Collect. Czech. Chem. Commun. 1996, 61, S81-S84
https://doi.org/10.1135/cccc1996s081

A simple synthetic route to the preparation of 2-(1-phosphonoalkoxy)ethyl derivatives of heterocyclic bases as novel nucleotide analogs related to PMEA

Ivan Rosenberg and Šárka Králíková

Individual author index pages


Other CCCC articles of these authors

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  • Dominik Rejman and Ivan Rosenberg
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  • Šárka Králíková, Miloš Buděšínský, Ivana Kavenová and Ivan Rosenberg
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    Symposium Series 2002, Vol. 5, pp. 356–357 [Abstract]
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  • Zdeněk Točík, Radek Liboska, Ivan Barvík, Jr., Miloš Buděšínský, Milena Masojídková, Ivana Kavenová and Ivan Rosenberg
    Isosteric phosphonate mono- and oligonucleotides originating from 4',5'-didehydronucleoside precursors: Some synthetic possibilities and limitations
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    From nucleoside phosphonic acids to modified oligonucleotides
    Symposium Series 2002, Vol. 5, pp. 200–207 [Abstract]
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    Symposium Series 2005, Vol. 7, pp. 453–454 [Abstract]
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  • Radek Pohl, Dominik Rejman, Petr Kočalka and Ivan Rosenberg
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  • Dominik Rejman, Petr Kočalka, Radek Pohl and Ivan Rosenberg
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    Symposium Series 2011, Vol. 12, pp. 430–432 [Abstract]
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  • Ondřej Šimák, Petr Pachl, Tomáš Jandušík, Jiří Brynda, Miloš Buděšínský and Ivan Rosenberg
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  • Michal Šála, Milan Dejmek, Eliška Procházková, Hubert Hřebabecký, Jiří Rybáček, Martin Dračínský, Pavel Novák, Šárka Rosenbergová, Jiří Fukal, Vladimír Sychrovský, Ivan Rosenberg and Radim Nencka
    Novel conformationally locked nucleosides and oligonucleotides based on bicyclo[3.2.1]octane scaffold as a pseudosugar moiety
    Symposium Series 2014, Vol. 14, pp. 379–380 [Abstract]
    Published online 2015-07-06 23:09:07
  • Magdalena Petrová, Miloš Buděšínský, Eva Zborníková, Natalia Panova, Pavel Novák and Ivan Rosenberg
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    Symposium Series 2014, Vol. 14, pp. 348–349 [Abstract]
    Published online 2015-07-06 23:07:50
  • Ondřej Páv, Eva Zborníková, Miloš Buděšínský and Ivan Rosenberg
    Phosphanucleosides containing 1-hydroxymethylphospholane 1-oxide ring
    Symposium Series 2014, Vol. 14, pp. 344–345 [Abstract]
    Published online 2015-07-06 23:07:39
  • Ondřej Kostov, Eva Zborníková, Miloš Buděšínský, Pavel Novák and Ivan Rosenberg
    Sulfur-containing phosphonate monomers for oligonucleotide synthesis
    Symposium Series 2014, Vol. 14, pp. 308–309 [Abstract]
    Published online 2015-07-06 23:06:12
  • Martin Maxmilian Kaiser, Pavel Novák, Šárka Rosenbergová, Lenka Poštová-Slavětínská, Ivan Rosenberg and Zlatko Janeba
    Oligonucleotides modified with acyclic nucleoside phosphonate (HPEP) units
    Symposium Series 2014, Vol. 14, pp. 293–294 [Abstract]
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  • Ivana Poláková, Miloš Buděšínský, Zdeněk Točík and Ivan Rosenberg*
