Collection Symposium Series 2008, 10, 401-403
https://doi.org/10.1135/css200810401
Published online 2015-10-30 18:43:25

4-Oxoheptanedioic acid linker in the synthesis of base-sensitive oligonucleotides

Anna Leisvuori, Päivi Poijärvi-Virta, Pasi Virta and Harri Lönnberg

Individual author index pages


Other CCCC articles of these authors

  • Mikko Ora, Johanna Järvi, Mikko Oivanen and Harri Lönnberg
    Hydrolytic reactions of the phosphorodithioate analog of uridylyl(3',5')uridine: Cleavage, desulfurization and isomerization
    Symposium Series 1999, Vol. 2, pp. 230–232 [Abstract]
    Published online 2016-05-08 23:30:50
  • Niangoran Koissi, Kari Neuvonen, Tony Munter, Leif Kronberg and Harri Lönnberg
    A novel fluorescent base modification by reaction of guanosine with triformylmethane
    Symposium Series 1999, Vol. 2, pp. 228–229 [Abstract]
    Published online 2016-05-08 23:30:43
  • Mohamed I. Elzagheid, Kati Mattila, Mikko Oivanen, Bryan C. N. M. Jones, Richard Cosstick and Harri Lönnberg
    Hydrolytic reactions of 2',3'-dideoxy-3'-thiothymidine 3',5'-cyclic phosphorothiolate methyl ester
    Symposium Series 1999, Vol. 2, pp. 225–227 [Abstract]
    Published online 2016-05-08 23:30:36
  • Qi Wang, Satu Mikkola, Zoltan Jori, Mia Helkearo and Harri Lönnberg
    Bimetallic Ca2+ and Zn2+ complexes of BISDIEN: Potential catalysts of RNA cleavage
    Symposium Series 1999, Vol. 2, pp. 222–224 [Abstract]
    Published online 2016-05-08 23:30:30
  • Erkki J. Nurminen, Jorma K. Mattinen and Harri Lönnberg
    Catalysis in tetrazole-promoted phosphoramidite alcoholysis
    Symposium Series 1999, Vol. 2, pp. 219–221 [Abstract]
    Published online 2016-05-08 23:30:24
  • Satu Mikkola, Izabela Zagorowska and Harri Lönnberg
    The effect of the secondary structure of RNA on the reactivity of its phosphodiester bonds: The cleavage of phosphodiester bonds within hairpin loops in the presence and absence of metal ion catalysts
    Symposium Series 1999, Vol. 2, pp. 6–10 [Abstract]
    Published online 2016-05-08 20:39:48
  • Mohamed I. Elzagheid, Esa Mäki, Ulla Kaukinen, Mikko Oivanen and Harri Lönnberg
    Hydrolysis and intramolecular transesterification of 3'-thioinosine 3'-S-phosphorothiolate triester
    Symposium Series 1999, Vol. 2, pp. 1–5 [Abstract]
    Published online 2016-05-08 20:39:38
  • Joanna Zuberek, Janusz Stępiński, Anna Niedzwiecka, Ryszard Stolarski, Harri Salo, Harri Lönnberg and Edward Darżynkiewicz
    Synthesis of tetraribonucleotide cap analogue m7GpppAm2'pUm2'pAm2' and its interaction with eukaryotic initiation factor eIF4E
    Symposium Series 2002, Vol. 5, pp. 399–403 [Abstract]
    Published online 2016-01-25 20:52:22
  • Teija Niittymäki, Ulla Kaukinen, Pasi Virta and Harri Lönnberg
    Azacrown tethered oligonucleotides: Potential artificial RNases
    Symposium Series 2002, Vol. 5, pp. 376–378 [Abstract]
    Published online 2016-01-25 20:51:35
  • Kati Mattila, Tuomas Lönnberg, Mikko Ora, Mikko Oivanen and Harri Lönnberg
