Collect. Czech. Chem. Commun.
2007, 72, 1398-1406
https://doi.org/10.1135/cccc20071398
Electrode Reaction of Adriamycin Interpreted as Two Consecutive Electron Transfers with Stabilization of the Intermediate
Šebojka Komorsky-Lovrić* and Milivoj Lovrić
Department for Marine and Environmental Research, "Ruđer Bošković" Institute, P.O. Box 180, 10002 Zagreb, Croatia
Abstract
In cyclic voltammetry of adriamycin (doxorubicin hydrochloride) adsorbed on graphite electrode surface, the response of quinone/hydroquinone redox centers is split into two pairs of peaks because of inactivation of semiquinone intermediates by the hydrogen bonds.
Keywords: Adriamycin; Doxorubicin; Surface ECE mechanism; Quinone/hydroquinone redox couple; Cyclic voltammetry; Graphite electrode; Electroreduction; Electrochemistry.
References: 39 live references.
