- ISSN 0010-0765 printed
- ISSN 1212-6950 electronic
I. Votruba
- H. Dvořáková, A. Holý, M. Masojídková, I. Votruba, J. Balzarini, R. Snoeck and E. De Clercq
Synthesis and antiviral activity of acyclic nucleoside and nucleotide derivatives of 8-azaadenine
1993, Vol. 58, Special Issue, pp. S253–S255 [Abstract] - A. Holý and I. Votruba
Substrate specificity of bacterial thymidylate-synthetase
1974, Vol. 39, Issue 6, pp. 1646–1661 [Abstract] - J. Škoda, I. Votruba and J. Farkaš
Study of the mechanism of the growth-inhibiting effect of 3-oxauracil in Escherichia coli
1974, Vol. 39, Issue 6, pp. 1500–1509 [Abstract] - A. Holý, I. Votruba and K. Jošt
S-(Pyrimidin-2-yl)-L-cysteine: Chemical synthesis and biosynthesis in Escherichia coli
1974, Vol. 39, Issue 2, pp. 634–646 [Abstract] - I. Votruba, A. Holý and H. Pischel
Inhibition of DNA synthesis in Escherichia coli by 1-(β-D-ribofuranosyl)-2-pyrimidone
1972, Vol. 37, Issue 7, pp. 2213–2220 [Abstract] - I. Votruba and D. Grünberger
Formation and properties of submethylated ribonucleoprotein particles from 8-azaguanine treated Bacillus cereus
1970, Vol. 35, Issue 12, pp. 3747–3756 [Abstract] - I. Votruba and D. Grünberger
Accumulation of submethylated ribonucleoprotein particles from 8-azaguanine treated Bacillus cereus
1969, Vol. 34, Issue 1, pp. 295–304 [Abstract]
The following names might also represent this author:
Ivan Votruba
- Martin Křováček, Hana Dvořáková, Ivan Votruba, Ivana Císařová and Dalimil Dvořák*
6-Alkynylpurines bearing electronacceptor substituents: Preparation, reactivity in cycloaddition reactions and cytostatic activity
2011, Vol. 76, Issue 12, pp. 1487–1527 [Abstract] - Petr Jansa*, Petr Špaček, Ivan Votruba, Petra Břehová, Martin Dračínský, Blanka Klepetářová and Zlatko Janeba
Efficient one-pot synthesis of polysubstituted 6-[(1H-1,2,3-triazol-1-yl)methyl]uracils through the “click” protocol
2011, Vol. 76, Issue 9, pp. 1121–1131 [Abstract] - Ivan Votruba*, Jana Trýznová, Petra Břehová, Eva Tloušťová, Květoslava Horská, Jindřich Fanfrlík, Ondřej Přenosil and Antonín Holý
Inhibition of human purine nucleoside phosphorylase by tenofovir phosphate congeners
2010, Vol. 75, Issue 12, pp. 1249–1257 [Abstract] - Vojtěch Balšánek, Lucie Tichotová, Jiří Kuneš, Marcel Špulák, Milan Pour*, Ivan Votruba and Vladimír Buchta
Cytostatic tetrazole–butenolide conjugates: linking tetrazole and butenolide rings via stille coupling and biological activity of the target substances
2009, Vol. 74, Issue 7-8, pp. 1161–1178 [Abstract] - Markéta Schinkmanová*, Ivan Votruba, Riri Shibata, Bin Han, Xiaohong Liu, Tomas Cihlar and Antonín Holý
Human N6-Methyl-AMP/DAMP Aminohydrolase (Abacavir 5'-Monophosphate Deaminase) is Capable of Metabolizing N6-Substituted Purine Acyclic Nucleoside Phosphonates
2008, Vol. 73, Issue 2, pp. 275–291 [Abstract] - Peter Šilhár, Radek Pohl, Ivan Votruba, Blanka Klepetářová and Michal Hocek*
Synthesis of 6-Amino-, 6-Methyl- and 6-Aryl-2-(hydroxymethyl)purine Bases and Nucleosides
2006, Vol. 71, Issue 6, pp. 788–803 [Abstract] - Karel Pomeisl*, Ivan Votruba, Antonín Holý and Radek Pohl
Syntheses of Base and Side-Chain Modified Pyrimidine 1-[2-(Phosphonomethoxy)propyl] Derivatives as Potent Inhibitors of Thymidine Phosphorylase (PD-ECGF) from SD-Lymphoma
