Collect. Czech. Chem. Commun.
2007, 72, 965-983
https://doi.org/10.1135/cccc20070965
Bifunctional Acyclic Nucleoside Phosphonates: 2. Symmetrical 2-{[Bis(phosphono)methoxy]methyl}ethyl Derivatives of Purines and Pyrimidines
Silvie Vrbková*, Martin Dračínský and Antonín Holý
Centre for New Antivirals and Antineoplastics, Gilead Sciences & IOCB Research Centre, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Flemingovo nám. 2, 166 10 Prague 6, Czech Republic
Crossref Cited-by Linking
- Doleželová Eva, Klejch Tomáš, Špaček Petr, Slapničková Martina, Guddat Luke, Hocková Dana, Zíková Alena: Acyclic nucleoside phosphonates with adenine nucleobase inhibit Trypanosoma brucei adenine phosphoribosyltransferase in vitro. Sci Rep 2021, 11. <https://doi.org/10.1038/s41598-021-91747-6>
- Keough Dianne T., Špaček Petr, Hocková Dana, Tichý Tomáš, Vrbková Silvie, Slavětínská Lenka, Janeba Zlatko, Naesens Lieve, Edstein Michael D., Chavchich Marina, Wang Tzu-Hsuan, de Jersey John, Guddat Luke W.: Acyclic Nucleoside Phosphonates Containing a Second Phosphonate Group Are Potent Inhibitors of 6-Oxopurine Phosphoribosyltransferases and Have Antimalarial Activity. J. Med. Chem. 2013, 56, 2513. <https://doi.org/10.1021/jm301893b>
- Keough Dianne T., Hocková Dana, Rejman Dominik, Špaček Petr, Vrbková Silvie, Krečmerová Marcela, Eng Wai Soon, Jans Harmen, West Nicholas P., Naesens Lieve M. J., de Jersey John, Guddat Luke W.: Inhibition of the Escherichia coli 6-Oxopurine Phosphoribosyltransferases by Nucleoside Phosphonates: Potential for New Antibacterial Agents. J. Med. Chem. 2013, 56, 6967. <https://doi.org/10.1021/jm400779n>
- Vrbkova Silvie, Dracinsky Martin, Holy Antonin: Bifunctional Acyclic Nucleoside Phosphonates. Part 2. Symmetrical 2‐{[Bis(phosphono)methoxy]methyl}ethyl Derivatives of Purines and Pyrimidines. ChemInform 2007, 38. <https://doi.org/10.1002/chin.200749204>
- Vrbková Silvie, Dračínský Martin, Holý Antonín: Bifunctional acyclic nucleoside phosphonates: synthesis of chiral 9-{3-hydroxy[1,4-bis(phosphonomethoxy)]butan-2-yl} derivatives of purines. Tet Asymm 2007, 18, 2233. <https://doi.org/10.1016/j.tetasy.2007.09.021>
