Collect. Czech. Chem. Commun.
1996, 61, 147-154
https://doi.org/10.1135/cccc19960147
Fusion Reactions of N-Heterocyclic Moieties to Thiopyrano[4',3':4,5]thieno[2,3-d]pyrimidines
Essam K. Ahmeda, Johannes Fröhlichb and Fritz Sauterb
a Chemistry Department, Faculty of Science, Minia University, El-Minia, Egypt
b Institute of Organic Chemistry, Technical University Vienna, Getreidemarkt 9, A-1060 Vienna, Austria
Abstract
Derivatives of the novel heterocyclic parent systems imidazolo[1,2-a]thiopyrano[4',3':4,5]thieno[2,3-d]pyrimidine (B) and thiopyrano[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine (C) have been synthesized by fusing pyrimidine moieties to 2-amino-4,7-dihydro-5H-thieno[2,3-c]thiopyran-3-carboxylic acid ethyl ester (1) and -3-carbonitrile (10), followed by cyclization reactions of the title intermediates A thus obtained.
Keywords: Annelation reactions; Thiopyrano[4',3':4,5]thieno[2,3-d]pyrimidines.