2006, Vol. 71, Issue 4, pp. 595–624 [Abstract] - Květoslava Horská, Ivan Votruba* and Antonín Holý
Interaction of Phosphates of the Acyclic Nucleoside Phosphonates with Nucleoside Diphosphate Kinase from Yeast and Bovine Liver
2006, Vol. 71, Issue 1, pp. 35–43 [Abstract] - Peter Šilhár, Radek Pohl, Ivan Votruba and Michal Hocek*
Synthesis of 2-Substituted 6-(Hydroxymethyl)purine Bases and Nucleosides
2005, Vol. 70, Issue 10, pp. 1669–1695 [Abstract] - Karel Pomeisl*, Radek Pohl, Antonín Holý and Ivan Votruba
Simple Transformation of Thymine 1-[3-Hydroxy-2-(phosphonomethoxy)propyl] Derivatives to Their 1-[3-Fluoro-2-(phosphonomethoxy)propyl] Counterparts
2005, Vol. 70, Issue 9, pp. 1465–1481 [Abstract] - Pavel Turek, Martin Kotora*, Michal Hocek* and Ivan Votruba
Novel Method for Preparation of Highly Substituted 6-Arylpurines by Reactions of 6-Alkynylpurines with Zirconacyclopentadienes
2005, Vol. 70, Issue 3, pp. 339–349 [Abstract] - Petr Nauš, Ivan Votruba and Michal Hocek*
Covalent Analogues of DNA Base-Pairs and Triplets VII. Synthesis and Cytostatic Activity of Bis(purin-6-yl)acetylene and -diacetylene Nucleosides
2004, Vol. 69, Issue 10, pp. 1955–1970 [Abstract] - Alois Pískala*, Naeem B. Hanna, Milena Masojídková, Pavel Fiedler and Ivan Votruba
Synthesis of N4-Amino and N4-Hydroxy Derivatives of 5-Azacytidine. A Facile Rearrangement of the N4-Amino Derivative to 5-(3-β-D-Ribofuranosylureido)-1H-1,2,4-triazole
2004, Vol. 69, Issue 4, pp. 905–917 [Abstract] - Petr Čapek, Miroslav Otmar*, Milena Masojídková, Ivan Votruba and Antonín Holý
A Facile Synthesis of 9-Deaza Analogue of Olomoucine
2003, Vol. 68, Issue 4, pp. 779–791 [Abstract] - Gabriel Birkuš, Ivan Votruba*, Miroslav Otmar and Antonín Holý
Interactions of 1-[(S)-3-Hydroxy-2-(phosphonomethoxy)propyl]cytosine (Cidofovir) Diphosphate with DNA Polymerases α, δ and ε*
2001, Vol. 66, Issue 11, pp. 1698–1706 [Abstract] - Antonín Holý*, Ivan Votruba, Eva Tloušťová and Milena Masojídková
Synthesis and Cytostatic Activity of N-[2-(Phosphonomethoxy)alkyl] Derivatives of N6-Substituted Adenines, 2,6-Diaminopurines and Related Compounds
2001, Vol. 66, Issue 10, pp. 1545–1592 [Abstract] - Miroslav Otmar*, Milena Masojídková, Ivan Votruba and Antonín Holý
An Alternative Synthesis of HPMPC and HPMPA Diphosphoryl Derivatives
2001, Vol. 66, Issue 3, pp. 500–506 [Abstract] - Michal Hocek*, Antonín Holý, Ivan Votruba and Hana Dvořáková
Cytostatic 6-Arylpurine Nucleosides III. Synthesis and Structure-Activity Relationship Study in Cytostatic Activity of 6-Aryl-, 6-Hetaryl- and 6-Benzylpurine Ribonucleosides
2001, Vol. 66, Issue 3, pp. 483–499 [Abstract] - Michal Hocek*, Antonín Holý, Ivan Votruba and Hana Dvořáková
Cytostatic 6-Arylpurine Nucleosides II. Synthesis of Sugar-Modified Derivatives: 9-(2-Deoxy-β-D-erythro-pentofuranosyl)-, 9-(5-Deoxy-β-D-ribofuranosyl)- and 9-(2,3-Dihydroxypropyl)-6-phenylpurines
2000, Vol. 65, Issue 11, pp. 1683–1697 [Abstract] - Romana Krejčová, Květoslava Horská, Ivan Votruba* and Antonín Holý
Phosphorylation of Purine (Phosphonomethoxy)alkyl Derivatives by Mitochondrial AMP Kinase (AK2 Type) from L1210 Cells
