Collect. Czech. Chem. Commun. 1997, 62, 1503-1510
https://doi.org/10.1135/cccc19971503

Combination of the Topliss Approach with the Free-Wilson Analysis in the Study of Antimycobacterial Activityof 4-Alkylthiobenzanilides

Jiří Kuneša, Jiří Jáchyma, Petr Jiráskoa, Želmíra Odlerováb and Karel Waissera

a Department of Inorganic and Organic Chemistry, Faculty of Pharmacy, Charles University, 500 05 Hradec Králové, Czech Republic
b Institute of Preventive and Clinical Medicine, 833 01 Bratislava, Slovak Republic

Individual author index pages


Other CCCC articles of these authors

  • Vojtěch Balšánek, Lucie Tichotová, Jiří Kuneš, Marcel Špulák, Milan Pour*, Ivan Votruba and Vladimír Buchta
    Cytostatic tetrazole–butenolide conjugates: linking tetrazole and butenolide rings via stille coupling and biological activity of the target substances
    2009, Vol. 74, Issue 7-8, pp. 1161–1178 [Abstract]
  • Marta Kučerová-Chlupáčová, Veronika Opletalová*, Josef Jampílek, Jan Doležel, Jiří Dohnal, Milan Pour, Jiří Kuneš and Viktor Voříšek
    New Hydrophobicity Constants of Substituents in Pyrazine Rings Derived from RP-HPLC Study
    2008, Vol. 73, Issue 1, pp. 1–18 [Abstract]
  • Ivan Šnajdr, Jan Pavlík, Radan Schiller, Jiří Kuneš and Milan Pour*
    Pentenolide Analogues of Antifungal Butenolides: Strategies Towards 3,6-Disubstituted Pyranones and Unexpected Loss of Biological Effect
    2007, Vol. 72, Issue 11, pp. 1472–1498 [Abstract]
  • Veronika Opletalová*, Milan Pour, Jiří Kuneš, Vladimír Buchta, Luís Silva, Katarína Kráľová, Marta Chlupáčová, Dana Meltrová, Milan Peterka and Martina Posledníková
    Synthesis and Biological Evaluation of (E)-3-(Nitrophenyl)-1-(pyrazin-2-yl)prop-2-en-1-ones
    2006, Vol. 71, Issue 1, pp. 44–58 [Abstract]
  • Karel Waisser*, Milan Peřina, Věra Klimešová and Jarmila Kaustová
    On the Relationship between the Structure and Antimycobacterial Activity of Substituted N-Benzylsalicylamides
    2003, Vol. 68, Issue 7, pp. 1275–1294 [Abstract]
  • Jiří Kuneš, Vojtěch Balšánek, Milan Pour* and Vladimír Buchta
    Synthesis and Antifungal Activity Evaluation of 3-Hetaryl-2,5-dihydrofuran-2-ones. An Unusual Fragmentation of the Oxazole Ring via 2,3-Selenoxide Shift
    2001, Vol. 66, Issue 12, pp. 1809–1830 [Abstract]
  • Karel Waisser*, Miloš Macháček, Hynek Dostál, Jiří Gregor, Lenka Kubicová, Věra Klimešová, Jiří Kuneš, Karel Palát, Jr., Jana Hladůvková, Jarmila Kaustová and Ute Möllmann
    Relationships Between the Chemical Structure of Substances and Their Antimycobacterial Activity Against Atypical Strains. Part 18. 3-Phenyl-2H-1,3-benzoxazine-2,4(3H)-diones and Isosteric 3-Phenylquinazoline-2,4(1H,3H)-diones
    1999, Vol. 64, Issue 11, pp. 1902–1924 [Abstract]
  • Miroslav Holík*, Zdeněk Friedl, Karel Waisser and Jiří Gregor
    Multivariate Regression with Substituent Shift Increments. IV. 2-(4-X-Phenyl)-1,3-dihydro-2H-isoindole-1,3-diones and 3-(4-X-Phenyl)-3,4-dihydro-2H-1,3-benzoxazine-2,4-diones
    1999, Vol. 64, Issue 10, pp. 1709–1726 [Abstract]
  • Karel Waisser*, Karel Palát, Jr. and Otto Exner*
    Substituent Effects on Conformational Equilibria: Substituted Thiobenzanilides
    1999, Vol. 64, Issue 8, pp. 1295–1306 [Abstract]
  • Věra Klimešová*, Martin Svoboda, Karel Waisser, Milan Pour and Jarmila Kaustová
    Synthesis and Antimicrobial Activity of New 4-(Benzylsulfanyl)pyridine Derivatives
    1999, Vol. 64, Issue 2, pp. 417–434 [Abstract]
  • Václav Kozmík, Pavel Lhoták, Želmíra Odlerová and Jaroslav Paleček
    Azachalcone Derivatives and Their Bis Substituted Analogs as Novel Antimycobacterial Agents
    1998, Vol. 63, Issue 5, pp. 698–712 [Abstract]
  • Katarína Kráľová, František Šeršeň, Věra Klimešová and Karel Waisser
    Effect of 2-Alkylthio-4-pyridinecarbothiamides on Photosynthetic Electron Transport in Spinach Chloroplasts
    1997, Vol. 62, Issue 3, pp. 516–520 [Abstract]
  • Hans-Dietrich Stachel, Želmíra Odlerová and Karel Waisser
    A New Pharmacophore of Potential Antimycobacterial Activity: The Disulfide Group in the Ring of Alicyclic Compounds
