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Collect. Czech. Chem. Commun. 2001, 66, 1698-1706
https://doi.org/10.1135/cccc20011698

Interactions of 1-[(S)-3-Hydroxy-2-(phosphonomethoxy)propyl]cytosine (Cidofovir) Diphosphate with DNA Polymerases α, δ and ε*

Gabriel Birkuš, Ivan Votruba*, Miroslav Otmar and Antonín Holý

Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Flemingovo nám. 2, 166 10 Prague 6, Czech Republic

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  • Špak J., Holý A., Pavingerová D., Votruba I., Špaková V., Petrzik K.: New in vitro method for evaluating antiviral activity of acyclic nucleoside phosphonates against plant viruses. Antivir Res 2010, 88, 296. <https://doi.org/10.1016/j.antiviral.2010.09.019>
  • Wolfgang Grushenka H. I., Shibata Riri, Wang Jianying, Ray Adrian S., Wu Sylvia, Doerrfler Edward, Reiser Hans, Lee William A., Birkus Gabriel, Christensen Neil D., Andrei Graciela, Snoeck Robert: GS-9191 Is a Novel Topical Prodrug of the Nucleotide Analog 9-(2-Phosphonylmethoxyethyl)Guanine with Antiproliferative Activity and Possible Utility in the Treatment of Human Papillomavirus Lesions. Antimicrob Agents Chemother 2009, 53, 2777. <https://doi.org/10.1128/AAC.00103-09>
  • Holý Antonin: Synthesis of Acyclic Nucleoside Phosphonates. CP Nucleic Acid Chemistry 2005, 22. <https://doi.org/10.1002/0471142700.nc1402s22>
  • Birkus Gabriel, Rejman Dominik, Otmar Miroslav, Votruba Ivan, Rosenberg Ivan, Holy Antonin: The Substrate Activity of (S)-9-[3-Hydroxy-(2-phosphonomethoxy)Propyl]Adenine Diphosphate toward DNA Polymerases α, δ and ε. Antivir Chem Chemother 2004, 15, 23. <https://doi.org/10.1177/095632020401500103>
  • Fernández-Botello Alfonso, Holý Antonı́n, Moreno Virtudes, Sigel Helmut: Stability and structure of binary and ternary metal ion complexes in aqueous solution of the quaternary 1-[2-(phosphonomethoxy)ethyl] derivative of 2,4-diaminopyrimidine (PMEDAPy−). Properties of an acyclic nucleotide analogue. Polyhedron 2003, 22, 1067. <https://doi.org/10.1016/S0277-5387(03)00093-7>
  • Birkus Gabriel, Votruba Ivan, Otmar Miroslav, Holy Antonin: ChemInform Abstract: Interactions of 1‐[(S)‐3‐Hydroxy‐2‐(phosphonomethoxy)propyl]cytosine (Cidofovir) Diphosphate with DNA Polymerases α, δ and ε*. ChemInform 2002, 33. <https://doi.org/10.1002/chin.200225204>