Collect. Czech. Chem. Commun.
1993, 58, 2729-2736
https://doi.org/10.1135/cccc19932729
Indirect Iodination of Estrogenes via Triazenes
Jiří Protivaa, Václav Křečeka, Luděk Vlka, Hana Malinováa, Eva Klinotováa, Bohumil Mácaa and Jiří Urbanb
a Department of Organic Chemistry, Charles University, 128 40 Prague 2, Czech Republic
b J. Heyrovský Institute of Physical Chemistry, Academy of Sciences of the Czech Republic, 182 23 Prague 8, Czech Republic
Abstract
Triazene derivatives of estrone and estradiol in position 2 and 4 were prepared. Their reaction with sodium iodide in an acid medium afforded the corresponding iodo derivatives. The 1H, 13C NMR and mass spectra of the compound prepared are discussed.