    1997, Vol. 62, Issue 3, pp. 510–515 [Abstract]
  • Jiří Hartl, Martin Doležal, Jana Krinková, Antonín Lyčka and Želmíra Odlerová
    Synthesis and Antituberculotic Activity of 5-Alkyl-6-chloro-2-pyrazinecarboxamides and Corresponding Thioamides
    1996, Vol. 61, Issue 7, pp. 1109–1114 [Abstract]
  • Martin Doležal, Jiří Hartl, Antonín Lyčka, Vladimír Buchta and Želmíra Odlerová
    Synthesis and Antituberculotic Properties of Some Substituted Pyrazinecarbothioamides
    1996, Vol. 61, Issue 7, pp. 1102–1108 [Abstract]
  • Karel Waisser, Jiří Kuneš, Alexandr Hrabálek, Miloš Macháček and Želmíra Odlerová
    New Groups of Potential Antituberculotics: 5-Alkylthio-1-aryltetrazoles
    1996, Vol. 61, Issue 5, pp. 791–798 [Abstract]
  • Martin Doležal, Jiří Hartl, Antonín Lyčka, Vladimír Buchta and Želmíra Odlerová
    Synthesis and Antituberculotic Activity of Some Substituted 3-Arylamino-5-cyano-2-pyrazinecarboxamides
    1995, Vol. 60, Issue 7, pp. 1236–1241 [Abstract]
  • Karel Waisser, Jiří Kuneš, Alexandr Hrabálek and Želmíra Odlerová
    New Groups of Potential Antituberculotics: Bis(1-aryltetrazol-5-yl) Disulfides. Structure Activity Relationship
    1994, Vol. 59, Issue 1, pp. 234–238 [Abstract]
  • Karel Waisser, Lenka Kubicová, Věra Klimešová and Želmíra Odlerová
    New Groups of Potential Antituberculotics: 3-Aryl-2H,4H-benz[e][1,3]oxazine-2,4-diones. Comparison of the Topliss Approach with Regression Analysis
    1993, Vol. 58, Issue 12, pp. 2977–2982 [Abstract]
  • Karel Waisser, Lenka Kubicová and Želmíra Odlerová
    Antituberculotic 4'-Cyclohexylthiobenzanilides: Combination of Free-Wilson Method in QSAR with Topliss Approach
    1993, Vol. 58, Issue 1, pp. 205–212 [Abstract]
  • Karel Waisser, Miloš Macháček, Želmíra Odlerová, Wilfried Thiel and Roland Mayer
    Antimycobacterial 2-Arylamino-2-Thioxoacetamides
    1993, Vol. 58, Issue 1, pp. 197–204 [Abstract]
  • Karel Waisser, Jiří Kuneš, Jiří Klimeš, Miroslav Polášek and Želmíra Odlerová
    Relations between Structure and Antituberculotic Activity of 4-Alkoxybenzoic Acids
    1993, Vol. 58, Issue 1, pp. 191–196 [Abstract]
  • Karel Waisser, Jiří Kuneš and Želmíra Odlerová
    Correlation of structural parameters with antituberculotic activity in a group of 2-benzamidobenzothiazoles
    1991, Vol. 56, Issue 12, pp. 2978–2985 [Abstract]
  • Miroslav Polášek, Karel Waisser and Tomáš Bouček
    Determination of the substituent constant σp- for the thioamide group -CSNH2 from the ionization of anilines and phenols
    1991, Vol. 56, Issue 12, pp. 2964–2968 [Abstract]
  • Karel Waisser and Jana Bořková
    Relations between structure and antituberculotic activity in a group of 10-piperazino-10,11-dihydrodibenzo[b,f]thiepins
    1991, Vol. 56, Issue 11, pp. 2395–2401 [Abstract]
  • Karel Waisser, Jiří Vanžura, Alexandr Hrabálek, Jarmila Vinšová, Štefan Grešák, Jiří Hruška and Želimíra Odlerová
    Antimycobacterial derivatives of tetrazole
    1991, Vol. 56, Issue 11, pp. 2389–2394 [Abstract]
  • Karel Dlabal, Karel Palát, Antonín Lyčka and Želmíra Odlerová
    Synthesis and 1H and 13C NMR spectra of sulfur derivatives of pyrazine derived from amidation product of 2-chloropyrazine and 6-chloro-2-pyrazinecarbonitrile. Tuberculostatic activity
    1990, Vol. 55, Issue 10, pp. 2493–2501 [Abstract]
  • Karel Waisser, Nestor Houngbedji, Miloš Macháček, Miroslav Sekera, Josef Urban and Želmíra Odlerová
    Antimycobacterial thiobenzanilides
    1990, Vol. 55, Issue 1, pp. 307–316 [Abstract]
  • Naďa Zimová, Ivan Němec, Miroslava Ehlová and Karel Waisser
    The effect of the structure of the substituent in position ten on the voltammetric behaviour of phenothiazin derivatives
    1990, Vol. 55, Issue 1, pp. 63–71 [Abstract]
  • Karel Waisser, Miloš Macháček, Jean Lebvoua, Jiří Hrbata and Jaroslav Dršata
    Quantitative relations between chemical structure and hepatotoxicity of thiobenzamides
    1988, Vol. 53, Issue 11, pp. 2957–2961 [Abstract]
  • Otto Exner and Karel Waisser
    Dipole moment and electron distribution of the thioamide group
    1982, Vol. 47, Issue 3, pp. 828–837 [Abstract]