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Antivirals

• Taťána Majerová*, Hillary Hoffman and Filip Majer
  Therapeutic targets for influenza – perspectives in drug development
  2010, Vol. 75, Issue 1, pp. 81–103 [Abstract]
• Hubert Hřebabecký*, Martin Dračínský, Armando M. De Palma, Johan Neyts and Antonín Holý
  Synthesis of novel racemic carbocyclic nucleoside analogues derived from 4,8-dioxatricyclo[4.2.1.0^3,7]nonane-9-methanol and 4-oxatricyclo[4.3.1.0^3,7]decane-10-methanol, compounds with activity against Coxsackie viruses
  2009, Vol. 74, Issue 3, pp. 469–485 [Abstract]
• Hubert Hřebabecký*, Martin Dračínský and Antonín Holý
  Synthesis of Novel Carbocyclic Nucleoside Analogues Containing Bicyclo[2.2.1]hept-2-ene-2-methanol
  2008, Vol. 73, Issue 1, pp. 44–58 [Abstract]
• Milan Dejmek, Hubert Hřebabecký*, Martin Dračínský and Antonín Holý
  Synthesis of Novel Carbocyclic Nucleoside Analogues Derived from 2-(Hydroxymethyl)bicyclo[2.2.1]heptane
  2007, Vol. 72, Issue 11, pp. 1523–1544 [Abstract]
• Marcela Krečmerová*, Antonín Holý and Milena Masojídková
  Pyrimidine Acyclic Nucleotide Analogues with Aromatic Substituents in C-5 Position
  2007, Vol. 72, Issue 7, pp. 927–951 [Abstract]
• Michal Hocek*, Peter Šilhár and Radek Pohl
  Cytostatic and Antiviral 6-Arylpurine Ribonucleosides VIII. Synthesis and Evaluation of 6-Substituted Purine 3'-Deoxyribonucleosides
  2006, Vol. 71, Issue 10, pp. 1484–1496 [Abstract]
• Michal Pechar*, Alena Braunová, Vladimír Šubr, Karel Ulbrich and Antonín Holý
  Polymeric Conjugates of 9-[2-(Phosphonomethoxy)ethyl]purine with Potential Antiviral and Cytostatic Activity
  2006, Vol. 71, Issue 8, pp. 1211–1220 [Abstract]
• Minmin Yang, Tesfaye Serbessa and Stewart W. Schneller*
  The 3-Deaza and 7-Deaza Derivatives of 5'-Amino-5'-deoxy-5'-noraristeromycin
  2006, Vol. 71, Issue 7, pp. 1122–1129 [Abstract]
• Anastasiya L. Khandazhinskaya, Elena A. Shirokova, Alexander V. Shipitsin, Inna L. Karpenko, Evgenii F. Belanov, Marina K. Kukhanova and Maksim V. Yasko*
  Adenosine N¹-Oxide Analogues as Inhibitors of Orthopox Virus Replication
  2006, Vol. 71, Issue 7, pp. 1107–1121 [Abstract]
• Bastian Reichardt, Olaf R. Ludek and Chris Meier*
  New and Efficient Synthesis of Racemic Cyclopent-3-en-1-yl Nucleoside Analogues and Their Derivatives
  2006, Vol. 71, Issue 7, pp. 1011–1028 [Abstract]
• Claire Pierra, Agnès Amador, Eric Badaroux, Richard Storer and Gilles Gosselin*
  Synthesis of 2'-C-Methylcytidine and 2'-C-Methyluridine Derivatives Modified in the 3'-Position as Potential Antiviral Agents
  2006, Vol. 71, Issue 7, pp. 991–1010 [Abstract]
• Martina M. Adams, Jan W. Bats, Nadja V. Nikolaus, Myriam Witvrouw, Zeger Debyser and Joachim W. Engels*
  Microwave-Assisted Synthesis of Fluoroquinolones and Their Nucleosides as Inhibitors of HIV Integrase
  2006, Vol. 71, Issue 7, pp. 978–990 [Abstract]
• Hubert Hřebabecký*, Milena Masojídková, Martin Dračínský and Antonín Holý
  Synthesis of Novel Conformationally Locked Carbocyclic Nucleosides Derived from 3-(Hydroxymethyl)bicyclo[2.2.1]heptane-2,5-diol
