Collect. Czech. Chem. Commun.
2005, 70, 339-349
https://doi.org/10.1135/cccc20050339
Novel Method for Preparation of Highly Substituted 6-Arylpurines by Reactions of 6-Alkynylpurines with Zirconacyclopentadienes
Pavel Tureka,b, Martin Kotoraa,b,*, Michal Hoceka,* and Ivan Votrubaa
a Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Flemingovo nám. 2, 166 10 Prague 6, Czech Republic
b Department of Organic and Nuclear Chemistry, Faculty of Science, Charles University, Hlavova 8, 128 43 Prague 2, Czech Republic
Individual author index pages
Other CCCC articles of these authors
- Gabriel Birkuš, Ivan Votruba, Antonín Holý and Berta Otová
HPMPApp as a substrate toward replicative DNA polymerases α, δ and ε
Symposium Series 1999, Vol. 2, pp. 289–293 [Abstract]
Published online 2016-05-08 23:33:04 - Romana Krejčová, Květoslava Horská, Ivan Votruba and Antonín Holý
Phosphorylation of enantiomers of HPMPG
Symposium Series 1999, Vol. 2, pp. 286–288 [Abstract]
Published online 2016-05-08 23:32:58 - Michal Česnek, Michal Hocek and Antonín Holý
Cross-coupling reactions of 2-amino-6-halopurine derivatives with organometallic reagents leading to 6-alkylated purine acyclic nucleotide analogues
Symposium Series 1999, Vol. 2, pp. 255–256 [Abstract]
Published online 2016-05-08 23:31:50 - Miroslav Otmar, Ivan Votruba and Antonín Holý
An alternative synthesis of HPMPC and HPMPA diphosphoryl derivatives
Symposium Series 1999, Vol. 2, pp. 252–254 [Abstract]
Published online 2016-05-08 23:31:40 - Michal Hocek, Martina Havelková, Dalimil Dvořák, Antonín Holý and Ivan Votruba
Synthesis of 6-phenylpurine bases and nucleosides by Suzuki–Miyaura cross-coupling reactions of 6-chloropurines with substituted phenylboronic acids
Symposium Series 1999, Vol. 2, pp. 27–30 [Abstract]
Published online 2016-05-08 20:40:17 - Pavel Turek, Michal Hocek and Martin Kotora
[2+2+2]-co-Cyclotrimerization of 6-alkynylpurines with diynes: A method for preparation 6-arylpurines
Symposium Series 2002, Vol. 5, pp. 389–390 [Abstract]
Published online 2016-01-25 20:52:00 - Michal Hocek
Synthesis of carba-analogues of myoseverin
Symposium Series 2002, Vol. 5, pp. 324–325 [Abstract]
Published online 2016-01-25 20:42:22 - Miroslav Otmar, Milena Masojídková, Ivan Votruba and Antonín Holý
Synthesis and cytostatic activity of 2,6-diamino-9-benzyl-9-deazapurine and related compounds
Symposium Series 2002, Vol. 5, pp. 38–39 [Abstract]
Published online 2016-01-25 20:38:21 - Michal Hocek, Dalimil Dvořák and Martina Havelková
Covalently linked purine dimers or trimers and purine–pyrimidine conjugates – analogues of nucleobase-pairs or triplets
Symposium Series 2002, Vol. 5, pp. 36–37 [Abstract]
Published online 2016-01-25 20:38:15 - Milan Vrabel, Ivan Rosenberg and Michal Hocek
Synthesis of modified nucleosides and oligonucleotides bearing bipyridine or phenanthroline ligands
Symposium Series 2005, Vol. 7, pp. 485–486 [Abstract]
Published online 2015-11-08 11:58:56 - Markéta Schinkmanová, Ivan Votruba and Antonín Holý
N6-methyl-AMP hydrolase activates N6-substituted purine ANPs
Symposium Series 2005, Vol. 7, pp. 463–464 [Abstract]
Published online 2015-11-08 11:58:20 - Petr Novák, Michal Hocek and Martin Kotora
Synthesis of C-arylribosides by catalytic [2+2+2]-cyclotrimerization reaction
Symposium Series 2005, Vol. 7, pp. 445–446 [Abstract]
Published online 2015-11-08 11:57:49 - Radim Nencka, Ivan Votruba, Hubert Hřebabecký, Eva Tloušťová, Květa Horská, Milena Masojídková and Antonín Holý
Design and synthesis of 5,6-disubstituted uracil derivatives as potent inhibitors of thymidine phosphorylase
Symposium Series 2005, Vol. 7, pp. 441–442 [Abstract]
Published online 2015-11-08 11:57:40 - Martin Kuchař and Michal Hocek
Synthesis of purines bearing functionalized C-substituents by nucleophilic additions to 6-ethynyl- or 6-vinylpurines
Symposium Series 2005, Vol. 7, pp. 423–424 [Abstract]