    Tetrofuranose nucleoside phosphonic acids: Synthesis and properties
    2011, Vol. 76, Issue 5, pp. 503–536 [Abstract]
  • Dominik Rejman*, Petr Kočalka, Radek Pohl, Zdeněk Točík and Ivan Rosenberg*
    Synthesis and hybridization of oligonucleotides modified at AMP sites with adenine pyrrolidine phosphonate nucleotides
    2009, Vol. 74, Issue 6, pp. 935–955 [Abstract]
  • Ondřej Pačes, Zdeněk Točík* and Ivan Rosenberg*
    A New Linker for Solid-Phase Synthesis of Oligonucleotides with Terminal Phosphate Group
    2008, Vol. 73, Issue 1, pp. 32–43 [Abstract]
  • Tuomas Lönnberg, Šárka Králíková, Ivan Rosenberg and Harri Lönnberg*
    Kinetics and Mechanisms for the Isomerization of Internucleosidic 3'-O-P-CH2-5' and 3'-O-P-CH(OH)-5' Linkages to Their 2',5'-Counterparts
    2006, Vol. 71, Issue 6, pp. 859–870 [Abstract]
  • Dominik Rejman, Šárka Králíková, Zdeněk Točík, Radek Liboska and Ivan Rosenberg*
    Selective Cleavage of O-(Dimethoxytrityl) Protecting Group with Sodium Periodate
    2002, Vol. 67, Issue 4, pp. 502–508 [Abstract]
  • Jaroslav Zajíček, Ivan Rosenberg, Radek Liboska, Zdeněk Točík, G. Victor Fazakerley, Wilhelm Guschlbauer and Antonín Holý
    Conformational Studies on Diribonucleoside Monophosphate Analogs Containing a Nonisosteric, Isopolar, Phosphonate-Based Internucleotide Linkage
    1997, Vol. 62, Issue 1, pp. 83–98 [Abstract]
  • Magdalena Endová, Milena Masojídková and Ivan Rosenberg
    Synthesis of some derivatives of 1-[2-deoxy-3,5-O-(1-diethylphosphono)alkylidene-β-D-threo-pentofuranosyl]thymine substituted in the ω-position of the alkylidene moiety
    1996, Vol. 61, Special Issue, pp. S167–S170 [Abstract]
  • Ivan Rosenberg and Radek Liboska
    A novel class of PME and HPMP derivatives of nucleobases modified in the heterocyclic moiety
    1996, Vol. 61, Special Issue, pp. S126–S128 [Abstract]
  • Šárka Králíková and Ivan Rosenberg
    The addition of phosphorous acid esters on the carbonyl group of 3'-ketonucleosides and nucleoside-5'-aldehydes: Synthesis of novel class of nucleotide analogs
    1996, Vol. 61, Special Issue, pp. S124–S125 [Abstract]
  • Dominik Rejman and Ivan Rosenberg
    Synthesis of 2'-alkoxy and 2'-aryloxy derivatives of 9-(2-phosphonomethoxyethyl)adenine (PMEA) and related compounds
    1996, Vol. 61, Special Issue, pp. S122–S123 [Abstract]
  • Zdeněk Točík, Iva Kavenová and Ivan Rosenberg
    Preparation of 4'-phosphonomethoxy derivatives of nucleosides: Addition of hydroxymethanephosphonic acid dialkyl esters to 4',5'-didehydronucleosides
    1996, Vol. 61, Special Issue, pp. S76–S80 [Abstract]
  • Radek Liboska, Milena Masojídková and Ivan Rosenberg
    Carbocyclic Phosphonate-Based Nucleotide Analogs Related to PMEA II. Racemic cis-Configured Derivatives
    1996, Vol. 61, Issue 5, pp. 778–790 [Abstract]
  • Radek Liboska, Milena Masojídková and Ivan Rosenberg
    Carbocyclic Phosphonate-Based Nucleotide Analogs Related to PMEA. I. Racemic trans-Configured Derivatives
    1996, Vol. 61, Issue 2, pp. 313–332 [Abstract]
  • Hana Dvořáková, Antonín Holý and Ivan Rosenberg
    Synthesis of Some 2'-C-Alkyl Derivatives of 9-(2-Phosphonomethoxyethyl)adenine and Related Compounds
    1994, Vol. 59, Issue 9, pp. 2069–2094 [Abstract]
  • Radek Liboska and Ivan Rosenberg
    Synthesis and antiviral activity of novel carbocyclic nucleoside and nucleotide analogs