  2006, Vol. 71, Issue 6, pp. 871–888 [Abstract]
• Zhivko A. Velkov*, Yasen Zh. Velkov, Alia V. Tadjer and Ivanka G. Stankova
  Quantum-Chemical Investigations of 5-Bromo-2'-Deoxyuridine Derivatives with Antiviral Activity
  2006, Vol. 71, Issue 5, pp. 691–697 [Abstract]
• Marcela Krečmerová*, Milena Masojídková and Antonín Holý
  Preparation of C-5 Substituted Cidofovir Derivatives
  2006, Vol. 71, Issue 4, pp. 579–594 [Abstract]
• Silvie Vrbovská*, Antonín Holý, Radek Pohl and Milena Masojídková
  Bifunctional Acyclic Nucleoside Phosphonates. 1. Symmetrical 1,3-Bis[(phosphonomethoxy)propan-2-yl] Derivatives of Purines and Pyrimidines
  2006, Vol. 71, Issue 4, pp. 543–566 [Abstract]
• Květoslava Horská, Ivan Votruba* and Antonín Holý
  Interaction of Phosphates of the Acyclic Nucleoside Phosphonates with Nucleoside Diphosphate Kinase from Yeast and Bovine Liver
  2006, Vol. 71, Issue 1, pp. 35–43 [Abstract]
• Šárka Chalupová*, Antonín Holý and Milena Masojídková
  Synthesis of N⁴-Substituted Derivatives of 1-[2-(Phosphonomethoxy)ethyl]cytosine and Its Diisopropyl Ester as a Model Reaction for the Synthesis of N⁴-Substituted Derivatives of Cidofovir
  2005, Vol. 70, Issue 12, pp. 2066–2074 [Abstract]
• Karel Pomeisl*, Radek Pohl, Antonín Holý and Ivan Votruba
  Simple Transformation of Thymine 1-[3-Hydroxy-2-(phosphonomethoxy)propyl] Derivatives to Their 1-[3-Fluoro-2-(phosphonomethoxy)propyl] Counterparts
  2005, Vol. 70, Issue 9, pp. 1465–1481 [Abstract]
• Hubert Hřebabecký*, Milena Masojídková and Antonín Holý
  Synthesis of Novel Conformationally Locked Carbocyclic Nucleosides Derived from 5,5- and 6,6-Bis(hydroxymethyl)bicyclo[2.2.1]heptan-2-ol
  2005, Vol. 70, Issue 4, pp. 519–538 [Abstract]
• Dana Hocková*, Milena Masojídková and Antonín Holý
  Sonogashira Cross-Coupling in the Synthesis of Acyclic Nucleoside Phosphonates: Preparation of 6-[(Phosphonomethoxy)alkynyl]- and 6-[(Phosphonomethoxy)alkyl]pyrimidines
  2005, Vol. 70, Issue 2, pp. 247–258 [Abstract]
• Hubert Hřebabecký*, Milena Masojídková and Antonín Holý
  Synthesis of Racemic 9-(6- and 2,6-Substituted 9H-Purin-9-yl)-5-oxatricyclo[4.2.1.0^3,7]nonane-3-methanols, Novel Conformationally Locked Carbocyclic Nucleosides
  2005, Vol. 70, Issue 1, pp. 103–123 [Abstract]
• Marcela Krečmerová*, Milena Masojídková and Antonín Holý
  Synthesis of N⁹- and N⁷-[2-Hydroxy-3-(phosphonomethoxy)propyl] Derivatives of N⁶-Substituted Adenines, 2,6-Diaminopurines and Related Compounds
  2004, Vol. 69, Issue 10, pp. 1889–1913 [Abstract]
• Marcela Krečmerová*, Miloš Buděšínský, Milena Masojídková and Antonín Holý
  Synthesis of Optically Active N⁶-Alkyl Derivatives of (R)-3-(Adenin-9-yl)-2-hydroxypropanoic Acid and Related Compounds
  2003, Vol. 68, Issue 5, pp. 931–950 [Abstract]
• Hubert Hřebabecký*, Milena Masojídková and Antonín Holý
  Synthesis of Racemic 2-Hydroxy-4- and 2-Hydroxy-5-(hydroxymethyl)cyclohexane Nucleoside Analogues
  2002, Vol. 67, Issue 11, pp. 1681–1699 [Abstract]
• Feng-Ling Qing*, Jiang Yu and Xiang-Kai Fu
  Synthesis of 2',3'-Dideoxy-2'-trifluoromethyl-N-azanucleosides
