Collect. Czech. Chem. Commun.
1995, 60, 594-604
https://doi.org/10.1135/cccc19950594
Michael-Michael Aldol Reaction of Chalcones with Cyanoacetylurea and Cyanoacetylpiperidine
Hani D. Tabba, Nidal M. Yousef and Mohammad M. Al-Arab
Department of Chemistry, Yarmouk University, Irbid, Jordan
Abstract
Several highly substituted cyclohexane derivatives were synthesized by the one-pot condensation of chalcones and cyanoacetylurea (2 : 1) using sodium alkoxide in anhydrous alcohol at room temperature. The structure of the reaction products was established by infrared, 1H and 13C NMR spectroscopy as well as by their elemental analysis. Single crystal X-ray crystallography shows the presence of the cyclohexane moiety.
