Collect. Czech. Chem. Commun.
2006, 71, 1169-1185
https://doi.org/10.1135/cccc20061169
The Effect of pH on Peroxidase-Mediated Oxidation of and DNA Adduct Formation by Ellipticine
Jitka Poljakováa, Martin Dračínskýa, Eva Freib, Jiří Hudečeka and Marie Stiborováa,*
a Department of Biochemistry, Faculty of Science, Charles University, Albertov 2030, 128 40 Prague 2, Czech Republic
b Division of Molecular Toxicology, German Cancer Research Center, In Neuenheimer Feld 280, 69120 Heidelberg, Germany
Individual author index pages
Other CCCC articles of these authors
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Nucleosides and nucleotides containing 8-aza-7,9-dideazaxanthine
Symposium Series 2008, Vol. 10, pp. 426–428 [Abstract]
Published online 2015-10-30 18:44:11 - Petr Jansa, Martin Dračínský and Antonín Holý
Efficient synthesis of "open-ring, close-ring" acyclic nucleoside phosphonates
Symposium Series 2008, Vol. 10, pp. 360–361 [Abstract]
Published online 2015-10-30 18:42:02 - Martin Dračínský, Marcela Krečmerová and Antonín Holý
Study of chemical stability of antivirally active 5-azacytosine acyclic nucleoside phosphonates using NMR spectroscopy
Symposium Series 2008, Vol. 10, pp. 338–340 [Abstract]
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Synthesis of acyclic nucleoside diphosphate mimics
Symposium Series 2008, Vol. 10, pp. 336–337 [Abstract]
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Synthesis of N9-(3-fluoro-2-phosphonomethoxypropyl) (FPMP) derivatives of N6-substituted adenines and 2,6-diaminopurines
Symposium Series 2008, Vol. 10, pp. 315–316 [Abstract]
Published online 2015-10-30 18:40:22 - Radim Nencka, Hubert Hřebabecký, Ivan Votruba, Martin Dračínský and Antonín Holý
Metalation of 6-halo-2,4-dimethoxypyrimidines as the key step for the synthesis of biologicaly active compounds
Symposium Series 2008, Vol. 10, pp. 249–253 [Abstract]
Published online 2015-10-30 18:38:37 - Tomáš Tichý, Graciela Andrei, Martin Dračínský, Antonín Holý, Jan Balzarini, Robert Snoeck and Marcela Krečmerová
New amphiphilic prodrugs of adefovir and cidofovir
Symposium Series 2011, Vol. 12, pp. 477–479 [Abstract]
Published online 2015-08-20 10:25:04 - David Mařák, Miroslav Otmar, Martin Dračínský and Marcela Krečmerová
Nucleosides containing 8-aza-7,9-dideazaxanthine
Symposium Series 2011, Vol. 12, pp. 383–385 [Abstract]
Published online 2015-08-20 10:19:50 - Marcela Krečmerová, Antonín Holý, Dana Hocková, Martin Dračínský, Dianne T. Keough and Luke W. Guddat
9-[2-Hydroxy-3-(phosphonomethoxy)propyl] ("iso-HPMP") derivatives of purine bases and their side-chain modified analogues: synthesis and antimalarial activity
Symposium Series 2011, Vol. 12, pp. 381–382 [Abstract]
Published online 2015-08-20 10:19:45 - Soňa Kovačková, Martin Dračínský and Dominik Rejman
Piperidine nucleoside phosphonic acid derivatives
Symposium Series 2011, Vol. 12, pp. 372–374 [Abstract]
Published online 2015-08-20 10:19:28 - Petr Jansa, Antonín Holý, Martin Dračínský, Ondřej Baszczyňski, Michal Česnek and Zlatko Janeba
