Collect. Czech. Chem. Commun.
2011, 76, 1223-1238
https://doi.org/10.1135/cccc2011085
Published online 2011-09-22 09:11:23
Modeling of the ribonucleotide reductases substrate reaction. Hydrogen atom abstraction by a thiyl free radical and detection of the ribosyl-based carbon radical by pulse radiolysis
Stanislaw F. Wnuka,*, Jaidev A. K. Penjarlaa, Thao Danga, Alexander M. Mebela, Thomas Nauserb and Christian Schöneichc
a Department of Chemistry and Biochemistry, Florida International University, Miami, Florida 33199, USA
b Department of Chemistry and Applied Bioscience, ETH Zurich, CH-8093, Switzerland
c Department of Pharmaceutical Chemistry, University of Kansas, Lawrence, Kansas 66047, USA
Crossref Cited-by Linking
- Wnuk Stanislaw F., Mudgal Mukesh M., Nowak Ireneusz, Robins Morris J.: Model Substrate/Inactivation Reactions for MoaA and Ribonucleotide Reductases: Loss of Bromo, Chloro, or Tosylate Groups from C2 of 1,5-Dideoxyhomoribofuranoses upon Generation of an α-Oxy Radical at C3. Molecules 2020, 25, 2539. <https://doi.org/10.3390/molecules25112539>
- Osburn Sandra, Speciale Gaetano, Williams Spencer J., O’Hair Richard A. J.: Gas-Phase Intercluster Thiyl-Radical Induced C–H Bond Homolysis Selectively Forms Sugar C2-Radical Cations of Methyl D-Glucopyranoside: Isotopic Labeling Studies and Cleavage Reactions. J. Am. Soc. Mass Spectrom. 2017, 28, 1425. <https://doi.org/10.1007/s13361-017-1667-2>
- Dragičević Ivan, Barić Danijela, Kovačević Borislav, Golding Bernard T., Smith David M.: Non‐enzymatic Ribonucleotide Reduction in the Prebiotic Context. Chemistry A European J 2015, 21, 6132. <https://doi.org/10.1002/chem.201405741>
- Osburn Sandra, Williams Spencer J., O’Hair Richard A.J.: Formation of sugar radical cations from collision-induced dissociation of non-covalent complexes with S-nitroso thiyl radical precursors. International Journal of Mass Spectrometry 2015, 378, 95. <https://doi.org/10.1016/j.ijms.2014.07.020>
- Adhikary Amitava, Kumar Anil, Rayala Ramanjaneyulu, Hindi Ragda M., Adhikary Ananya, Wnuk Stanislaw F., Sevilla Michael D.: One-Electron Oxidation of Gemcitabine and Analogs: Mechanism of Formation of C3′ and C2′ Sugar Radicals. J. Am. Chem. Soc. 2014, 136, 15646. <https://doi.org/10.1021/ja5083156>