Published online 2015-11-08 11:57:11 - Petr Kočalka, Markéta Rinnová, Václav Vaněk, Dominik Rejman, Ivan Votruba, Ivana Tomečková, Šárka Králíková, Magdalena Petrová, Ondřej Páv, Radek Pohl, Miloš Buděšínský, Radek Liboska, Zdeněk Točík and Ivan Rosenberg
Novel nucleoside phosphonic acids-based inhibitors of thymidine phosphorylase
Symposium Series 2005, Vol. 7, pp. 415–416 [Abstract]
Published online 2015-11-08 11:56:57 - Miroslav Hájek, Naděžda Matulová, Ivan Votruba, Antonín Holý and Eva Tloušťová
Acyclic nucleoside phosphonates and human telomerase inhibition
Symposium Series 2005, Vol. 7, pp. 373–374 [Abstract]
Published online 2015-11-08 11:55:35 - Pavel Turek, Michal Hocek and Martin Kotora
Cocyclotrimerization of 6-alkynylpurines with diynes as a novel approach to biologically active 6-arylpurines
Symposium Series 2005, Vol. 7, pp. 279–282 [Abstract]
Published online 2015-11-08 11:53:57 - Jan Štambaský, Pavel Kočovský and Michal Hocek
Towards a novel approach to C-nucleosides
Symposium Series 2005, Vol. 7, pp. 277–278 [Abstract]
Published online 2015-11-08 11:53:52 - Peter Šilhár, Radek Pohl, Ivan Votruba and Michal Hocek
Synthesis and transformations of 6-(hydroxymethyl)purines
Symposium Series 2005, Vol. 7, pp. 221–224 [Abstract]
Published online 2015-11-08 11:52:45 - Petr Čapek and Michal Hocek
Synthesis of (purin-6-yl)amino acids
Symposium Series 2005, Vol. 7, pp. 217–220 [Abstract]
Published online 2015-11-08 11:52:40 - Michal Hocek and Dana Hocková
Regioselective cross-coupling reactions in the synthesis of multisubstituted purine bases and nucleosides
Symposium Series 2005, Vol. 7, pp. 213–216 [Abstract]
Published online 2015-11-08 11:52:35 - Ivan Rosenberg, Ivan Barvik, Miloš Buděšínský, Petr Kočalka, Šárka Králíková, Radek Liboska, Ondřej Pačes, Ondřej Páv, Magdalena Petrová, Radek Pohl, Martina Pressová, Dominik Rejman, Ivan Votruba and Zdeněk Točík
Nucleoside phosphonic acids and related oligonucleotides: Structural diversity vs biological properties
Symposium Series 2005, Vol. 7, pp. 153–157 [Abstract]
Published online 2015-11-08 11:51:38 - Martin Štefko and Michal Hocek
A modular methodology for the synthesis of 3- and 4-substituted benzene and aniline C-ribonucleosides
Symposium Series 2008, Vol. 10, pp. 455–456 [Abstract]
Published online 2015-10-30 18:45:05 - Jan Riedl and Michal Hocek
Synthesis of modified fluorescent nucleosides
Symposium Series 2008, Vol. 10, pp. 442–443 [Abstract]
Published online 2015-10-30 18:44:40 - David Mařák, Miroslav Otmar, Martin Dračínský, Ivan Votruba and Antonín Holý
Nucleosides and nucleotides containing 8-aza-7,9-dideazaxanthine
Symposium Series 2008, Vol. 10, pp. 426–428 [Abstract]
Published online 2015-10-30 18:44:11 - Lubica Kalachova and Michal Hocek
Synthesis of modified nucleosides and nucleoside triphosphates bearing oligopyridine ligands
Symposium Series 2008, Vol. 10, pp. 366–368 [Abstract]
Published online 2015-10-30 18:42:13 - Zbyněk Hasník and Michal Hocek
Synthesis of (purin-6-yl)acetates and their transformations
Symposium Series 2008, Vol. 10, pp. 352–354 [Abstract]
Published online 2015-10-30 18:41:46 - Igor Čerňa and Michal Hocek
Direct C–H arylation of purines and purine nucleosides
Symposium Series 2008, Vol. 10, pp. 327–329 [Abstract]
Published online 2015-10-30 18:40:48 - Jan Bárta and Michal Hocek
Modular synthesis of 5-substituted thiophen-2-yl C-2'-deoxyribonucleosides
Symposium Series 2008, Vol. 10, pp. 313–314 [Abstract]
Published online 2015-10-30 18:40:16 - Radim Nencka, Hubert Hřebabecký, Ivan Votruba, Martin Dračínský and Antonín Holý
Metalation of 6-halo-2,4-dimethoxypyrimidines as the key step for the synthesis of biologicaly active compounds
Symposium Series 2008, Vol. 10, pp. 249–253 [Abstract]
Published online 2015-10-30 18:38:37 - Karel Pomeisl, Antonín Holý, Ivan Votruba, Radim Nencka and Radek Pohl
Facile syntheses of pyrimidine acyclic nucleoside phosphonates and their potential evaluation for biomedical applications