The unique impact of microwave irradiaton on the chemistry of acyclic nucleoside phosphonates
Symposium Series 2011, Vol. 12, pp. 347–348 [Abstract]
Published online 2015-08-20 10:18:28 - Martin Dračínský, Petr Jansa, Jana Chocholoušová, Jaroslav Vacek, Soňa Kovačková and Antonín Holý
The mechanism of isotopic exchange reaction of hydrogen H-5 of uracil derivatives in water and in non-protic solvents
Symposium Series 2011, Vol. 12, pp. 323–324 [Abstract]
Published online 2015-08-20 10:12:29 - Lucie Čechová, Petr Jansa, Michal Šála, Martin Dračínský, Antonín Holý and Zlatko Janeba
The optimized microwave-assisted decomposition of formamides and its synthetic utility in the amination of purines and pyrimidines
Symposium Series 2011, Vol. 12, pp. 312–313 [Abstract]
Published online 2015-08-20 10:12:06 - Michal Česnek, Petra Břehová, Martin Dračínský, Antonín Holý and Zlatko Janeba
The efficient synthesis of 2-aryl substituted pyrimidine acyclic nucleoside phosphonates using Liebeskind-Srogl cross-coupling
Symposium Series 2011, Vol. 12, pp. 310–311 [Abstract]
Published online 2015-08-20 10:12:01 - Ondřej Baszczyňski, Petr Jansa, Dana Hocková, Zlatko Janeba, Martin Dračínský, Antonín Holý, Dianne T. Keough, John de Jersey and Luke W. Guddat
3-Fluoro-2-(phosphonomethoxy)propyl hypoxanthine and guanine derivatives as inhibitors of plasmodial hypoxanthine-guanine-xanthine phosphoribosyltransferases
Symposium Series 2011, Vol. 12, pp. 302–303 [Abstract]
Published online 2015-08-20 10:11:43 - Milan Dejmek, Hubert Hřebabecký, Michal Šála, Martin Dračínský and Radim Nencka
Synthesis of conformationally locked carbocyclic nucleosides with norbornane as pseudosugar moiety
Symposium Series 2011, Vol. 12, pp. 208–212 [Abstract]
Published online 2015-08-20 10:01:05 - Michal Šála, Milan Dejmek, Eliška Procházková, Hubert Hřebabecký, Jiří Rybáček, Martin Dračínský, Pavel Novák, Šárka Rosenbergová, Jiří Fukal, Vladimír Sychrovský, Ivan Rosenberg and Radim Nencka
Novel conformationally locked nucleosides and oligonucleotides based on bicyclo[3.2.1]octane scaffold as a pseudosugar moiety
Symposium Series 2014, Vol. 14, pp. 379–380 [Abstract]
Published online 2015-07-06 23:09:07 - Eliška Procházková, Hubert Hřebabecký, Radim Nencka and Martin Dračínský
Enzymatic decomposition of a locked nucleoside phosphoramidate monitored by 31P NMR spectroscopy
Symposium Series 2014, Vol. 14, pp. 356–357 [Abstract]
Published online 2015-07-06 23:08:13 - Zlatko Janeba, Lucie Čechová, Jiří Žurek, Eliška Procházková and Martin Dračínský
Synthesis and biological properties of polysubstituted 5-nitrosopyrimidines
Symposium Series 2014, Vol. 14, pp. 285–286 [Abstract]
Published online 2015-07-06 23:05:07 - Eliška Procházková, Lucie Čechová, Jiří Žurek, Zlatko Janeba and Martin Dračínský
Switchable intramolecular hydrogen bond in polysubstituted 5-nitrosopyrimidines
Symposium Series 2014, Vol. 14, pp. 251–254 [Abstract]
Published online 2015-07-06 23:03:40 - Martin Dračínský*, Petr Jansa* and Tomáš Elbert
Isotope exchange reactions of the hydrogen H-5 of selected pyrimidine derivatives and the preparation of tritium-labeled pyrimidines
