Collect. Czech. Chem. Commun.
2004, 69, 703-714
https://doi.org/10.1135/cccc20040703
Characterisation of Mutated Proteinases Derived from HIV-Positive Patients: Enzyme Activity, Vitality and Inhibition
Milan Kožíšeka,b, Jana Prejdováa,b, Milan Součeka, Ladislav Machalac, Marie Staňkovác, Marek Linkad, Marie Brůčkovád and Jan Konvalinkaa,b,*
a Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Flemingovo nám. 2, 166 10 Prague 6, Czech Republic
b Department of Biochemistry, Faculty of Science, Charles University in Prague, Hlavova 2030, 128 43 Prague 2, Czech Republic
c AIDS Center at the Clinic of Infectious Diseases, Faculty Clinic Bulovka, Budínova 2, 180 00 Prague 8, Czech Republic
d National Institutes of Public Health, National Reference Laboratory on AIDS, Šrobárova 48, 100 42 Prague 10, Czech Republic
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- Maseko Sibusiso B., Padayachee Eden, Govender Thavendran, Sayed Yasien, Kruger Gert, Maguire Glenn E.M., Lin Johnson: I36T↑T mutation in South African subtype C (C-SA) HIV-1 protease significantly alters protease-drug interactions. Biological Chemistry 2017, 398, 1109. <https://doi.org/10.1515/hsz-2017-0107>
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- Šašková Klára Grantz, Kožíšek Milan, Lepšík Martin, Brynda Jiří, Řezáčová Pavlína, Václavíková Jana, Kagan Ron M., Machala Ladislav, Konvalinka Jan: Enzymatic and structural analysis of the I47A mutation contributing to the reduced susceptibility to HIV protease inhibitor lopinavir. Protein Science 2008, 17, 1555. <https://doi.org/10.1110/ps.036079.108>
- Kožíšek Milan, Bray Jenelle, Řezáčová Pavlína, Šašková Klára, Brynda Jiří, Pokorná Jana, Mammano Fabrizio, Rulíšek Lubomír, Konvalinka Jan: Molecular Analysis of the HIV-1 Resistance Development: Enzymatic Activities, Crystal Structures, and Thermodynamics of Nelfinavir-resistant HIV Protease Mutants. Journal of Molecular Biology 2007, 374, 1005. <https://doi.org/10.1016/j.jmb.2007.09.083>
