Collect. Czech. Chem. Commun. 1992, 57, 1111-1126
https://doi.org/10.1135/cccc19921111

The Synthesis and Identification of Isomeric Products of Enzymatic O-Demethylation of the Sympathomimetic Tetraminol - trans-3(2-Hydroxyethylamino)-5,8-dimethoxy-1,2,3,4-tetrahydro-2-naphthol

Konstantin Drandarov

Department of Biochemical Sciences, Faculty of Pharmacy, Charles University, 501 65 Hradec Králové

Abstract

The structure of the positional isomers of mono-O-demethylated metabolites (V and VI) of Tetraminol - trans-3-(2-hydroxyethylamino)-5,8-dimethoxy-1,2,3,4-tetrahydro-2-naphthol (XIX) - and the pairs of related derivatives was determined.