2000, Vol. 65, Issue 10, pp. 1653–1668 [Abstract] - Romana Krejčová, Květoslava Horská, Ivan Votruba* and Antonín Holý
Isoenzymes of GMP Kinase from L1210 Cells: Isolation and Characterization
1999, Vol. 64, Issue 3, pp. 559–570 [Abstract] - Gabriel Birkuš, Pavel Kramata, Ivan Votruba, Berta Otová, Miroslav Otmar and Antonín Holý
Nonproteolyzed Form of DNA-Polymerase ε from T-Cell Spontaneous Lymphoma of Sprague-Dawley Inbred Rat: Isolation and Characterization
1998, Vol. 63, Issue 5, pp. 723–731 [Abstract] - Lenka Olšanská, Tomas Cihlar, Ivan Votruba* and Antonín Holý
Transport of Adefovir (PMEA) in Human T-Lymphoblastoid Cells
1997, Vol. 62, Issue 5, pp. 821–828 [Abstract] - Pavel Kramata, Gabriel Birkuš, Miroslav Otmar, Ivan Votruba and Antonín Holý
Structural features of acyclic nucleotide analogs conferring inhibitory effects on cellular replicative DNA polymerases
1996, Vol. 61, Special Issue, pp. S188–S191 [Abstract] - Antonín Holý, Zdeněk Zídek and Ivan Votruba
Inhibition of murine lymphocyte proliferation by N6-substituted acyclic purine nucleoside phosphonates
1996, Vol. 61, Special Issue, pp. S182–S187 [Abstract] - Romana Krejčová, Květoslava Horská, Ivan Votruba and Antonín Holý
Phosphorylation of phosphonomethoxyalkylguanines by GMP-kinase isoenzymes
1996, Vol. 61, Special Issue, pp. S134–S136 [Abstract] - Pavel Kramata, Jaroslav Černý, Gabriel Birkuš, Ivan Votruba, Berta Otová and Antonín Holý
DNA-Polymerases α, δ and ε from T-Cell Spontaneous Lymphoblastic Leukemia of Sprague-Dawley Inbred Rat: Isolation and Characterization
1995, Vol. 60, Issue 9, pp. 1555–1572 [Abstract] - Ivan Votruba, Antonín Holý, Hana Dvořáková, Jaroslav Günter, Dana Hocková, Hubert Hřebabecký, Tomas Cihlar and Milena Masojídková
Synthesis of 2-Deoxy-β-D-ribonucleosides and 2,3-Dideoxy-β-D-pentofuranosides on Immobilized Bacterial Cells
1994, Vol. 59, Issue 10, pp. 2303–2330 [Abstract] - Hana Dvořáková, Antonín Holý, Ivan Votruba and Milena Masojídková
Synthesis and Biological Effects of Acyclic Analogs of Deazapurine Nucleosides
1993, Vol. 58, Issue 3, pp. 629–648 [Abstract] - Pavel Kramata and Ivan Votruba
Enzymes of Human Herpesviruses
1992, Vol. 57, Issue 8, pp. 1577–1612 [Abstract] - Tomas Cihlar, Ivan Votruba, Květoslava Horská, Radek Liboska, Ivan Rosenberg and Antonín Holý
Metabolism of 1-(S)-(3-Hydroxy-2-phosphonomethoxypropyl)cytosine (HPMPC) in Human Embryonic Lung Cells
1992, Vol. 57, Issue 3, pp. 661–672 [Abstract] - Katarina Šedivá, Ivan Votruba, Antonín Holý and Ivan Rosenberg
Purine nucleoside phosphorylase: Isolation and characterization
1990, Vol. 55, Issue 12, pp. 2987–2999 [Abstract] - Antonín Holý, Masahiko Nishizawa, Ivan Rosenberg and Ivan Votruba
The effect of phosphonylmethyl analogs of ribonucleoside 5'-diphosphates on (E. coli) polynucleotide phosphorylase catalyzed reactions
1987, Vol. 52, Issue 12, pp. 3042–3057 [Abstract] - Antonín Holý, Joachim König, Jiří Veselý, Dieter Cech, Ivan Votruba and Erik De Clercq
5'-O-Alkyl-5-fluorouridines: Synthesis and biological activity
1987, Vol. 52, Issue 6, pp. 1589–1608 [Abstract] - Antonín Holý, Jitka Kohoutová, Aleš Merta and Ivan Votruba