Symposium Series 2008, Vol. 10, pp. 201–205 [Abstract]
Published online 2015-10-30 18:37:39 - Milan Vrabel and Michal Hocek
Synthesis of modified nucleosides, nucleotides and oligonucleotides bearing metal complexes
Symposium Series 2008, Vol. 10, pp. 182–185 [Abstract]
Published online 2015-10-30 18:37:15 - Hana Cahová, Luděk Havran, Petra Brázdilová, Hana Pivoňková, Miroslav Fojta and Michal Hocek
Aminophenyl- and nitrophenyl-labeled DNA. Synthesis by polymerase incorporation of nucleoside triphosphates and electrochemical properties
Symposium Series 2008, Vol. 10, pp. 178–181 [Abstract]
Published online 2015-10-30 18:37:09 - Nicolas Joubert, Jan Bárta, Milan Urban and Michal Hocek
Modular methodology for the syntheses of various aryl C-2'-deoxyribonucleosides
Symposium Series 2008, Vol. 10, pp. 173–177 [Abstract]
Published online 2015-10-30 18:37:03 - Petr Novák, Michal Hocek and Martin Kotora
New approaches to synthesis of C-deoxyribosides starting from C-alkynyldeoxyribosides
Symposium Series 2008, Vol. 10, pp. 168–172 [Abstract]
Published online 2015-10-30 18:36:57 - Michal Hocek, Peter Šilhár, Martin Kuchař, Zbyněk Hasník and Vítězslav Bambuch
Purine bases and nucleosides bearing functionalized C-substituents in position 6. Synthesis and biological activities
Symposium Series 2008, Vol. 10, pp. 164–167 [Abstract]
Published online 2015-10-30 18:36:52 - Michal Tichý and Michal Hocek
Synthesis of 4-(het)aryl pyrimido[4,5-b]indole ribonucleosides
Symposium Series 2011, Vol. 12, pp. 475–476 [Abstract]
Published online 2015-08-20 10:24:59 - Petr Jansa, Petr Špaček, Antonín Holý, Ivan Votruba and Zlatko Janeba
Efficient one-pot synthesis of polysubstituted 6-[(1H-1,2,3-triazol-1-yl)methyl]uracils through the "click" protocol
Symposium Series 2011, Vol. 12, pp. 467–468 [Abstract]
Published online 2015-08-20 10:24:43 - Ivan Šnajdr, Zbyněk Janoušek and Martin Kotora
Synthesis of novel C-(o-carboranyl)-2-deoxy-D-ribose conjugates
Symposium Series 2011, Vol. 12, pp. 465–466 [Abstract]
Published online 2015-08-20 10:24:38 - Veronika Raindlová and Michal Hocek
Direct enzymatic synthesis of aldehyde-functionalized DNA and its conjugation with hydrazines and amines
Symposium Series 2011, Vol. 12, pp. 441–443 [Abstract]
Published online 2015-08-20 10:23:46 - Hana Pivoňková, Kateřina Němcová, Petra Horáková, Luděk Havran, Hana Macíčková-Cahová, Michal Hocek and Miroslav Fojta
Tail labelled oligonucleotide probes for the detection of DNA-protein interactions
Symposium Series 2011, Vol. 12, pp. 435–437 [Abstract]
Published online 2015-08-20 10:23:34 - Pavel Kielkowski and Michal Hocek
Polymerase synthesis of modified DNA containing cytosine in major groove
Symposium Series 2011, Vol. 12, pp. 359–360 [Abstract]
Published online 2015-08-20 10:19:01 - Lubica Kalachova and Michal Hocek
Synthesis of nucleotides bearing oligopyridine ligands and their incorporation into DNA
Symposium Series 2011, Vol. 12, pp. 357–358 [Abstract]
Published online 2015-08-20 10:18:56 - Filip Hessler and Martin Kotora
Synthesis and rearrangements of Dewar benzene deoxyribosides
Symposium Series 2011, Vol. 12, pp. 334–335 [Abstract]
Published online 2015-08-20 10:12:54 - Miroslava Čerňová and Michal Hocek
Dichotomy in regioselectivity of Pd-catalyzed direct C–H arylation of protected uracils
Symposium Series 2011, Vol. 12, pp. 314–316 [Abstract]
Published online 2015-08-20 10:12:11 - Jan Bárta and Michal Hocek
Modular synthesis of 5-substituted thiophene and furan C-nucleosides and their analogues
Symposium Series 2011, Vol. 12, pp. 300–301 [Abstract]
Published online 2015-08-20 10:11:36 - Jana Balintová, Luděk Havran, Miroslav Fojta and Michal Hocek
Synthesis of nucleosides and nucleoside triphosphates bearing anthraquinone substituents as redox probes and their enzymatic incorporation to DNA
Symposium Series 2011, Vol. 12, pp. 297–299 [Abstract]
Published online 2015-08-20 10:11:31 - Jan Riedl and Michal Hocek