    Synthesis and hydrolytic reactions of an N3'-phosphoramidate analog of uridylyl(3',5')uridine
    Symposium Series 2002, Vol. 5, pp. 370–372 [Abstract]
    Published online 2016-01-25 20:51:23
  • Kaisa Ketomäki and Harri Lönnberg
    Mixed-phase hybridization of short oligodeoxyribonucleotides on microscopic polymer particles: The effects of various one-base mismatches on the duplex stability
    Symposium Series 2002, Vol. 5, pp. 342–343 [Abstract]
    Published online 2016-01-25 20:50:31
  • Erkki J. Nurminen, Jorma K. Mattinen and Harri Lönnberg
    Protolytic and nucleophilic role of phosphoramidite method promoters
    Symposium Series 2002, Vol. 5, pp. 129–134 [Abstract]
    Published online 2016-01-25 20:39:16
  • Satu Mikkola, Ulla Kaukinen, Izabella Zagorowska and Harri Lönnberg
    The cleavage of RNA phosphodiester bonds by metal ions
    Symposium Series 2002, Vol. 5, pp. 121–128 [Abstract]
    Published online 2016-01-25 20:39:11
  • Päivi Poijärvi and Harri Lönnberg
    Biodegradable phosphate protections of oligonucleotides
    Symposium Series 2005, Vol. 7, pp. 457–459 [Abstract]
    Published online 2015-11-08 11:58:11
  • Teija Niittymäki and Harri Lönnberg
    Sequence-selective cleavage of oligoribonucleotides
    Symposium Series 2005, Vol. 7, pp. 443–444 [Abstract]
    Published online 2015-11-08 11:57:44
  • Anu Kiviniemi, Petri Heinonen and Harri Lönnberg
    Synthesis of pentaerythritol-derived mass tags
    Symposium Series 2005, Vol. 7, pp. 413–414 [Abstract]
    Published online 2015-11-08 11:56:51
  • Kaisa Ketomäki and Harri Lönnberg
    Selective oligonucleotide probes for detection of point mutations
    Symposium Series 2005, Vol. 7, pp. 407–408 [Abstract]
    Published online 2015-11-08 11:56:41
  • Pasi Virta, Johanna Katajisto and Harri Lönnberg
    On-support oximation: A convenient method for solid-supported conjugation of oligonucleotides
    Symposium Series 2005, Vol. 7, pp. 265–267 [Abstract]
    Published online 2015-11-08 11:53:37
  • Mikko Ora, Anu Kiviniemi, Tuomas Lönnberg, Sami Virtanen and Harri Lönnberg
    Phosphodiester cleavage of diribonucleoside 3',3'-monophosphates: Rate acceleration by the 2'-hydroxyl and 2'-amino function, implications to ribozyme action
    Symposium Series 2005, Vol. 7, pp. 261–263 [Abstract]
    Published online 2015-11-08 11:53:33
  • Ulla Pentikäinen, Mikael Peräkylä and Harri Lönnberg
    The effect of base sequence on the hydrolytic stability of RNA phosphodiester bonds
    Symposium Series 2005, Vol. 7, pp. 259–260 [Abstract]
    Published online 2015-11-08 11:53:27
  • Kaisa Ketomäki, Päivi-Poijärvi Virta, Qi Wang and Harri Lönnberg
    Base moiety selectivity in cleavage of short oligonucleotides by di- and trinuclear Zn(II) complexes of azacrown-derived ligands
    Symposium Series 2008, Vol. 10, pp. 437–438 [Abstract]
    Published online 2015-10-30 18:44:32
  • Teija Niittymäki, Pasi Virta, Kaisa Ketomäki and Harri Lönnberg
    Di(azacrown) conjugates of 2'-O-methyl oligoribonucleotides as sequence-selective artificial ribonucleases