2011, Vol. 76, Issue 12, pp. 1567–1577 [Abstract] - Milan Dejmek, Hubert Hřebabecký, Martin Dračínský, Johan Neyts, Pieter Leyssen, Helena Mertlíková-Kaiserová and Radim Nencka*
Conformationally locked nucleoside analogues based on the bridgehead substituted 7-oxonorbornane and their antiviral properties
2011, Vol. 76, Issue 12, pp. 1549–1566 [Abstract] - Petr Jansa*, Viktor Kolman, Alexandra Kostinová, Martin Dračínský, Helena Mertlíková-Kaiserová and Zlatko Janeba
Efficient synthesis and biological properties of the 2′-trifluoromethyl analogues of acyclic nucleosides and acyclic nucleoside phosphonates
2011, Vol. 76, Issue 10, pp. 1187–1198 [Abstract] - Petr Jansa*, Petr Špaček, Ivan Votruba, Petra Břehová, Martin Dračínský, Blanka Klepetářová and Zlatko Janeba
Efficient one-pot synthesis of polysubstituted 6-[(1H-1,2,3-triazol-1-yl)methyl]uracils through the “click” protocol
2011, Vol. 76, Issue 9, pp. 1121–1131 [Abstract] - Radim Nencka, Hubert Hřebabecký* and Martin Dračínský
Model synthesis of six-membered carbocyclic spironucleosides
2010, Vol. 75, Issue 12, pp. 1259–1272 [Abstract] - Karel Naiman, Petr Hodek, Jiří Liberda, Heinz H. Schmeiser, Eva Frei and Marie Stiborová*
Rat liver microsomal metabolism of o-aminophenol and N-(2-methoxyphenyl)hydroxylamine, two metabolites of the environmental pollutant and carcinogen o-anisidine in humans
2010, Vol. 75, Issue 12, pp. 1229–1247 [Abstract] - Martina Svobodová, Markéta Martínková, Eva Frei and Marie Stiborová*
Identification of human enzymes oxidizing a human metabolite of carcinogenic 2-nitroanisole, 2-nitrophenol. Evidence for its oxidative detoxification by human cytochromes P450
2010, Vol. 75, Issue 6, pp. 703–719 [Abstract] - Lucie Bořek-Dohalská and Marie Stiborová*
Cytochrome P450 3A activities and their modulation by α-naphthoflavone in vitro are dictated by the efficiencies of model experimental systems
2010, Vol. 75, Issue 2, pp. 201–220 [Abstract] - Michal Šála, Hubert Hřebabecký*, Martin Dračínský, Milena Masojídková, Armando M. De Palma, Johan Neyts and Antonín Holý
Synthesis of novel racemic carbocyclic nucleosides derived from 5,6-disubstituted norbornene
2010, Vol. 75, Issue 1, pp. 1–20 [Abstract] - Hubert Hřebabecký*, Martin Dračínský and Antonín Holý
New carbocyclic nucleoside analogues built on a bicyclo[2.2.2]octane-2,2-dimethanol template
2009, Vol. 74, Issue 9, pp. 1425–1441 [Abstract] - Hubert Hřebabecký*, Martin Dračínský, Armando M. De Palma, Johan Neyts and Antonín Holý
Synthesis of novel carbocyclic nucleoside analogues derived from 7-oxabicyclo[2.2.1]heptane-2-methanol
2009, Vol. 74, Issue 3, pp. 487–502 [Abstract] - Hubert Hřebabecký*, Martin Dračínský, Armando M. De Palma, Johan Neyts and Antonín Holý
Synthesis of novel racemic carbocyclic nucleoside analogues derived from 4,8-dioxatricyclo[4.2.1.03,7]nonane-9-methanol and 4-oxatricyclo[4.3.1.03,7]decane-10-methanol, compounds with activity against Coxsackie viruses
2009, Vol. 74, Issue 3, pp. 469–485 [Abstract] - Hubert Hřebabecký*, Martin Dračínský and Antonín Holý
