Collect. Czech. Chem. Commun.
1999, 64, 288-298
https://doi.org/10.1135/cccc19990288
Synthesis of New Potential Bis-Intercalators Based on Chiral Pyridine-2,6-dicarboxamides
Abd El-Galil Amra, Osama I. Abd El-Salama, Abd El-Hamid Attiaa and Ivan Stiborb,*
a Department of Organic Chemistry, National Research Centre, Dokki, Cairo-12622, Egypt
b Department of Organic Chemistry, Prague Institute of Chemical Technology, 166 28 Prague 6, Czech Republic
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- Yilmaz Mehmet, Inal Aslı Ustalar: Microwave assisted synthesis of 2,3-dihydro-4H-benzo[4,5]thiazolo[3,2-a]furo[2,3-d] pyrimidin-4-ones by radical addition of 2-hydroxy-4H-benzo[4,5]thiazolo[3,2-a] pyrimidin-4-ones to various conjugated alkenes and dienes mediated Mn(OAc)3. Tetrahedron 2022, 116, 132806. <https://doi.org/10.1016/j.tet.2022.132806>
- Amr A. E., Elsayed E. A., Al-Sayady A. I.: Synthesis and Antimicrobial Activity of Novel N3,N5-Bis[1-({1-[2-((E)-benzylidene)hydrazinyl]-1-oxo-3-phenylpropan-2-yl}amino)-3-methyl-1-oxobutan-2-yl]pyridine-3,5-dicarboxamides. Russ J Gen Chem 2021, 91, 1099. <https://doi.org/10.1134/S1070363221060177>
- Abo-Ghalia Mohamed H., Moustafa Gaber O., Amr Abd El-Galil E., Naglah Ahmed M., Elsayed Elsayed A., Bakheit Ahmed H.: Anticancer Activities of Newly Synthesized Chiral Macrocyclic Heptapeptide Candidates. Molecules 2020, 25, 1253. <https://doi.org/10.3390/molecules25051253>
- Smolyar Ivan V., Yudin Andrei K., Nenajdenko Valentine G.: Heteroaryl Rings in Peptide Macrocycles. Chem. Rev. 2019, 119, 10032. <https://doi.org/10.1021/acs.chemrev.8b00789>
- Amr Abd El-Galil E., Abo-Ghalia Mohamed H., Moustafa Gaber O., Al-Omar Mohamed A., Nossier Eman S., Elsayed Elsayed A.: Design, Synthesis and Docking Studies of Novel Macrocyclic Pentapeptides as Anticancer Multi-Targeted Kinase Inhibitors. Molecules 2018, 23, 2416. <https://doi.org/10.3390/molecules23102416>
- Abdel Salam Osama I., Khalifa Nagy M., Said Said A., Amr Abd El-Galil E.: Synthesis and antimicrobial activities of some newly 2,4,6-tri-substituted pyridine derivatives. Res Chem Intermed 2014, 40, 1147. <https://doi.org/10.1007/s11164-013-1028-0>
- Khayyat Suzan, Amr Abd: Synthesis and Biological Activities of Some New (Nα-Dinicotinoyl)- bis-L-Leucyl Linear and Macrocyclic Peptides. Molecules 2014, 19, 10698. <https://doi.org/10.3390/molecules190810698>
- Assy Mohamed G., Sherif Mohamed H., Amr Abd El-Galil E., Abdelsalam Osama I., Al-Omar Mohamed A., Abdalla Mohamed M., Ragab Islam: Synthesis and Reactions of Some Heterocyclic Candidates Based on 2-Amino-4,5,6,7-tetrahydrobenzo[b]thiophene Moiety as Anti-Arrhythmic Agents. J. Heterocyclic Chem. 2013, 50, 766. <https://doi.org/10.1002/jhet.1554>
- Louhichi Nesrine, Houas Amel, Hamadi Naoufel Ben, Msaddek Moncef: Synthesis and chemistry of new spiro‐Δ1‐pyrazoline. Journal of Heterocyclic Chem 2012, 49, 267. <https://doi.org/10.1002/jhet.827>
- Al-Mohizea Abdullah M., Al-Omar Mohamed A., Abdalla Mohamed M., Amr Abdel-Galil E.: 5α-Reductase inhibitors, antiviral and anti-tumor activities of some steroidal cyanopyridinone derivatives. International Journal of Biological Macromolecules 2012, 50, 171. <https://doi.org/10.1016/j.ijbiomac.2011.10.017>
- Abdalla Mohamed M., Al-Omar Mohamed A., Bhat Mashooq A., Amr Abdel-Galil E., Al-Mohizea Abdullah M.: Steroidal pyrazolines evaluated as aromatase and quinone reductase-2 inhibitors for chemoprevention of cancer. International Journal of Biological Macromolecules 2012, 50, 1127. <https://doi.org/10.1016/j.ijbiomac.2012.02.006>
- Abdalla Mohamed M., Al-Omar Mohamed A., Al-Salahi Rashad A., Amr Abdel-Galil E., Sabrye Nermien M.: A new investigation for some steroidal derivatives as anti-Alzheimer agents. International Journal of Biological Macromolecules 2012, 51, 56. <https://doi.org/10.1016/j.ijbiomac.2012.04.012>
- El-Salam Osama, Al-Omar Mohamed, Fayed Ahmed, Flefel Eman, Amr Abd: Synthesis of New Macrocyclic Polyamides as Antimicrobial Agent Candidates. Molecules 2012, 17, 14510. <https://doi.org/10.3390/molecules171214510>