    1993, Vol. 58, Special Issue, pp. S259–S261 [Abstract]
  • Miroslav Otmar, Ivan Rosenberg, Milena Masojídková and Antonín Holý
    [5-(9-Adeninyl)-5'-deoxy-L-pentofuranosyl]phosphonates: Conformationally restricted nucleotide analogs related to (S)-HPMPA
    1993, Vol. 58, Special Issue, pp. S256–S258 [Abstract]
  • Ivan Rosenberg and Radek Liboska
    Preparation of isosters of 9-[2-(phosphonomethoxy)ethyl] adenine
    1993, Vol. 58, Special Issue, pp. S94–S97 [Abstract]
  • Antonín Holý, Hana Dvořáková and Ivan Rosenberg
    Synthesis and antiviral activity of some 2'-C-alkyl derivatives of 9-(2-phosphonomethoxyethyl)adenine
    1993, Vol. 58, Special Issue, pp. S86–S90 [Abstract]
  • Miroslav Otmar, Ivan Rosenberg, Milena Masojídková and Antonín Holý
    [5-(Adenin-9-yl)-5-deoxy-L-pentofuranosyl]phosphonates - A Novel Type of Nucleotide Analogs Related to HPMPA. II. Synthesis of L-ribo and L-xylo Configurated Derivatives by Recyclization of Diethyl (5-RS)-[1,2-O-Isopropylidene-5-O-methanesulfonyl-D-pentofuranos-5-C-yl]phosphonates under Acidic Conditions
    1993, Vol. 58, Issue 9, pp. 2180–2196 [Abstract]
  • Miroslav Otmar, Ivan Rosenberg, Milena Masojídková and Antonín Holý
    [5-(Adenin-9-yl)-5-deoxypentofuranosyl]phosphonates - A Novel Type of Nucleotide Analogs Related to HPMPA. I. Derivatives with L-arabino, D-arabino, 2-Deoxy-L-erythro and 2-Deoxy-L-threo Configuration
    1993, Vol. 58, Issue 9, pp. 2159–2179 [Abstract]
  • Jiří Smrt, Luboš Arnold, Jan Svoboda, Roman Hák and Ivan Rosenberg
    Synthesis of Oligodeoxynucleotides Eliminating the Use of Acetonitrile
    1993, Vol. 58, Issue 7, pp. 1692–1698 [Abstract]
  • Tomas Cihlar, Ivan Votruba, Květoslava Horská, Radek Liboska, Ivan Rosenberg and Antonín Holý
    Metabolism of 1-(S)-(3-Hydroxy-2-phosphonomethoxypropyl)cytosine (HPMPC) in Human Embryonic Lung Cells
    1992, Vol. 57, Issue 3, pp. 661–672 [Abstract]
  • Katarina Šedivá, Ivan Votruba, Antonín Holý and Ivan Rosenberg
    Purine nucleoside phosphorylase: Isolation and characterization
    1990, Vol. 55, Issue 12, pp. 2987–2999 [Abstract]
  • Květa Horská, Aleš Cvekl, Ivan Rosenberg, Antonín Holý and Karel Šebesta
    DNA-dependent RNA polymerase mediated formation of methylphosphonyl internucleotide linkage
    1990, Vol. 55, Issue 8, pp. 2100–2109 [Abstract]
  • Antonín Holý, Ivan Rosenberg and Hana Dvořáková
    Synthesis of N-(2-(2-phosphonylethoxy)ethyl) derivatives of heterocyclic bases
    1990, Vol. 55, Issue 3, pp. 809–818 [Abstract]
  • Antonín Holý, Ivan Rosenberg and Hana Dvořáková
    Synthesis of (3-hydroxy-2-phosphonylmethoxypropyl) derivatives of heterocyclic bases
    1989, Vol. 54, Issue 9, pp. 2470–2501 [Abstract]
  • Antonín Holý, Ivan Rosenberg and Hana Dvořáková
    Synthesis of N-(2-phosphonylmethoxyethyl) derivatives of heterocyclic bases
    1989, Vol. 54, Issue 8, pp. 2190–2210 [Abstract]
  • Aleš Cvekl, Květa Horská, Karel Šebesta, Ivan Rosenberg and Antonín Holý
    Trinucleotide AUA and UAU formation catalyzed by wheat germ RNA polymerase II
    1989, Vol. 54, Issue 3, pp. 811–818 [Abstract]
  • Ivan Rosenberg, Antonín Holý and Milena Masojídková
    Phosphonylmethoxyalkyl and phosphonylalkyl derivatives of adenine
    1988, Vol. 53, Issue 11, pp. 2753–2777 [Abstract]
  • Antonín Holý, Masahiko Nishizawa, Ivan Rosenberg and Ivan Votruba