  2002, Vol. 67, Issue 9, pp. 1267–1276 [Abstract]
• Gabriel Birkuš, Ivan Votruba*, Miroslav Otmar and Antonín Holý
  Interactions of 1-[(S)-3-Hydroxy-2-(phosphonomethoxy)propyl]cytosine (Cidofovir) Diphosphate with DNA Polymerases α, δ and ε*
  2001, Vol. 66, Issue 11, pp. 1698–1706 [Abstract]
• Zlatko Janeba*, Antonín Holý and Milena Masojídková
  Synthesis of 8-Amino- and N-Substituted 8-Aminoadenine Derivatives of Acyclic Nucleoside and Nucleotide Analogs
  2001, Vol. 66, Issue 3, pp. 517–532 [Abstract]
• Petr Alexander*, Antonín Holý, Miloš Buděšínský and Milena Masojídková
  Synthesis of Acyclic Nucleotide Analogues Derived from N³-Substituted Isoguanine
  2000, Vol. 65, Issue 11, pp. 1713–1725 [Abstract]
• Romana Krejčová, Květoslava Horská, Ivan Votruba* and Antonín Holý
  Phosphorylation of Purine (Phosphonomethoxy)alkyl Derivatives by Mitochondrial AMP Kinase (AK2 Type) from L1210 Cells
  2000, Vol. 65, Issue 10, pp. 1653–1668 [Abstract]
• Michal Česnek, Michal Hocek* and Antonín Holý
  Synthesis of Acyclic Nucleotide Analogues Derived from 2-Amino-6-C-substituted Purines via Cross-Coupling Reactions of 2-Amino-9-{2-[(diisopropoxyphosphoryl)methoxy]ethyl}-6-halopurines with Diverse Organometallic Reagents
  2000, Vol. 65, Issue 8, pp. 1357–1373 [Abstract]
• Dana Hocková*, Milena Masojídková and Antonín Holý
  7-(1-Cyanobut-3-en-1-yl)-N⁶-[(N,N-dimethylamino)methylene]adenine as a Starting Compound for the Synthesis of α-Branched Acyclic Analogues of N⁷-Isomer of Adenosine
  1999, Vol. 64, Issue 8, pp. 1316–1324 [Abstract]
• Antonín Holý*, Miloš Buděšínský, Jaroslav Podlaha and Ivana Císařová
  Synthesis of Quaternary 1-[2-(Phosphonomethoxy)ethyl] Derivatives of 2,4-Diaminopyrimidine and Related Acyclic Nucleotide Analogs
  1999, Vol. 64, Issue 2, pp. 242–256 [Abstract]
• Hubert Hřebabecký, Jan Balzarini and Antonín Holý
  Preparation of Chloro and Sulfanyl Derivatives of 1-(2-Deoxy-4-C-hydroxymethyl-α-L-threo-Pentofuranosyl)uracil
  1997, Vol. 62, Issue 7, pp. 1114–1127 [Abstract]
• Michal Hocek, Milena Masojídková and Antonín Holý
  Synthesis of Acyclic Nucleotide Analogues Derived from 6-Hetarylpurines via Cross-Coupling Reactions of 9-[2-(Diethoxyphosphonylmethoxy)ethyl]-6-iodopurine with Hetaryl Organometallic Reagents
  1997, Vol. 62, Issue 1, pp. 136–146 [Abstract]
• Michal Hocek, Milena Masojídková, Antonín Holý, Graciela Andrei, Robert Snoeck, Jan Balzarini and Erik De Clercq
  Synthesis and Antiviral Activity of Acyclic Nucleotide Analogues Derived from 6-(Aminomethyl)purines and Purine-6-carboxamidines
  1996, Vol. 61, Issue 10, pp. 1525–1537 [Abstract]
• Radek Liboska, Milena Masojídková and Ivan Rosenberg
  Carbocyclic Phosphonate-Based Nucleotide Analogs Related to PMEA II. Racemic cis-Configured Derivatives
  1996, Vol. 61, Issue 5, pp. 778–790 [Abstract]
• Radek Liboska, Milena Masojídková and Ivan Rosenberg
  Carbocyclic Phosphonate-Based Nucleotide Analogs Related to PMEA. I. Racemic trans-Configured Derivatives
  1996, Vol. 61, Issue 2, pp. 313–332 [Abstract]

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