Synthesis of biaryl-substituted fluorescent nucleosides and nucleoside triphosphates and their incorporation to DNA
Symposium Series 2011, Vol. 12, pp. 233–235 [Abstract]
Published online 2015-08-20 10:02:23 - Pavla Perlíková, Petr Nauš, Aurelie Bourderioux and Michal Hocek
Hetaryl derivatives of 7-deazapurine ribonucleosides: potent cytostatic agents
Symposium Series 2011, Vol. 12, pp. 194–198 [Abstract]
Published online 2015-08-20 10:00:49 - Tomáš Kubelka, Martin Štefko, Jan Bárta, Nicolas Joubert, Milan Urban, Hubert Chapuis and Michal Hocek
Development of a general and modular approach to C-nucleosides
Symposium Series 2011, Vol. 12, pp. 180–183 [Abstract]
Published online 2015-08-20 10:00:32 - Miroslav Fojta, Luděk Havran, Petra Horáková, Hana Pivoňková, Pavel Kostečka, Hana Macíčková, Veronika Raindlová, Milan Vrabel and Michal Hocek
Redox labelling of nucleic acids for analyzing nucleotide sequences and monitoring DNA-protein interactions
Symposium Series 2011, Vol. 12, pp. 155–158 [Abstract]
Published online 2015-08-20 09:59:54 - Michal Hocek, Hana Macíčková-Cahová, Pavel Kielkowski, Veronika Raindlová, Lubica Kalachova, Jan Riedl, Jana Balintová and Petra Ménová
Polymerase construction of base-modified DNA for chemical biology
Symposium Series 2011, Vol. 12, pp. 152–154 [Abstract]
Published online 2015-08-20 09:59:48 - Zuzana Vaníková and Michal Hocek
Polymerase synthesis of new photocaged DNA
Symposium Series 2014, Vol. 14, pp. 392–393 [Abstract]
Published online 2015-07-06 23:09:39 - Michal Tichý and Michal Hocek
Synthesis and biological activity of thiophene fused 7-deazapurine ribonucleosides
Symposium Series 2014, Vol. 14, pp. 385–386 [Abstract]
Published online 2015-07-06 23:09:23 - Anna Simonova, Luděk Havran, Miroslav Fojta and Michal Hocek
New oxidative labels for electrochemical detection of DNA
Symposium Series 2014, Vol. 14, pp. 365–366 [Abstract]
Published online 2015-07-06 23:08:32 - Petr Orság, Hana Pivoňková, Jan Riedl, Michal Hocek and Miroslav Fojta
Utilisation of enzymatic labelling with 4-aminophtalimide and 4-hydroxybenzylideneimidazolinone fluorescent derivates for monitoring of DNA-protein interaction
Symposium Series 2014, Vol. 14, pp. 340–341 [Abstract]
Published online 2015-07-06 23:07:27 - Petra Ménová and Michal Hocek
Preparation of modified oligonucleotides by nicking enzyme amplification reaction
Symposium Series 2014, Vol. 14, pp. 324–325 [Abstract]
Published online 2015-07-06 23:06:55 - Michaela Mačková and Michal Hocek
Vinyl-modified DNA and its cleavage by restriction endonucleases
Symposium Series 2014, Vol. 14, pp. 318–319 [Abstract]
Published online 2015-07-06 23:06:39 - Pavel Kielkowski and Michal Hocek
Competitive incorporations of modified versus natural nucleotides by DNA polymerases
Symposium Series 2014, Vol. 14, pp. 295–296 [Abstract]
Published online 2015-07-06 23:05:36 - Miroslav Fojta, Aleš Daňhel, Petra Horáková, Medard Plucnara, Hana Pivoňková, Luděk Havran, Pavlína Vidláková, Veronika Raindlová, Jana Balintová, Hana Macíčková-Cahová and Michal Hocek
Electrochemical analysis of DNA using switchable redox moieties
Symposium Series 2014, Vol. 14, pp. 264–266 [Abstract]
Published online 2015-07-06 23:04:13 - Jitka Daďová, Petr Orság, Radek Pohl, Marie Brázdová, Miroslav Fojta and Michal Hocek
Study of DNA-protein interactions by cross-link formation using aqueous Michael addition
Symposium Series 2014, Vol. 14, pp. 240–241 [Abstract]
Published online 2015-07-06 23:03:09 - Jana Balintová, Marie Brázdová, Luděk Havran, Miroslav Fojta and Michal Hocek
Redox labeling and redox coding of nucleic acids
Symposium Series 2014, Vol. 14, pp. 229–230 [Abstract]
Published online 2015-07-06 23:02:33 - Jana Balintová, Jitka Daďová, Pavel Kielkowski, Petra Ménová, Zuzana Vaníková, Jan Riedl, Veronika Raindlová, Miroslav Fojta and Michal Hocek
Polymerase synthesis of base-modified DNA: new methods and new applications
Symposium Series 2014, Vol. 14, pp. 66–67 [Abstract]