Synthesis of Novel Carbocyclic Nucleoside Analogues Containing Bicyclo[2.2.1]hept-2-ene-2-methanol
2008, Vol. 73, Issue 1, pp. 44–58 [Abstract] - Milan Dejmek, Hubert Hřebabecký*, Martin Dračínský and Antonín Holý
Synthesis of Novel Carbocyclic Nucleoside Analogues Derived from 2-(Hydroxymethyl)bicyclo[2.2.1]heptane
2007, Vol. 72, Issue 11, pp. 1523–1544 [Abstract] - Marie Stiborová*, Helena Dračínská, Dagmar Aimová, Petr Hodek, Jiří Hudeček, Helena Ryšlavá, Heinz H. Schmeiser and Eva Frei
The Anticancer Drug Ellipticine is an Inducer of Rat NAD(P)H:Quinone Oxidoreductase
2007, Vol. 72, Issue 10, pp. 1350–1364 [Abstract] - Hubert Hřebabecký*, Martin Dračínský and Antonín Holý
Synthesis of Novel Carbocyclic Nucleosides and Pro-Tides Derived from 4-Oxatricyclo[4.2.1.03,7]nonane-9-methanol
2007, Vol. 72, Issue 10, pp. 1331–1349 [Abstract] - Silvie Vrbková*, Martin Dračínský and Antonín Holý
Bifunctional Acyclic Nucleoside Phosphonates: 2. Symmetrical 2-{[Bis(phosphono)methoxy]methyl}ethyl Derivatives of Purines and Pyrimidines
2007, Vol. 72, Issue 7, pp. 965–983 [Abstract] - Martina Džoganová, Miloslav Černý, Miloš Buděšínský*, Martin Dračínský and Tomáš Trnka
Epoxide Migration and Pseudo-Epoxide Migration of 1,6:2,3- and 1,6:3,4-Dianhydro-β-D-hexopyranoses. Synthesis of Some Deoxy Halo Derivatives of 1,6-Anhydro-β-D-hexopyranoses
2006, Vol. 71, Issue 10, pp. 1497–1515 [Abstract] - Martin Dračínský, Simona Hybelbauerová, Jan Sejbal and Miloš Buděšínský*
Preparation and Conformational Study of B-Ring Substituted Lupane Derivatives
2006, Vol. 71, Issue 8, pp. 1131–1160 [Abstract] - Hubert Hřebabecký*, Milena Masojídková, Martin Dračínský and Antonín Holý
Synthesis of Novel Conformationally Locked Carbocyclic Nucleosides Derived from 3-(Hydroxymethyl)bicyclo[2.2.1]heptane-2,5-diol
2006, Vol. 71, Issue 6, pp. 871–888 [Abstract] - Martin Dračínský, Václav Richtr, Václav Křeček, Jan Sejbal, Jiří Klinot and Miloš Buděšínský*
Preparation and Conformational Study of 19β,28-Epoxy-18α-olean-5-ene Derivatives
2006, Vol. 71, Issue 3, pp. 387–410 [Abstract] - Petr Hodek*, Tomáš Koblas, Helena Rýdlová, Božena Kubíčková, Miroslav Šulc, Jiří Hudeček and Marie Stiborová
Chicken Egg Yolk as an Excellent Source of Highly Specific Antibodies Against Cytochromes P450
2004, Vol. 69, Issue 3, pp. 659–673 [Abstract] - Lucie Bořek-Dohalská, Eva Frei and Marie Stiborová*
DNA Adduct Formation by the Anticancer Drug Ellipticine and Its Hydroxy Derivatives in Human Breast Adenocarcinoma MCF-7 Cells
2004, Vol. 69, Issue 3, pp. 603–615 [Abstract] - Markéta Mikšanová, Petr Novák, Eva Frei and Marie Stiborová*
Metabolism of Carcinogenic 2-Nitroanisole in Rat, Rabbit, Porcine and Human Hepatic Cytosol
2004, Vol. 69, Issue 3, pp. 589–602 [Abstract] - Marie Stiborová*, Martina Rupertová, Petr Hodek, Eva Frei and Heinz H. Schmeiser
Monitoring of DNA Adducts in Humans and 32P-Postlabelling Methods. A Review
2004, Vol. 69, Issue 3, pp. 476–498 [Abstract] - Václav Martínek and Marie Stiborová*
