Collect. Czech. Chem. Commun.
2004, 69, 1506-1516
https://doi.org/10.1135/cccc20041506
Effects of 3α-Amino-5α-pregnan-20-one on GABAA Receptor: Synthesis, Activity and Cytotoxicity
Libor Matyáša, Alexander Kasala,*, Zoila Babot Rierab and Cristina E. Sunolb
a Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Flemingovo nám. 2, 166 10 Prague 6, Czech Republic
b Departament de Neuroquímica, Institut d'Investigacions Biomédiques de Barcelona, CSIC (IDIBAPS), E-08036 Barcelona, Spain
Crossref Cited-by Linking
- Badmus J. A., Ekpo O. E., Hussein A. A., Meyer M., Hiss D. C.: Cytotoxic and cell cycle arrest properties of two steroidal alkaloids isolated from Holarrhena floribunda (G. Don) T. Durand & Schinz leaves. BMC Complement Altern Med 2019, 19. <https://doi.org/10.1186/s12906-019-2521-9>
- Gans Markus, Bracher Franz: First total synthesis of the marine steroid alkaloid plakinamine B. Tetrahedron 2014, 70, 1084. <https://doi.org/10.1016/j.tet.2013.11.065>
- Slavíková Barbora, Bujons Jordi, Matyáš Libor, Vidal Miguel, Babot Zoila, Krištofíková Zdena, Suñol Cristina, Kasal Alexander: Allopregnanolone and Pregnanolone Analogues Modified in the C Ring: Synthesis and Activity. J. Med. Chem. 2013, 56, 2323. <https://doi.org/10.1021/jm3016365>
- Hitchin James R., Hamilton Niall M., Jordan Allan M., Lyons Amanda J., Ogilvie Donald J.: A novel scalable and stereospecific synthesis of 3α- and 3β-amino-5α-androstan-17-ones and 3α- and 3β-amino-5α-pregnan-20-ones. Tetrahedron Letters 2012, 53, 2868. <https://doi.org/10.1016/j.tetlet.2012.03.124>
- Kumar Manmeet, Rawat Preeti, Khan Mohammad Faheem, Rawat Arun Kumar, Srivastava Arvind Kumar, Maurya Rakesh: Aza-annulation on the 16-dehydropregnenolone, via tandem intermolecular Aldol process and intramolecular Michael addition. Biorg Med Chem Lett 2011, 21, 2232. <https://doi.org/10.1016/j.bmcl.2011.02.112>
- Vidrna Lukáš, Černý Ivan, Pouzar Vladimír, Borovská Jiřina, Vyklický Vojtěch, Vyklický Ladislav, Chodounská Hana: Azido analogs of neuroactive steroids. Steroid 2011, 76, 1043. <https://doi.org/10.1016/j.steroids.2011.04.008>
- Sethi Arun, Maurya Atul, Tewari Vibha, Srivastava Sanjay, Faridi Shaheen, Bhatia Gitika, Khan M.M., Khanna A.K., Saxena J.K.: Expeditious and convenient synthesis of pregnanes and its glycosides as potential anti-dyslipidemic and anti-oxidant agents. biorg med chem 2007, 15, 4520. <https://doi.org/10.1016/j.bmc.2007.04.022>
- Matyas Libor, Pohl Radek, Kasal Alexander: Neighboring Group Participation in 12,20-Dioxopregnanes. Natural Product Communications 2007, 2. <https://doi.org/10.1177/1934578X0700201108>
- Hanson James R.: Steroids: partial synthesis in medicinal chemistry. Nat. Prod. Rep. 2006, 23, 100. <https://doi.org/10.1039/B512848J>
- Kasal Alexander, Matyáš Libor, Buděšínský Miloš: Neurosteroid analogues: synthesis of 6-aza-allopregnanolone. Tetrahedron 2005, 61, 2269. <https://doi.org/10.1016/j.tet.2005.01.055>
- Nawaz Khan Sharaf, Bae Seon-Yun, Kim Hong-Seok: A highly stereoselective reductive amination of 3-ketosteroid with amines: an improved synthesis of 3α-aminosteroid. Tetrahetron Lett 2005, 46, 7675. <https://doi.org/10.1016/j.tetlet.2005.09.051>
- Matyas Libor, Kasal Alexander, Babot Riera Zoila, Sunol Cristina E.: On Steroids. Part 417. Effects of 3α‐Amino‐5α‐pregnan‐20‐one on GABAA Receptor: Synthesis, Activity and Cytotoxicity. ChemInform 2004, 35. <https://doi.org/10.1002/chin.200452166>
- Černý Ivan, Havlíková Helena, Hill Martin, Hampl Richard, Pouzar Vladimír: Synthetic Approach to 5α-Pregnanolone 19-[O-(Carboxymethyl)oxime] Derivatives. Collect. Czech. Chem. Commun. 2004, 69, 1805. <https://doi.org/10.1135/cccc20041805>