Published online 2015-07-06 22:57:12 - Martin Křováček, Hana Dvořáková, Ivan Votruba, Ivana Císařová and Dalimil Dvořák*
6-Alkynylpurines bearing electronacceptor substituents: Preparation, reactivity in cycloaddition reactions and cytostatic activity
2011, Vol. 76, Issue 12, pp. 1487–1527 [Abstract] - Petr Jansa*, Petr Špaček, Ivan Votruba, Petra Břehová, Martin Dračínský, Blanka Klepetářová and Zlatko Janeba
Efficient one-pot synthesis of polysubstituted 6-[(1H-1,2,3-triazol-1-yl)methyl]uracils through the “click” protocol
2011, Vol. 76, Issue 9, pp. 1121–1131 [Abstract] - Petr Nauš, Pavla Perlíková, Radek Pohl and Michal Hocek*
Sugar-modified derivatives of cytostatic 6-(het)aryl-7-deazapurine nucleosides: 2′-C-methylribonucleosides, arabinonucleosides and 2′-deoxy-2′-fluoroarabinonucleosides
2011, Vol. 76, Issue 8, pp. 957–988 [Abstract] - Aneta Kadlčíková, Klára Vlašaná and Martin Kotora*
Enantioselective epoxide ring opening catalyzed by bis(tetrahydroisoquinoline) N,N′-dioxides
2011, Vol. 76, Issue 5, pp. 415–422 [Abstract] - Ivan Votruba*, Jana Trýznová, Petra Břehová, Eva Tloušťová, Květoslava Horská, Jindřich Fanfrlík, Ondřej Přenosil and Antonín Holý
Inhibition of human purine nucleoside phosphorylase by tenofovir phosphate congeners
2010, Vol. 75, Issue 12, pp. 1249–1257 [Abstract] - Vojtěch Balšánek, Lucie Tichotová, Jiří Kuneš, Marcel Špulák, Milan Pour*, Ivan Votruba and Vladimír Buchta
Cytostatic tetrazole–butenolide conjugates: linking tetrazole and butenolide rings via stille coupling and biological activity of the target substances
2009, Vol. 74, Issue 7-8, pp. 1161–1178 [Abstract] - Zbyněk Hasník, Radek Pohl, Blanka Klepetářová and Michal Hocek*
Synthesis of (purin-6-yl)acetates and their transformations to 6-(2-hydroxyethyl)- and 6-(carbamoylmethyl)purines
2009, Vol. 74, Issue 7-8, pp. 1035–1059 [Abstract] [Full text pdf] - Petr Novák and Martin Kotora*
Rh- and Ru-complex-catalyzed dimerization of arylethynes in aqueous environment
2009, Vol. 74, Issue 3, pp. 433–442 [Abstract] - Petr Nauš, Martin Kuchař and Michal Hocek*
Cytostatic and Antiviral 6-Arylpurine Ribonucleosides IX. Synthesis and Evaluation of 6-Substituted 3-Deazapurine Ribonucleosides
2008, Vol. 73, Issue 5, pp. 665–678 [Abstract] [Full text pdf] - Markéta Schinkmanová*, Ivan Votruba, Riri Shibata, Bin Han, Xiaohong Liu, Tomas Cihlar and Antonín Holý
Human N6-Methyl-AMP/DAMP Aminohydrolase (Abacavir 5'-Monophosphate Deaminase) is Capable of Metabolizing N6-Substituted Purine Acyclic Nucleoside Phosphonates
2008, Vol. 73, Issue 2, pp. 275–291 [Abstract] - Michal Hocek*, Peter Šilhár and Radek Pohl
Cytostatic and Antiviral 6-Arylpurine Ribonucleosides VIII. Synthesis and Evaluation of 6-Substituted Purine 3'-Deoxyribonucleosides
2006, Vol. 71, Issue 10, pp. 1484–1496 [Abstract] - Peter Šilhár, Radek Pohl, Ivan Votruba, Blanka Klepetářová and Michal Hocek*
Synthesis of 6-Amino-, 6-Methyl- and 6-Aryl-2-(hydroxymethyl)purine Bases and Nucleosides
2006, Vol. 71, Issue 6, pp. 788–803 [Abstract] - Karel Pomeisl*, Ivan Votruba, Antonín Holý and Radek Pohl
Syntheses of Base and Side-Chain Modified Pyrimidine 1-[2-(Phosphonomethoxy)propyl] Derivatives as Potent Inhibitors of Thymidine Phosphorylase (PD-ECGF) from SD-Lymphoma
2006, Vol. 71, Issue 4, pp. 595–624 [Abstract] - Marie Sobociková, Petr Štěpnička, Daniele Ramella and Martin Kotora*
Synthesis of 1-Alkanoyl-1'-(trifluoroacetyl)ferrocenes
2006, Vol. 71, Issue 2, pp. 190–196 [Abstract] - Květoslava Horská, Ivan Votruba* and Antonín Holý
Interaction of Phosphates of the Acyclic Nucleoside Phosphonates with Nucleoside Diphosphate Kinase from Yeast and Bovine Liver
2006, Vol. 71, Issue 1, pp. 35–43 [Abstract] - Peter Šilhár, Radek Pohl, Ivan Votruba and Michal Hocek*
Synthesis of 2-Substituted 6-(Hydroxymethyl)purine Bases and Nucleosides
2005, Vol. 70, Issue 10, pp. 1669–1695 [Abstract] - Karel Pomeisl*, Radek Pohl, Antonín Holý and Ivan Votruba
