Collect. Czech. Chem. Commun. 2006, 71, 679-690
https://doi.org/10.1135/cccc20060679

A Study of 5-Nitroindole Alkylation

Václav Kozmíka, Bedřich Košataa, Jiří Svobodaa,* and Miroslav Kuchařb

a Department of Organic Chemistry, Institute of Chemical Technology, Prague, 166 28 Prague 6, Czech Republic
b Zentiva, 102 01 Prague 10, Czech Republic

Individual author index pages


Other CCCC articles of these authors

  • Aleš Machara, Václav Kozmík, Michaela Pojarová, Hana Dvořáková and Jiří Svoboda*
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    2009, Vol. 74, Issue 5, pp. 785–798 [Abstract]
  • Aleš Machara, Michaela Pojarová and Jiří Svoboda*
    Synthesis and Cycloaddition Reaction of 3-Vinylthieno[3,2-b][1]benzothiophene
    2007, Vol. 72, Issue 7, pp. 952–964 [Abstract]
  • Miroslav Kuchař*, Bohumila Brunová, Richard Junek, Robert Rodling, Josef Hájíček, Vladimíra Panajotová and Antonín Jandera
    The Antileukotrienic Derivatives and Homologues of [(Quinolin-2-ylmethoxy)sulfanyl]benzoic Acids with Reduced Lipophilicity
    2005, Vol. 70, Issue 9, pp. 1357–1371 [Abstract]
  • Miroslav Kuchař*, Vojtěch Kmoníček, Vladimíra Panajotová, Antonín Jandera, Bohumila Brunová, Richard Junek, Věra Bucharová, Jan Čejka and Dalibor Šatinský
    Derivatives of (Phenylsulfanyl)benzoic Acids with Multiple Antileukotrienic Activity
    2004, Vol. 69, Issue 11, pp. 2098–2120 [Abstract]
  • Vladimír Wsól*, Barbora Szotáková, Vendula Baliharová, Luděk Šišpera, Michal Holčapek, Lenka Kolářová, Bohumila Suchanová, Miroslav Kuchař and Lenka Skálová
    The Phase I Biotransformation of the Potential Antileukotrienic Drug Quinlukast in Rat Microsomes and Hepatocytes
    2004, Vol. 69, Issue 3, pp. 689–702 [Abstract]
  • Michal Rejňák, Jiří Klíma, Jiří Svoboda and Jiří Ludvík*
    Synthesis and Electrochemical Reduction of Methyl 3-Halo-1-benzothiophene-2-carboxylates
    2004, Vol. 69, Issue 1, pp. 242–260 [Abstract]
  • Marie Mézlová, Hana Petříčková, Petr Maloň, Václav Kozmík and Jiří Svoboda*
    Axially Chiral 3,3'-Bi(1-benzothiophene)-2,2'-dicarboxylic Acid and Its Derivatives
    2003, Vol. 68, Issue 5, pp. 1020–1038 [Abstract]
  • Bedřich Košata, Václav Kozmík and Jiří Svoboda*
    Reactivity of [1]Benzothieno[3,2-b][1]benzothiophene - Electrophilic and Metallation Reactions
    2002, Vol. 67, Issue 5, pp. 645–664 [Abstract]
  • Kateřina Černovská, Miloslav Nič, Pavel Pihera and Jiří Svoboda*
    A Novel Synthesis of [1]Benzothieno[3,2-b][1]benzofuran
    2000, Vol. 65, Issue 12, pp. 1939–1949 [Abstract]
  • Jiří Svoboda*, Michal Štádler, Antonín Jandera, Vladimíra Panajotová and Miroslav Kuchař
    Synthesis and Biological Evaluation of New Antiinflammatory 1-Benzothiophene-2-carboxanilides
    2000, Vol. 65, Issue 7, pp. 1082–1092 [Abstract]
  • Pavel Pihera and Jiří Svoboda*
    Reactivity Studies of [1]Benzothieno[3,2-b][1]benzofuran
    2000, Vol. 65, Issue 1, pp. 58–76 [Abstract]
  • Pavel Pihera, Hana Dvořáková and Jiří Svoboda*
    Diels-Alder Reactions of Vinyl Derivatives of [1]Benzothieno[3,2-b]furan
    1999, Vol. 64, Issue 2, pp. 389–407 [Abstract]
  • Václav Kozmík, Pavel Lhoták, Želmíra Odlerová and Jaroslav Paleček
