Synthesis and Antibacterial Properties of Some 4-Amino Substituted 2-Phenyl-6<i>H</i>-5,1,3-benzothiadiazocines

Bodajla, Michal; Stankovský, Štefan; Špirková, Katarína; Jantová, Soňa

doi:10.1135/cccc19961681

CCCC > Archive > 1996, Volume 61 > Issue 11 > p. 1681

Synthesis and Antibacterial Properties of Some 4-Amino Substituted 2-Phenyl-6H-5,1,3-benzothiadiazocines

Michal Bodajla^a, Štefan Stankovský^a, Katarína Špirková^a and Soňa Jantová^b

^a Department of Organic Chemistry, Slovak Technical University, 812 37 Bratislava, Slovak Republic
^b Department of Microbiology, Biochemistry and Biology, Slovak Technical University, 812 37 Bratislava, Slovak Republic

Abstract

Some 4-amino substituted 2-phenyl-6H-5,1,3-benzothiadiazocines (4a-4j) were prepared by cyclization of the corresponding N¹-[N-(2-chloromethylphenyl)benzimidoyl]-N²-substituted thioureas (3a-3j). The IR,¹H NMR and mass spectra of the title compounds are reported together with the results of antibacterial screening.

Keywords: N-(2-Chloromethylphenyl)benzimidoyl isothiocyanate; 6H-5,1,3-benzothiadiazocines.

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Synthesis and Antibacterial Properties of Some 4-Amino Substituted 2-Phenyl-6H-5,1,3-benzothiadiazocines

Abstract