Simple Transformation of Thymine 1-[3-Hydroxy-2-(phosphonomethoxy)propyl] Derivatives to Their 1-[3-Fluoro-2-(phosphonomethoxy)propyl] Counterparts
2005, Vol. 70, Issue 9, pp. 1465–1481 [Abstract] - Petr Nauš, Ivan Votruba and Michal Hocek*
Covalent Analogues of DNA Base-Pairs and Triplets VII. Synthesis and Cytostatic Activity of Bis(purin-6-yl)acetylene and -diacetylene Nucleosides
2004, Vol. 69, Issue 10, pp. 1955–1970 [Abstract] - Alois Pískala*, Naeem B. Hanna, Milena Masojídková, Pavel Fiedler and Ivan Votruba
Synthesis of N4-Amino and N4-Hydroxy Derivatives of 5-Azacytidine. A Facile Rearrangement of the N4-Amino Derivative to 5-(3-β-D-Ribofuranosylureido)-1H-1,2,4-triazole
2004, Vol. 69, Issue 4, pp. 905–917 [Abstract] - Lenka Dufková, Hiroshi Matsumura, David Nečas, Petr Štěpnička, Filip Uhlík and Martin Kotora*
Reaction of Zirconacyclopentadienes with Ethynylferrocenes
2004, Vol. 69, Issue 2, pp. 351–364 [Abstract] - Martin Kotora, David Nečas and Petr Štěpnička*
Synthesis of Diferrocenylethyne by Molybdenum-Catalyzed Metathesis of 1-Ferrocenylprop-1-yne
2003, Vol. 68, Issue 10, pp. 1897–1903 [Abstract] - Michal Hocek*, Dana Hocková and Jan Štambaský
Cytostatic 6-Arylpurine Nucleosides V. Synthesis of 8-Substituted 6-Phenylpurine Ribonucleosides
2003, Vol. 68, Issue 5, pp. 837–848 [Abstract] - Petr Čapek, Miroslav Otmar*, Milena Masojídková, Ivan Votruba and Antonín Holý
A Facile Synthesis of 9-Deaza Analogue of Olomoucine
2003, Vol. 68, Issue 4, pp. 779–791 [Abstract] - Michal Hocek*, Hana Dvořáková and Ivana Císařová
Covalent Analogues of DNA Base-Pairs and Triplets V. Synthesis of Purine-Purine and Purine-Pyrimidine Conjugates Connected by Diverse Types of Acyclic Carbon Linkages
2002, Vol. 67, Issue 10, pp. 1560–1578 [Abstract] - Michal Hocek*, Irena G. Stará, Ivo Starý and Hana Dvořáková
Covalent Analogues of DNA Base-Pairs and Triplets IV. Synthesis of Trisubstituted Benzenes Bearing Purine and/or Pyrimidine Rings by Cyclotrimerization of 6-Ethynylpurines and/or 5-Ethynyl-1,3-dimethyluracil
2002, Vol. 67, Issue 8, pp. 1223–1235 [Abstract] - Michal Hocek*, Antonín Holý and Hana Dvořáková
Cytostatic 6-Arylpurine Nucleosides IV. Synthesis of 2-Substituted 6-Phenylpurine Ribonucleosides
2002, Vol. 67, Issue 3, pp. 325–335 [Abstract] - Gabriel Birkuš, Ivan Votruba*, Miroslav Otmar and Antonín Holý
Interactions of 1-[(S)-3-Hydroxy-2-(phosphonomethoxy)propyl]cytosine (Cidofovir) Diphosphate with DNA Polymerases α, δ and ε*
2001, Vol. 66, Issue 11, pp. 1698–1706 [Abstract] - Antonín Holý*, Ivan Votruba, Eva Tloušťová and Milena Masojídková
Synthesis and Cytostatic Activity of N-[2-(Phosphonomethoxy)alkyl] Derivatives of N6-Substituted Adenines, 2,6-Diaminopurines and Related Compounds
2001, Vol. 66, Issue 10, pp. 1545–1592 [Abstract] - Miroslav Otmar*, Milena Masojídková, Ivan Votruba and Antonín Holý
An Alternative Synthesis of HPMPC and HPMPA Diphosphoryl Derivatives
2001, Vol. 66, Issue 3, pp. 500–506 [Abstract] - Michal Hocek*, Antonín Holý, Ivan Votruba and Hana Dvořáková
Cytostatic 6-Arylpurine Nucleosides III. Synthesis and Structure-Activity Relationship Study in Cytostatic Activity of 6-Aryl-, 6-Hetaryl- and 6-Benzylpurine Ribonucleosides
2001, Vol. 66, Issue 3, pp. 483–499 [Abstract] - Michal Hocek*, Antonín Holý, Ivan Votruba and Hana Dvořáková
Cytostatic 6-Arylpurine Nucleosides II. Synthesis of Sugar-Modified Derivatives: 9-(2-Deoxy-β-D-erythro-pentofuranosyl)-, 9-(5-Deoxy-β-D-ribofuranosyl)- and 9-(2,3-Dihydroxypropyl)-6-phenylpurines
2000, Vol. 65, Issue 11, pp. 1683–1697 [Abstract] - Romana Krejčová, Květoslava Horská, Ivan Votruba* and Antonín Holý
Phosphorylation of Purine (Phosphonomethoxy)alkyl Derivatives by Mitochondrial AMP Kinase (AK2 Type) from L1210 Cells
2000, Vol. 65, Issue 10, pp. 1653–1668 [Abstract] - Michal Česnek, Michal Hocek* and Antonín Holý