9-(Aminoalkyl)-8-hydroxyadenines: Preparation, mechanism of formation and use in affinity chromatography of S-adenosyl-L-homocysteine hydrolase
1986, Vol. 51, Issue 2, pp. 459–477 [Abstract] - Antonín Holý, Anita Ludziša, Ivan Votruba, Kateřina Šedivá and Helmut Pischel
Preparation of analogues of cytosine and 2-pyrimidinone nucleosides and their effect on bacterial (Escherichia coli A 19) cytidine aminohydrolase
1985, Vol. 50, Issue 2, pp. 393–417 [Abstract] - Antonín Holý, Ivan Votruba and Erik De Clercq
Structure-activity studies on open-chain analogues of nucleosides: Inhibition of S-adenosyl-L-homocysteine hydrolase and antiviral activity 2. Acid open-chain analogues
1985, Vol. 50, Issue 1, pp. 262–279 [Abstract] - Antonín Holý, Ivan Votruba and Erik De Clercq
Structure-activity studies on open-chain analogues of nucleosides: Inhibition of S-adenosyl-L-homocysteine hydrolase and antiviral activity 1. Neutral open-chain analogues
1985, Vol. 50, Issue 1, pp. 245–261 [Abstract] - Ladislava Šebestová, Ivan Votruba and Antonín Holý
S-adenosine-L-homocysteine hydrolase from Nicotiana tabacum L.: Isolation and properties
1984, Vol. 49, Issue 6, pp. 1543–1551 [Abstract] - Aleš Merta, Ivan Votruba, Jiří Veselý and Antonín Holý
S-adenosyl-L-homocysteine hydrolase from mouse leukemic cells: Isolation and properties
1983, Vol. 48, Issue 9, pp. 2701–2708 [Abstract] - Ivan Votruba, Antonín Holý and Ivan Rosenberg
Affinity chromatography of rat liver S-adenosyl-L-homocysteine hydrolase
1983, Vol. 48, Issue 9, pp. 2549–2557 [Abstract] - Antonín Holý, Ivan Votruba and Erik De Clercq
Synthesis and antiviral activity of stereoisomeric eritadenines
1982, Vol. 47, Issue 5, pp. 1392–1407 [Abstract] - Ivan Votruba and Antonín Holý
Eritadenines - Novel type of potent inhibitors of S-adenosyl-L-homocysteine hydrolase
1982, Vol. 47, Issue 1, pp. 167–172 [Abstract] - Ivan Votruba and Antonín Holý
Inhibition of S-adenosyl-L-homocysteine hydrolase by the aliphatic nucleoside analogue - 9-(S)-(2,3-dihydroxypropyl)adenine
1980, Vol. 45, Issue 11, pp. 3039–3044 [Abstract] - Petr Jansa, Petr Špaček, Antonín Holý, Ivan Votruba and Zlatko Janeba
Efficient one-pot synthesis of polysubstituted 6-[(1H-1,2,3-triazol-1-yl)methyl]uracils through the "click" protocol
Symposium Series 2011, Vol. 12, pp. 467–468 [Abstract]
Published online 2015-08-20 10:24:43 - David Mařák, Miroslav Otmar, Martin Dračínský, Ivan Votruba and Antonín Holý
Nucleosides and nucleotides containing 8-aza-7,9-dideazaxanthine
Symposium Series 2008, Vol. 10, pp. 426–428 [Abstract]
Published online 2015-10-30 18:44:11 - Radim Nencka, Hubert Hřebabecký, Ivan Votruba, Martin Dračínský and Antonín Holý
Metalation of 6-halo-2,4-dimethoxypyrimidines as the key step for the synthesis of biologicaly active compounds
Symposium Series 2008, Vol. 10, pp. 249–253 [Abstract]
Published online 2015-10-30 18:38:37 - Karel Pomeisl, Antonín Holý, Ivan Votruba, Radim Nencka and Radek Pohl
Facile syntheses of pyrimidine acyclic nucleoside phosphonates and their potential evaluation for biomedical applications
Symposium Series 2008, Vol. 10, pp. 201–205 [Abstract]
Published online 2015-10-30 18:37:39 - Markéta Schinkmanová, Ivan Votruba and Antonín Holý
N6-methyl-AMP hydrolase activates N6-substituted purine ANPs
