Collect. Czech. Chem. Commun. 1995, 60, 705-708
https://doi.org/10.1135/cccc19950705

Synthesis of Some Derivatives of 8-Aminomethyl- and 8-Azolylmethyl-2-phenyl-3H-quinazoline-4-thiones

Štefan Stankovský and Katarína Špirková

Department of Organic Chemistry, Slovak Technical University, 812 37 Bratislava, Slovak Republic

Abstract

Alkylation of cyclic amines and imides by 8-chloromethyl-2-phenyl-3H-quinazoline-4-thione, prepared by intramolecular cyclization of N-(2-chloromethylphenyl)benzimidoyl isothiocyanate, afforded ten N,N-disubstituted 8-aminomethyl-2-phenyl-3H-quinazoline-4-thiones.