Synthesis of Acyclic Nucleotide Analogues Derived from 2-Amino-6-C-substituted Purines via Cross-Coupling Reactions of 2-Amino-9-{2-[(diisopropoxyphosphoryl)methoxy]ethyl}-6-halopurines with Diverse Organometallic Reagents
2000, Vol. 65, Issue 8, pp. 1357–1373 [Abstract] - Martin Kotora, Yoshinori Noguchi and Tamotsu Takahashi*
Reactions of Zirconacyclopentadienes with Propargyl Halides Leading to (Buta-2,3-dien-1-yl)benzenes
1999, Vol. 64, Issue 7, pp. 1119–1124 [Abstract] - Romana Krejčová, Květoslava Horská, Ivan Votruba* and Antonín Holý
Isoenzymes of GMP Kinase from L1210 Cells: Isolation and Characterization
1999, Vol. 64, Issue 3, pp. 559–570 [Abstract] - Michal Hocek* and Antonín Holý
Perfluoroalkylation of 6-Iodopurines by Trimethyl(perfluoroalkyl)silanes. Synthesis of 6-(Perfluoroalkyl)purine Bases, Nucleosides and Acyclic Nucleotide Analogues
1999, Vol. 64, Issue 2, pp. 229–241 [Abstract] - Gabriel Birkuš, Pavel Kramata, Ivan Votruba, Berta Otová, Miroslav Otmar and Antonín Holý
Nonproteolyzed Form of DNA-Polymerase ε from T-Cell Spontaneous Lymphoma of Sprague-Dawley Inbred Rat: Isolation and Characterization
1998, Vol. 63, Issue 5, pp. 723–731 [Abstract] - Lenka Olšanská, Tomas Cihlar, Ivan Votruba* and Antonín Holý
Transport of Adefovir (PMEA) in Human T-Lymphoblastoid Cells
1997, Vol. 62, Issue 5, pp. 821–828 [Abstract] - Michal Hocek, Milena Masojídková and Antonín Holý
Synthesis of Acyclic Nucleotide Analogues Derived from 6-Hetarylpurines via Cross-Coupling Reactions of 9-[2-(Diethoxyphosphonylmethoxy)ethyl]-6-iodopurine with Hetaryl Organometallic Reagents
1997, Vol. 62, Issue 1, pp. 136–146 [Abstract] - Pavel Kramata, Gabriel Birkuš, Miroslav Otmar, Ivan Votruba and Antonín Holý
Structural features of acyclic nucleotide analogs conferring inhibitory effects on cellular replicative DNA polymerases
1996, Vol. 61, Special Issue, pp. S188–S191 [Abstract] - Antonín Holý, Zdeněk Zídek and Ivan Votruba
Inhibition of murine lymphocyte proliferation by N6-substituted acyclic purine nucleoside phosphonates
1996, Vol. 61, Special Issue, pp. S182–S187 [Abstract] - Romana Krejčová, Květoslava Horská, Ivan Votruba and Antonín Holý
Phosphorylation of phosphonomethoxyalkylguanines by GMP-kinase isoenzymes
1996, Vol. 61, Special Issue, pp. S134–S136 [Abstract] - Michal Hocek and Antonín Holý
Acyclic nucleotide analogues derived from 6-(1-aminoalkyl)purines
1996, Vol. 61, Special Issue, pp. S55–S58 [Abstract] - Michal Hocek, Milena Masojídková, Antonín Holý, Graciela Andrei, Robert Snoeck, Jan Balzarini and Erik De Clercq
Synthesis and Antiviral Activity of Acyclic Nucleotide Analogues Derived from 6-(Aminomethyl)purines and Purine-6-carboxamidines
1996, Vol. 61, Issue 10, pp. 1525–1537 [Abstract] - Milan Hájek, Martin Kotora, František Adámek, Reg Davis, Cecile Fischer and Warren A. C. Joshu
Catalyst Effects on the Stereoselectivity of Addition of Tetrachloromethane to 1,3-Cyclohexadiene
1996, Vol. 61, Issue 5, pp. 774–777 [Abstract] - Pavel Kramata, Jaroslav Černý, Gabriel Birkuš, Ivan Votruba, Berta Otová and Antonín Holý
DNA-Polymerases α, δ and ε from T-Cell Spontaneous Lymphoblastic Leukemia of Sprague-Dawley Inbred Rat: Isolation and Characterization
1995, Vol. 60, Issue 9, pp. 1555–1572 [Abstract] - Michal Hocek and Antonín Holý
A Facile Synthesis of 6-Cyanopurine Bases
1995, Vol. 60, Issue 8, pp. 1386–1389 [Abstract] - Michal Hocek, Milena Masojídková and Antonín Holý
Synthesis of Acyclic Nucleotide Analogues Derived from 2-(Aminomethyl)adenine and 2-(Aminomethyl)hypoxanthine
1995, Vol. 60, Issue 5, pp. 875–882 [Abstract] - Ivan Votruba, Antonín Holý, Hana Dvořáková, Jaroslav Günter, Dana Hocková, Hubert Hřebabecký, Tomas Cihlar and Milena Masojídková
Synthesis of 2-Deoxy-β-D-ribonucleosides and 2,3-Dideoxy-β-D-pentofuranosides on Immobilized Bacterial Cells
1994, Vol. 59, Issue 10, pp. 2303–2330 [Abstract] - Stanislav Böhm, Michal Hocek, Jan Němeček, Vladimír Havlíček and Josef Kuthan
Preparation and Spectroscopic Properties of Spirocyclic 1-Methyl-2,4,4,6-tetraaryl-1,4-dihydropyridines