    The effect of phosphonylmethyl analogs of ribonucleoside 5'-diphosphates on (E. coli) polynucleotide phosphorylase catalyzed reactions
    1987, Vol. 52, Issue 12, pp. 3042–3057 [Abstract]
  • Antonín Holý and Ivan Rosenberg
    Synthesis of 9-(2-phosphonylmethoxyethyl)adenine and related compounds
    1987, Vol. 52, Issue 11, pp. 2801–2809 [Abstract]
  • Ivan Rosenberg and Antonín Holý
    Synthesis of potential prodrugs and metabolites of 9-(S)-(3-hydroxy-2-phosphonylmethoxypropyl)adenine
    1987, Vol. 52, Issue 11, pp. 2792–2800 [Abstract]
  • Antonín Holý and Ivan Rosenberg
    Synthesis of isomeric and enantiomeric O-phosphonylmethyl derivatives of 9-(2,3-dihydroxypropyl)adenine
    1987, Vol. 52, Issue 11, pp. 2775–2791 [Abstract]
  • Ivan Rosenberg and Antonín Holý
    Synthesis of phosphonylmethyl analogues of diribonucleoside monophosphates containing modified internucleotide bond
    1987, Vol. 52, Issue 10, pp. 2572–2588 [Abstract]
  • Milena Masojídková, Jaroslav Zajíček, Miloš Buděšínský, Ivan Rosenberg and Antonín Holý
    Conformational study on ribonucleoside O-phosphonylmethyl derivatives by 1H NMR spectroscopy
    1985, Vol. 50, Issue 8, pp. 1899–1905 [Abstract]
  • Antonín Holý and Ivan Rosenberg
    An improved synthesis of S-adenosyl-L-homocysteine and related compounds
    1985, Vol. 50, Issue 7, pp. 1514–1518 [Abstract]
  • Ivan Rosenberg and Antonín Holý
    Phosphonylmethyl analogues of ribonucleoside 2',3'-cyclic phosphates and 2'(3')-nucleotide methyl esters: Synthesis and properties
    1985, Vol. 50, Issue 7, pp. 1507–1513 [Abstract]
  • Ivan Votruba, Antonín Holý and Ivan Rosenberg
    Affinity chromatography of rat liver S-adenosyl-L-homocysteine hydrolase
    1983, Vol. 48, Issue 9, pp. 2549–2557 [Abstract]
  • Jiří Veselý, Ivan Rosenberg and Antonín Holý
    Donor activity of 5'-O-phosphonylmethyl analogues of ATP and GTP in the phosphorylation of uridine catalyzed by uridine kinase from mouse leukemic cells
    1983, Vol. 48, Issue 6, pp. 1783–1787 [Abstract]
  • Květa Horská, Ivan Rosenberg, Antonín Holý and Karel Šebesta
    5'-O-diphosphorylphosphonylmethylribonucleosides - A new group of DNA-dependent RNA polymerase inhibitors
    1983, Vol. 48, Issue 5, pp. 1352–1357 [Abstract]
  • Ivan Rosenberg and Antonín Holý
    Preparation of 2'(3')-O-phosphonylmethyl derivatives of ribonucleosides
    1983, Vol. 48, Issue 3, pp. 778–789 [Abstract]
  • Jiří Veselý, Ivan Rosenberg and Antonín Holý
    Inhibition by CTP and UTP analogues of uridine kinase from mouse leukemic cells
    1982, Vol. 47, Issue 12, pp. 3464–3469 [Abstract]
  • Antonín Holý and Ivan Rosenberg
    Preparation of 5'-O-phosphonylmethyl analogues of nucleoside-5'-phosphates, 5'-diphosphates and 5'-triphosphates
    1982, Vol. 47, Issue 12, pp. 3447–3463 [Abstract]
  • Pavol Kois, Ivan Rosenberg and Antonín Holý
    Affinity chromatography of guanyloribonuclease from streptomyces aureofaciens
    1980, Vol. 45, Issue 10, pp. 2839–2846 [Abstract]
  • Ivan Rosenberg and Antonín Holý
    Nucleolytic enzymes of rape seedlings II. Unspecific acid phosphomonoester hydrolase
    1979, Vol. 44, Issue 11, pp. 3327–3340 [Abstract]
  • Antonín Holý and Ivan Rosenberg
    New pyrimidine (uridine) specific cyclizing 2'-ribonucleotidyltransferase and nonspecific decyclizing 2',3'-phosphodiesterase
    1979, Vol. 44, Issue 3, pp. 957–975 [Abstract]