- Abounassif M. A., Al‐Omar M. A., Amr A.‐G. E., Mostafa G. A. E.: PVC membrane sensor for potentiometric determination of iron (II) in some pharmaceutical formulations based on a new neutral ionophore. Drug Testing and Analysis 2011, 3, 373. <https://doi.org/10.1002/dta.231>
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- Al‐Omar Mohamed A., Amr Abd El‐Galil E., Al‐Salahi Rashad A.: Anti‐inflammatory, Analgesic, Anticonvulsant and Antiparkinsonian Activities of Some Pyridine Derivatives Using 2,6‐Disubstituted Isonicotinic Acid Hydrazides. Archiv der Pharmazie 2010, 343, 648. <https://doi.org/10.1002/ardp.201000088>
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- Al-Salahi Rashad A., Al-Omar Mohamed A, Amr Abd El-Galil E: Synthesis of Chiral Macrocyclic or Linear Pyridine Carboxamides from Pyridine-2,6-dicarbonyl Dichloride as Antimicrobial Agents. Molecules 2010, 15, 6588. <https://doi.org/10.3390/molecules15096588>
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- Yin Shaohong, Cui Yu, Xia Guangming, Zhang Yanju, Sun Guoxin: (−)-Dimethyl 3,3′-diphenyl-2,2′-[pyridine-2,6-diylbis(carbonylimino)]dipropanoate. Acta Crystallogr E Struct Rep Online 2009, 65, o1713. <https://doi.org/10.1107/S1600536809023721>
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- Abdulla Mohamed M.: Anti-inflammatory activity of heterocyclic systems using abietic acid as starting material. Monatsh Chem 2008, 139, 697. <https://doi.org/10.1007/s00706-007-0804-1>
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- Abd El-Latif Nehad, Abdulla Mohamed, Amr Abd: New steroidal derivatives synthesized using 3β-hydroxyandrosten-17-one as starting material. Acta Pharmaceutica 2008, 58, 43. <https://doi.org/10.2478/v10007-007-0044-2>
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- Amr Abd El-Galil E., Sabry Nermien M., Abdulla Mohamed M.: Synthesis, Reactions, and Anti-inflammatory Activity of Heterocyclic Systems Fused to a Thiophene Moiety Using Citrazinic Acid As Synthon. Monatsh. Chem. 2007, 138, 699. <https://doi.org/10.1007/s00706-007-0651-0>
- Jansa Petr, Macháček Vladimír, Nachtigall Petr, Wsól Vladimír, Svobodová Markéta: Coordination Compounds Based on 1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic Acid. Molecules 2007, 12, 1064. <https://doi.org/10.3390/12051064>
- Amr Abdel‐Galil E., Abdulla Mohamed M.: Synthesis and Anti‐inflammatory Activities of New Cyanopyrane Derivatives Fused with Steroidal Nuclei. Archiv der Pharmazie 2006, 339, 88. <https://doi.org/10.1002/ardp.200500209>
- Amr Abd El-Galil E., Abdel-Latif Nehad A., Abdalla Mohamed M.: Synthesis and antiandrogenic activity of some new 3-substituted androstano[17,16-c]-5′-aryl-pyrazoline and their derivatives. Bioorganic & Medicinal Chemistry 2006, 14, 373. <https://doi.org/10.1016/j.bmc.2005.08.024>
- Amr Abdel-Galil E., Abdulla Mohamed M.: Anti-inflammatory profile of some synthesized heterocyclic pyridone and pyridine derivatives fused with steroidal structure. Bioorganic & Medicinal Chemistry 2006, 14, 4341. <https://doi.org/10.1016/j.bmc.2006.02.045>
- Amr Abdel-Galil E., Mohamed Ashraf M., Mohamed Salwa F., Abdel-Hafez Nagla A., Hammam Abu El-Fotooh G.: Anticancer activities of some newly synthesized pyridine, pyrane, and pyrimidine derivatives. Bioorganic & Medicinal Chemistry 2006, 14, 5481. <https://doi.org/10.1016/j.bmc.2006.04.045>
- Amr Abd El‐Galil E., Sayed Hayam H., Abdulla Mohamed M.: Synthesis and Reactions of Some New Substituted Pyridine and Pyrimidine Derivatives as Analgesic, Anticonvulsant and Antiparkinsonian Agents. Archiv der Pharmazie 2005, 338, 433. <https://doi.org/10.1002/ardp.200500982>
- Hassan Saad S.M., Abou Ghalia M.H., Amr Abdel-Galil E., Mohamed Ayman H.K.: Novel thiocyanate-selective membrane sensors based on di-, tetra-, and hexa-imidepyridine ionophores. Analytica Chimica Acta 2003, 482, 9. <https://doi.org/10.1016/S0003-2670(03)00172-7>
- Amr Abd El‐Galil, Abd El‐Salam Osama I., Attia Abd El‐Hamid, Stibor Ivan: ChemInform Abstract: Synthesis of New Potential Bis‐Intercalators Based on Chiral Pyridine‐2,6‐dicarboxamides. ChemInform 1999, 30. <https://doi.org/10.1002/chin.199931234>