Collect. Czech. Chem. Commun.
1992, 57, 216-218
https://doi.org/10.1135/cccc19920216
Preparation of Some 2,3-Dihydro-7-oxo-7H-pyrido[1,2,3-de][1,4]benzoxazine Derivatives
Stanislav Rádl, Jaroslav Moural and Radoslava Bendová
Research Institute for Pharmacy and Biochemistry, 130 60 Prague 3
Abstract
We have recently described a new reaction of 8-hydroxyquinolone II with 3-bromopropyne leading to 2,3-dihydro-3-methylene-7-oxo-7H-pyridol[1,2,3-de][1,4]benzoxazine-6-carboxylate IIIa, which could be used as an intermediate for preparation of antibacterically active compound IIIb. Now we extend the scope of the reaction.