    Azachalcone Derivatives and Their Bis Substituted Analogs as Novel Antimycobacterial Agents
    1998, Vol. 63, Issue 5, pp. 698–712 [Abstract]
  • Pavel Pihera, Jaroslav Paleček and Jiří Svoboda
    Diels-Alder Reactions of [1]Benzothieno[3,2-b]furan
    1998, Vol. 63, Issue 5, pp. 681–697 [Abstract]
  • Miroslav Kuchař, Kateřina Čulíková, Vladimíra Panajotovová, Bohumila Brunová, Antonín Jandera and Vojtěch Kmoníček
    2,4-Dihydroxyacetophenone Derivatives as Antileukotrienics with a Multiple Activity Mechanism
    1998, Vol. 63, Issue 1, pp. 103–114 [Abstract]
  • Petr Váchal, Pavel Pihera and Jiří Svoboda
    Thieno[3,2-b]benzofuran - Synthesis and Reactions
    1997, Vol. 62, Issue 9, pp. 1468–1480 [Abstract]
  • Miroslav Terinek, Václav Kozmík and Jaroslav Paleček
    Prostanoids: Synthesis of Enantiomers of 15-Deoxy-16-hydroxy-16-methylprostaglandin E1
    1997, Vol. 62, Issue 8, pp. 1325–1341 [Abstract]
  • Miroslav Kuchař, Marie Poppová, Antonín Jandera, Vladimíra Panajotovová, Hana Zůnová, Miloš Buděšínský, Hana Tomková, Alexandr Jegorov and Jan Taimr
    Chiral Forms of 4-(2',4'-Difluorobiphenyl-4-yl)-2-methyl-4-oxobutanoic Acid (Flobufen) and Its Metabolite.Synthesis and Basic Biological Properties
    1997, Vol. 62, Issue 3, pp. 498–509 [Abstract]
  • Jiří Svoboda, Václav Kozmík, Ivan Veselý and Jaroslav Paleček
    New Synthesis of Important Prostanoid Intermediate
    1996, Vol. 61, Issue 10, pp. 1509–1519 [Abstract]
  • Jiří Svoboda, Pavel Pihera, Petr Sedmera and Jaroslav Paleček
    Electrophilic Substitution Reactions of [1]Benzothieno[3,2-b]furan
    1996, Vol. 61, Issue 6, pp. 888–900 [Abstract]
  • Jiří Svoboda and Jaroslav Paleček
    New Method for Preparation of 1-Azabicyclo[2.2.2]octane-4-carbonitrile and 1-Azabicyclo[3.2.2]nonane-5-carbonitrile
    1995, Vol. 60, Issue 9, pp. 1536–1540 [Abstract]
  • Miroslav Kuchař, Václav Vosátka, Marie Poppová, Eva Knězová, Vladimíra Panajotovová, Hana Tomková and Jan Taimr
    Some Analogs of 4-(2',4'-Difluorobiphenyl-4-yl)-2-methyl-4-oxobutanoic Acid: Synthesis and Antiinflammatory Activity
    1995, Vol. 60, Issue 6, pp. 1026–1033 [Abstract]
  • Miroslav Kuchař, Marie Poppová, Hana Zůnová, Eva Knězová, Václav Vosátka and Marek Příhoda
    4-(2',4'-Difluorobiphenyl-4-yl)-2-methyl-4-oxobutanoic Acid and Its Derivatives
    1994, Vol. 59, Issue 12, pp. 2705–2713 [Abstract]
  • Václav Kozmík and Jaroslav Paleček
    Synthetic Analogues of 15,15-Acetals of Prostaglandin F2α and E2
    1994, Vol. 59, Issue 11, pp. 2533–2544 [Abstract]
  • Václav Kozmík and Jaroslav Paleček
    Synthetic Analogues of Prostaglandins F2α and E2
    1994, Vol. 59, Issue 1, pp. 138–148 [Abstract]
  • Jiří Svoboda, Miloslav Nič and Jaroslav Paleček
    Synthesis of [1]Benzothieno[3,2-b]furan - A New Fused Benzoheterocyclic System
    1993, Vol. 58, Issue 12, pp. 2983–2986 [Abstract]
  • Jiří Svoboda, Miloslav Nič and Jaroslav Paleček
    Application of Magnesium Alkoxides to Syntheses of Benzoheterocyclic Compounds
    1993, Vol. 58, Issue 3, pp. 592–599 [Abstract]
  • Václav Kozmík and Jaroslav Paleček
    Simple Preparation of Methyl 4-Chloromethyl- and Methyl 5-Chloromethyl-2-thiophenecarboxylate