Symposium Series 2005, Vol. 7, pp. 463–464 [Abstract]
Published online 2015-11-08 11:58:20 - Radim Nencka, Ivan Votruba, Hubert Hřebabecký, Eva Tloušťová, Květa Horská, Milena Masojídková and Antonín Holý
Design and synthesis of 5,6-disubstituted uracil derivatives as potent inhibitors of thymidine phosphorylase
Symposium Series 2005, Vol. 7, pp. 441–442 [Abstract]
Published online 2015-11-08 11:57:40 - Petr Kočalka, Markéta Rinnová, Václav Vaněk, Dominik Rejman, Ivan Votruba, Ivana Tomečková, Šárka Králíková, Magdalena Petrová, Ondřej Páv, Radek Pohl, Miloš Buděšínský, Radek Liboska, Zdeněk Točík and Ivan Rosenberg
Novel nucleoside phosphonic acids-based inhibitors of thymidine phosphorylase
Symposium Series 2005, Vol. 7, pp. 415–416 [Abstract]
Published online 2015-11-08 11:56:57 - Miroslav Hájek, Naděžda Matulová, Ivan Votruba, Antonín Holý and Eva Tloušťová
Acyclic nucleoside phosphonates and human telomerase inhibition
Symposium Series 2005, Vol. 7, pp. 373–374 [Abstract]
Published online 2015-11-08 11:55:35 - Peter Šilhár, Radek Pohl, Ivan Votruba and Michal Hocek
Synthesis and transformations of 6-(hydroxymethyl)purines
Symposium Series 2005, Vol. 7, pp. 221–224 [Abstract]
Published online 2015-11-08 11:52:45 - Ivan Rosenberg, Ivan Barvik, Miloš Buděšínský, Petr Kočalka, Šárka Králíková, Radek Liboska, Ondřej Pačes, Ondřej Páv, Magdalena Petrová, Radek Pohl, Martina Pressová, Dominik Rejman, Ivan Votruba and Zdeněk Točík
Nucleoside phosphonic acids and related oligonucleotides: Structural diversity vs biological properties
Symposium Series 2005, Vol. 7, pp. 153–157 [Abstract]
Published online 2015-11-08 11:51:38 - Miroslav Otmar, Milena Masojídková, Ivan Votruba and Antonín Holý
Synthesis and cytostatic activity of 2,6-diamino-9-benzyl-9-deazapurine and related compounds
Symposium Series 2002, Vol. 5, pp. 38–39 [Abstract]
Published online 2016-01-25 20:38:21 - Gabriel Birkuš, Ivan Votruba, Antonín Holý and Berta Otová
HPMPApp as a substrate toward replicative DNA polymerases α, δ and ε
Symposium Series 1999, Vol. 2, pp. 289–293 [Abstract]
Published online 2016-05-08 23:33:04 - Romana Krejčová, Květoslava Horská, Ivan Votruba and Antonín Holý
Phosphorylation of enantiomers of HPMPG
Symposium Series 1999, Vol. 2, pp. 286–288 [Abstract]
Published online 2016-05-08 23:32:58 - Miroslav Otmar, Ivan Votruba and Antonín Holý
An alternative synthesis of HPMPC and HPMPA diphosphoryl derivatives
Symposium Series 1999, Vol. 2, pp. 252–254 [Abstract]
Published online 2016-05-08 23:31:40 - Michal Hocek, Martina Havelková, Dalimil Dvořák, Antonín Holý and Ivan Votruba
Synthesis of 6-phenylpurine bases and nucleosides by Suzuki–Miyaura cross-coupling reactions of 6-chloropurines with substituted phenylboronic acids
Symposium Series 1999, Vol. 2, pp. 27–30 [Abstract]
Published online 2016-05-08 20:40:17
Ivan Votruba, Antonín Ho
- Karel Pomeisl, Ivan Votruba, Antonín Ho and Radek Pohl
Pyrimidine 1-[2-(phosphonomethoxy)propyl] derivatives: Their syntheses and utilization as potent inhibitors of thymidine phosphorylase (PD-ECGF) from SD-lymphoma
Symposium Series 2005, Vol. 7, pp. 291–295 [Abstract]
Published online 2015-11-08 11:54:12
