocyanates with some silylated nitrogen-containing nucleophiles
Jozef Gonda and Zuzana Antalová
Department of Organic Chemistry, Faculty of Natural Sciences, P. J. Šafárik University, 041 67 Košice
Abstract
Aryl isothiocyanates and arylisocyanates react with N,O-bis(trimethylsilyl)acetamide to give N-methyl-N’-arylthioureas and ureas. Also nucleophilic additions of other aprotic nucleophiles (e.g. N-trimethylsilylimidazole, N-trimethylsilylpiperidine and N-trimethylsilylmorpholine) to the N=C=X (X = O, S) group were investigated.
