Collect. Czech. Chem. Commun.
2000, 65, 117-121
https://doi.org/10.1135/cccc20000117
Enzymatic Preparation of Lysergol β-D-Glucuronide
David E. Stevensona, Vladimír Křenb,*, Petr Haladab and Petr Sedmerab
a Industrial Research Ltd, Gracefield Road, P.O. Box 31-310, Lower Hutt, New Zealand
b Institute of Microbiology, Academy of Sciences of the Czech Republic, Laboratory of Biotransformation, Vídeňská 1083, CZ 142 20 Prague 4, Czech Republic
Abstract
Enzymatic synthesis of lysergol β-D-glucuronide (2) using ovine microsomal uridine 5'-diphosphoglucuronyl transferase and uridine 5'-diphosphoglucuronic acid (Na3-salt) is demonstrated.
Keywords: Ergot alkaloids; Lysergol; β-D-Glucuronide; Conjugation; Glycosidation; Biocatalysis.
References: 12 live references.