    1992, Vol. 57, Issue 7, pp. 1483–1486 [Abstract]
  • Jiří Svoboda, Miloslav Nič and Jaroslav Paleček
    An Anomalous Course of the Darzens Reaction Catalyzed with Magnesium Methoxide
    1992, Vol. 57, Issue 1, pp. 119–122 [Abstract]
  • Jiří Svoboda and Jaroslav Paleček
    Synthesis of N-[(3-substituted phenoxy)alkyl]acetohydroxamic acids, potential inhibitors of the enzyme 5-lipoxygenase
    1991, Vol. 56, Issue 6, pp. 1317–1332 [Abstract]
  • Bohdan Schneider, Václav Rejholec and Miroslav Kuchař
    Three-dimensional structures of substituted diphenyl sulfides
    1990, Vol. 55, Issue 11, pp. 2590–2601 [Abstract]
  • Miloš Beran, Antonín Černý, Miroslav Kuchař, Hana Adamírová, Jiří Holubek, Jan Taimr, Jaroslav Vachek, Maria Frühaufová, Karel Řežábek, Martin Valchář and Ivan Krejčí
    9,10-Dihydroergopeptines modified in position 6
    1990, Vol. 55, Issue 3, pp. 819–832 [Abstract]
  • Miroslav Kuchař, Jaroslava Grimová, Václav Rejholec, Hana Tomková, Magda Jelínková and Jiří Holubek
    Use of QSAR in design of antiinflammatory fluorinated arylalkanoic acids
    1990, Vol. 55, Issue 1, pp. 296–306 [Abstract]
  • Ivan Veselý, Václav Kozmík, Václav Dědek, Jaroslav Paleček, Jiří Mostecký and Ivan Stibor
    Large-scale synthesis of racemic “Corey lactone”
    1989, Vol. 54, Issue 6, pp. 1683–1686 [Abstract]
  • Miroslav Kuchař, Eva Maturová, Bohumila Brunová, Jaroslava Grimová, Hana Tomková and Jiří Holubek
    Quantitative relations between structure and antiinflammatory activity of aryloxoalkanoic acids
    1988, Vol. 53, Issue 8, pp. 1862–1872 [Abstract]
  • Jiří Svoboda, Zuzana Kocfeldová and Jaroslav Paleček
    Reaction of 4-substituted benzaldehydes and acetophenones with chloroacetonitrile
    1988, Vol. 53, Issue 4, pp. 822–832 [Abstract]
  • Jiří Svoboda, Karel Čapek and Jaroslav Paleček
    Esters of arylpropionic acids with 1,2:5,6-di-O-isopropylidene- and 1,2-O-isopropylidene-α-D-glucofuranose
    1987, Vol. 52, Issue 3, pp. 766–774 [Abstract]
  • Miroslav Kuchař, Bohumila Brunová, Jaroslava Grimová, Stanislav Vaněček and Jiří Holubek
    Synthesis of cyclohexylaliphatic acids and their pharmacological properties
    1986, Vol. 51, Issue 12, pp. 2896–2908 [Abstract]
  • Miroslav Kuchař, Bohumila Brunová, Jaroslava Grimová, Václav Rejholec and Václav Čepelák
    On the quantitative relations between structure and antiaggregation activity of ω-aryl-ω-oxoalkanoic acids
    1986, Vol. 51, Issue 11, pp. 2617–2625 [Abstract]
  • Jiří Svoboda, Jaroslav Paleček and Václav Dědek
    Phase transfer catalysed N-substitution of 2H-1,2-benzisothiazolin-3-one 1,1-dioxide
    1986, Vol. 51, Issue 6, pp. 1304–1310 [Abstract]
  • Jiří Svoboda, Jaroslav Paleček and Václav Dědek
    The synthesis of substituted 2H-1,2-benzothiazines 1,1-dioxides
    1986, Vol. 51, Issue 5, pp. 1133–1139 [Abstract]
  • Jiří Svoboda, Jaroslav Paleček, Václav Dědek and Jiří Mostecký
    One-step synthesis of substituted 2-aryl-2-bromoalkyl-1,3-dioxolanes
    1984, Vol. 49, Issue 6, pp. 1515–1520 [Abstract]
  • Miroslav Kuchař, Bohumila Brunová, Václav Rejholc, Magda Jelínková, Jiří Holubek and Oldřich Němeček
