Collect. Czech. Chem. Commun. 1997, 62, 124-129
https://doi.org/10.1135/cccc19970124

Synthesis of New 2-Hydrazono-4-oxo-5-thiazolidineacetic Acids and Their Alkylamides

Ivica Sigmundová and Mária Mečiarová

Department of Organic Chemistry, Comenius University, 842 15 Bratislava, Slovak Republic

Abstract

The direct two step synthesis of three new 2-hydrazono-4-oxo-5-thiazolidineacetic acids from thiosemicarbazide, the appropriate ketones (acetophenone, cyclopentanone, cyclohexanone) and maleic anhydride is described. The prepared acids were transformed, via their mixed anhydrides with ethyl carbonate, into their alkylamides in a one-pot procedure.

Keywords: 2-Hydrazono-4-oxo-5-thiazolidine; Effect on chlorophyll production.