Metabolism of Carcinogenic Azo Dye Sudan I by Rat, Rabbit, Minipig and Human Hepatic Microsomes
2002, Vol. 67, Issue 12, pp. 1883–1898 [Abstract] - Marie Stiborová*, Miroslav Hájek, Hana Vošmiková, Eva Frei and Heinz H. Schmeiser
Isolation of DT-Diaphorase [NAD(P)H Dehydrogenase (Quinone)] from Rat Liver Cytosol: Identification of New Enzyme Substrates, Carcinogenic Aristolochic Acids
2001, Vol. 66, Issue 6, pp. 959–972 [Abstract] - Martin Beneš, Jiří Hudeček, Pavel Anzenbacher and Martin Hof*
Coumarin 6, Hypericin, Resorufins, and Flavins: Suitable Chromophores for Fluorescence Correlation Spectroscopy of Biological Molecules
2001, Vol. 66, Issue 6, pp. 855–869 [Abstract] - Markéta Mikšanová, Jiří Hudeček, Jan Páca and Marie Stiborová*
To the Mechanism of Horseradish Peroxidase-Mediated Degradation of a Recalcitrant Dye Remazol Brilliant Blue R
2001, Vol. 66, Issue 4, pp. 663–675 [Abstract] - Marie Stiborová*, Markéta Mikšanová, Václav Martínek and Eva Frei
Heme Peroxidases: Structure, Function, Mechanism and Involvement in Activation of Carcinogens. A Review
2000, Vol. 65, Issue 3, pp. 297–325 [Abstract] - Lucie Bořek-Dohalská*, Petr Hodek and Marie Stiborová
New Selective Inhibitors of Cytochrome P450 2B4 and an Activator of Cytochrome P450 3A6 in Rabbit Liver Microsomes
2000, Vol. 65, Issue 1, pp. 122–132 [Abstract] - Marie Stiborová*, Heinz H. Schmeiser, Andrea Breuer and Eva Frei
32P-Postlabelling Analysis of DNA Adducts with 1-(Phenylazo)-2-naphthol (Sudan I, Solvent Yellow 14) Formed in vivo in Fisher 344 Rats
1999, Vol. 64, Issue 8, pp. 1335–1347 [Abstract] - Pavel Anzenbacher, Jiří Hudeček, Reinhard Lange and Frédéric Bancel
Accessibility of Tyrosine Residues in Cytochrome P-450scc (CYP11A1)
1998, Vol. 63, Issue 10, pp. 1678–1682 [Abstract] - Marie Stiborová, Heinz H. Schmeiser and Eva Frei
To the Mechanism of 2-Nitroanisole Carcinogenicity: in vitro Metabolism of 2-Nitroanisole Mediated by Peroxidasesand Xanthine Oxidase
1998, Vol. 63, Issue 6, pp. 857–869 [Abstract] - Pavel Anzenbacher, Nicole Bec, Jiří Hudeček, Reinhard Lange and Eva Anzenbacherová
High Conformational Stability of Cytochrome P-450 1A2. Evidence from UV Absorption Spectra
1998, Vol. 63, Issue 3, pp. 441–448 [Abstract] - Marie Stiborová and Hana Hansíková
Peroxidases from Tulip Bulbs (Tulipa fosteriana, L.) Oxidize Xenobiotics NNitrosodimethylamine and N-Nitroso-N-methylaniline in vitro
1997, Vol. 62, Issue 11, pp. 1804–1814 [Abstract] - Marie Stiborová, Eva Frei and Heinz H. Schmeiser
Study on N-Demethylation of N,N-Dimethyl-4-aminoazobenzene and N-Nitrosamines by Prostaglandin H Synthase
1997, Vol. 62, Issue 6, pp. 971–980 [Abstract] - Marie Stiborová and Hana Hansíková
Cytochrome P-450 from Tulip Bulbs (Tulipa fosteriana L.) Oxidizes an Azo Dye Sudan I (1-Phenylazo-2-hydroxynaphthalene, Solvent Yellow 14) in vitro
1996, Vol. 61, Issue 11, pp. 1689–1696 [Abstract] - Marie Stiborová, Befekadu Asfaw, Eva Frei and Heinz H. Schmeiser
Oxidation of Azo Dyes by Peroxidase: Additional Evidence of a One-Electron Mechanism of Oxidation of Dimethylaminoazobenzene and Sudan I (Solvent Yellow 14)