    Quantitative relations between structure and activation of fibrinolysis in selected series of arylaliphatic acids
    1984, Vol. 49, Issue 1, pp. 122–136 [Abstract]
  • Miroslav Kuchař, Václav Rejholec, Zdeněk Roubal and Oluše Matoušová
    The effects of lipophilicity on the inhibition of denaturation of serum albumin and on the activation of fibrinolysis observed with a series of benzyloxyarylaliphatic acids
    1983, Vol. 48, Issue 4, pp. 1077–1088 [Abstract]
  • Jiří Svoboda, Oldřich Paleta and Václav Dědek
    Synthetic transformations of dimethyl perfluoro-4-methyl-2-pentenedioate
    1982, Vol. 47, Issue 12, pp. 3418–3423 [Abstract]
  • Miroslav Kuchař, Václav Rejholec, Bohumila Brunová, Jaroslava Grimová, Oluše Matoušová, Oldřich Němeček and Hana Čepeláková
    Benzyloxyarylaliphatic acids: Synthesis and quantitative relations between structure and antiinflammatory activity
    1982, Vol. 47, Issue 9, pp. 2514–2524 [Abstract]
  • Oldřich Paleta, Jiří Svoboda and Václav Dědek
    Anionic cis-trans isomerization of dialkyl perfluoro(4-methyl-2-pentene)dioates. A non-classical equilibrium dependence
    1982, Vol. 47, Issue 1, pp. 54–58 [Abstract]
  • Jiří Svoboda, Oldřich Paleta and Václav Dědek
    Derivatives of 2,3-difluoro-2-butenedioic acid and their isomerization reactions
    1981, Vol. 46, Issue 6, pp. 1495–1503 [Abstract]
  • Jiří Svoboda, Oldřich Paleta, František Liška and Václav Dědek
    Fluorinated 3-diethylaminopropenoates and their reactions
    1981, Vol. 46, Issue 6, pp. 1389–1396 [Abstract]
  • Jiří Svoboda, Oldřich Paleta and Václav Dědek
    Reaction of chlorodifluoropropenoates with potassium fluoride
    1981, Vol. 46, Issue 5, pp. 1272–1279 [Abstract]
  • Miroslav Kuchař, Bohumila Brunová, Václav Rejholec, Zdeněk Roubal and Oldřich Němeček
    The synthesis of arylpropionic acids and the quantitative relationship between the structure and the activation of fibrinolysis
    1981, Vol. 46, Issue 5, pp. 1173–1187 [Abstract]
  • Oldřich Paleta, Jiří Svoboda, Václav Havlů and Václav Dědek
    Anionic cis-trans isomerisation of dimethyl perfluoro-(4-methyl-2-pentene)dioate
    1980, Vol. 45, Issue 12, pp. 3360–3369 [Abstract]
  • Miroslav Kuchař, Bohumila Brunová, Zdeněk Roubal, Jiří Schlanger and Oldřich Němeček
    Synthesis of arylacetic acids and their effect on activation of fibrinolysis. Quantitative relations between structure and biological activity
    1980, Vol. 45, Issue 5, pp. 1401–1409 [Abstract]
  • Jiří Svoboda, Oldřich Paleta and Václav Dědek
    Ionic dimerisation of trifluoropropenenitrile and its addition reactions with methyl trifluoropropenoate
    1980, Vol. 45, Issue 2, pp. 406–414 [Abstract]
  • Miroslav Kuchař, Václav Rejholec, Zdeněk Roubal and Oldřich Němeček
    Quantitative relationships between structure and fibrinolytic activity in the series of α-methyl-β-arylpropionic acids
    1979, Vol. 44, Issue 1, pp. 183–193 [Abstract]
  • Oldřich Paleta, Jiří Svoboda and Václav Dědek
    UV-light induced cycloaddition of 3,4-dichloro-3,4,4-trifluoro-2-butanone to 2-methyl-2-butene
    1978, Vol. 43, Issue 11, pp. 2932–2941 [Abstract]