1994, Vol. 59, Issue 5, pp. 1105–1114 [Abstract] - Stanislav Böhm, Michal Hocek, Stanislav Nešpůrek and Josef Kuthan
Photocolouration of 2,4,4,6-Tetraaryl-1,4-dihydropyridines: A Semiempirical Quantum Chemical Study
1994, Vol. 59, Issue 2, pp. 262–272 [Abstract] - Hana Dvořáková, Antonín Holý, Ivan Votruba and Milena Masojídková
Synthesis and Biological Effects of Acyclic Analogs of Deazapurine Nucleosides
1993, Vol. 58, Issue 3, pp. 629–648 [Abstract] - Martin Kotora, Milan Hájek and Christian Döbler
Addition of Tetrachloromethane to Styrene Catalyzed by Copper-Chiral Amine Complexes
1992, Vol. 57, Issue 12, pp. 2622–2628 [Abstract] - Pavel Kramata and Ivan Votruba
Enzymes of Human Herpesviruses
1992, Vol. 57, Issue 8, pp. 1577–1612 [Abstract] - Tomas Cihlar, Ivan Votruba, Květoslava Horská, Radek Liboska, Ivan Rosenberg and Antonín Holý
Metabolism of 1-(S)-(3-Hydroxy-2-phosphonomethoxypropyl)cytosine (HPMPC) in Human Embryonic Lung Cells
1992, Vol. 57, Issue 3, pp. 661–672 [Abstract] - Martin Kotora and Milan Hájek
Addition of Tetrachloromethane to 1,5-Hexadiene
1992, Vol. 57, Issue 2, pp. 393–396 [Abstract] - Katarina Šedivá, Ivan Votruba, Antonín Holý and Ivan Rosenberg
Purine nucleoside phosphorylase: Isolation and characterization
1990, Vol. 55, Issue 12, pp. 2987–2999 [Abstract] - Antonín Holý, Masahiko Nishizawa, Ivan Rosenberg and Ivan Votruba
The effect of phosphonylmethyl analogs of ribonucleoside 5'-diphosphates on (E. coli) polynucleotide phosphorylase catalyzed reactions
1987, Vol. 52, Issue 12, pp. 3042–3057 [Abstract] - Antonín Holý, Joachim König, Jiří Veselý, Dieter Cech, Ivan Votruba and Erik De Clercq
5'-O-Alkyl-5-fluorouridines: Synthesis and biological activity
1987, Vol. 52, Issue 6, pp. 1589–1608 [Abstract] - Antonín Holý, Jitka Kohoutová, Aleš Merta and Ivan Votruba
9-(Aminoalkyl)-8-hydroxyadenines: Preparation, mechanism of formation and use in affinity chromatography of S-adenosyl-L-homocysteine hydrolase
1986, Vol. 51, Issue 2, pp. 459–477 [Abstract] - Antonín Holý, Anita Ludziša, Ivan Votruba, Kateřina Šedivá and Helmut Pischel
Preparation of analogues of cytosine and 2-pyrimidinone nucleosides and their effect on bacterial (Escherichia coli A 19) cytidine aminohydrolase
1985, Vol. 50, Issue 2, pp. 393–417 [Abstract] - Antonín Holý, Ivan Votruba and Erik De Clercq
Structure-activity studies on open-chain analogues of nucleosides: Inhibition of S-adenosyl-L-homocysteine hydrolase and antiviral activity 2. Acid open-chain analogues
1985, Vol. 50, Issue 1, pp. 262–279 [Abstract] - Antonín Holý, Ivan Votruba and Erik De Clercq
Structure-activity studies on open-chain analogues of nucleosides: Inhibition of S-adenosyl-L-homocysteine hydrolase and antiviral activity 1. Neutral open-chain analogues
1985, Vol. 50, Issue 1, pp. 245–261 [Abstract] - Ladislava Šebestová, Ivan Votruba and Antonín Holý
S-adenosine-L-homocysteine hydrolase from Nicotiana tabacum L.: Isolation and properties
1984, Vol. 49, Issue 6, pp. 1543–1551 [Abstract] - Aleš Merta, Ivan Votruba, Jiří Veselý and Antonín Holý
S-adenosyl-L-homocysteine hydrolase from mouse leukemic cells: Isolation and properties
1983, Vol. 48, Issue 9, pp. 2701–2708 [Abstract] - Ivan Votruba, Antonín Holý and Ivan Rosenberg
Affinity chromatography of rat liver S-adenosyl-L-homocysteine hydrolase
1983, Vol. 48, Issue 9, pp. 2549–2557 [Abstract] - Antonín Holý, Ivan Votruba and Erik De Clercq
Synthesis and antiviral activity of stereoisomeric eritadenines
1982, Vol. 47, Issue 5, pp. 1392–1407 [Abstract] - Ivan Votruba and Antonín Holý
Eritadenines - Novel type of potent inhibitors of S-adenosyl-L-homocysteine hydrolase
1982, Vol. 47, Issue 1, pp. 167–172 [Abstract] - Ivan Votruba and Antonín Holý
Inhibition of S-adenosyl-L-homocysteine hydrolase by the aliphatic nucleoside analogue - 9-(S)-(2,3-dihydroxypropyl)adenine
1980, Vol. 45, Issue 11, pp. 3039–3044 [Abstract]