1996, Vol. 61, Issue 6, pp. 962–972 [Abstract] - Marie Stiborová, Eva Frei, Heinz H. Schmeiser and Manfred Wiessler
Cytochrome P-450 and Peroxidase Oxidize Detoxication Products of Carcinogenic Aristolochic Acids (Aristolactams) to Reactive Metabolites Binding to DNA in vitro
1995, Vol. 60, Issue 12, pp. 2189–2199 [Abstract] - Marie Stiborová, Befekadu Asfaw, Eva Frei, Heinz H. Schmeiser and Manfred Wiessler
Identification of 1-(3,4-Dihydroxyphenylazo)-2-hydroxynaphthalene as the Product of Oxidation of 1-Phenylazo-2-hydroxynaphthalene (Sudan I, Solvent Yellow 14) by Rat Liver Microsomes
1994, Vol. 59, Issue 12, pp. 2727–2733 [Abstract] - Marie Stiborová and Pavel Anzenbacher
Carcinogenic Non-Aminoazo Dye 1-Phenylazo-2-hydroxynaphthalene (Sudan I) Is Oxidized by Rat Liver Microsomal Cytochrome P-450 to Metabolites Binding to Macromolecules (Nucleic Acids and Proteins)
1992, Vol. 57, Issue 7, pp. 1537–1546 [Abstract] - Josef Chmelík, Jiří Hudeček, Karol Putyera, Jiří Makovička, Vítěz Kalous and Jitka Chmelíková
Characterization of the hydrophobic properties of amino acids on the basis of their partition and distribution coefficients in the 1-octanol-water system
1991, Vol. 56, Issue 10, pp. 2030–2041 [Abstract] - Marie Stiborová and Pavel Anzenbacher
NADH oxidation during peroxidase catalyzed metabolism of carcinogenic non-aminoazo dye 1-phenylazo-2-hydroxynaphthalene (Sudan I)
1990, Vol. 55, Issue 9, pp. 2321–2327 [Abstract] - Marie Stiborová, Befekadu Asfaw and Pavel Anzenbacher
Ce(IV)-mediated formation of benzenediazonium ion from a non-aminoazo dye, 1-phenylazo-2-hydroxy-naphthalene (Sudan I) and its binding to DNA
1989, Vol. 54, Issue 7, pp. 2021–2026 [Abstract] - Marie Stiborová, Světlana Kšinská and Sylva Leblová
Mechanism of action of NaCl on maize alcohol dehydrogenase and phosphoenolpyruvate carboxylase
1987, Vol. 52, Issue 12, pp. 3024–3033 [Abstract] - Marie Stiborová and Sylva Leblová
Effect of heterocyclic compounds and 2-mercaptoethanol on rape alcohol dehydrogenase
1987, Vol. 52, Issue 8, pp. 2107–2113 [Abstract] - Marie Stiborová, Marta Doubravová, Alena Březinová and Aleš Friedrich
Effect of heavy metal ions on barley ribulose-1,5-bisphosphate carboxylase
1987, Vol. 52, Issue 2, pp. 525–534 [Abstract] - Marie Stiborová and Sylva Leblová
Mechanism of action of heavy metals, S-triazine herbicides and nitrates on alcohol dehydrogenase from rape
1986, Vol. 51, Issue 8, pp. 1781–1788 [Abstract] - Marie Stiborová and Sylva Leblová
Iodoacetate inactivation of rape alcohol dehydrogenase
1980, Vol. 45, Issue 5, pp. 1601–1607 [Abstract] - Sylva Leblová, Noemi Nováková and Marie Stiborová
Effect of metal ions on pea alcohol dehydrogenase
1979, Vol. 44, Issue 3, pp. 799–803 [Abstract] - Marie Stiborová, Roman Lapka, Noemi Nováková and Sylva Leblová
Pea alcohol dehydrogenase: Substrate specificity and binding of coenzyme to enzyme
1979, Vol. 44, Issue 2, pp. 631–636 [Abstract] - Marie Stiborová and Sylva Leblová
Studies on binding site of alcohol dehydrogenase from rape seedlings
1978, Vol. 43, Issue 8, pp. 2217–2223 [Abstract]