    Symposium Series 2008, Vol. 10, pp. 378–379 [Abstract]
    Published online 2015-10-30 18:42:41
  • Tuomas Karskela and Harri Lönnberg
    A facile solid-phase synthesis of 5,1',5'-trisubstituted 2,4'-biimidazoles
    Symposium Series 2008, Vol. 10, pp. 372–373 [Abstract]
    Published online 2015-10-30 18:42:24
  • Marika Karskela, Pasi Virta, Melina Malinen, Arto Urtti and Harri Lönnberg
    Synthesis and cellular uptake of fluorescently labeled multivalent hyaluronan disaccharide conjugates of oligonucleotides
    Symposium Series 2008, Vol. 10, pp. 369–371 [Abstract]
    Published online 2015-10-30 18:42:20
  • Pasi Virta
    Aminoglycoside conjugated 2'-O-methyl oligoribonucleotides: solid phase synthesis and artificial nuclease activity
    Symposium Series 2008, Vol. 10, pp. 150–154 [Abstract]
    Published online 2015-10-30 18:36:36
  • Qi Wang, Attila Jancsó, Teija Niittymäki, Päivi Poijärvi-Virta, Kaisa Ketomäki, Pasi Virta, Ewelina Leino, István Szilágyi, Satu Mikkola, Tamás Gajda and Harri Lönnberg
    Base and sequence selective cleavage of RNA phosphodiester bonds by Zn(II) azacrown chelates
    Symposium Series 2008, Vol. 10, pp. 63–70 [Abstract]
    Published online 2015-10-30 18:35:17
  • Teija Niittymäki, Ekaterina Burakova, Anna Leisvuori, Pasi Virta and Harri Lönnberg
    Effect of a uracil specific binding for the nuclease activity of bis(azacrown)conjugated 2'-O-methyl oligoribonucleotides
    Symposium Series 2011, Vol. 12, pp. 411–412 [Abstract]
    Published online 2015-08-20 10:20:54
  • Anu Kiviniemi, Pasi Virta and Harri Lönnberg
    Click conjugation of 4'-C-modified oligonucleotides
    Symposium Series 2011, Vol. 12, pp. 361–363 [Abstract]
    Published online 2015-08-20 10:19:06
  • Anu Kiviniemi and Pasi Virta
    Invasion of 2'-O-methyl oligoribonucleotides and their aminoglycoside conjugates to a 19F labelled HIV-1 TAR model
    Symposium Series 2011, Vol. 12, pp. 259–263 [Abstract]
    Published online 2015-08-20 10:10:46
  • Emilia Kiuru, Mikko Ora, Leonid Beigelman, Lawrence Blatt and Harri Lönnberg
    On the feasibility of an esterase-dependent pro-drug strategy for 2-5A
    Symposium Series 2011, Vol. 12, pp. 184–188 [Abstract]
    Published online 2015-08-20 10:00:37
  • Vyacheslav Kungurtsev, Pasi Virta and Harri Lönnberg
    Solution-phase synthesis of short oligo-2’-deoxyribonucleotides by using clustered nucleosides as a soluble support
    Symposium Series 2014, Vol. 14, pp. 312–313 [Abstract]
    Published online 2015-07-06 23:06:24
  • Tuomas Karskela*, Karel D. Klika and Harri Lönnberg
    Synthesis of 7-substituted 3-β-D-ribofuranosyl-3H-imidazo[2,1-i]purines
    2011, Vol. 76, Issue 8, pp. 1043–1054 [Abstract]
  • Tuomas Lönnberg, Šárka Králíková, Ivan Rosenberg and Harri Lönnberg*
    Kinetics and Mechanisms for the Isomerization of Internucleosidic 3'-O-P-CH2-5' and 3'-O-P-CH(OH)-5' Linkages to Their 2',5'-Counterparts
    2006, Vol. 71, Issue 6, pp. 859–870 [Abstract]
  • Alicja Stachelska*, Zbigniew J. Wieczorek, Janusz Stępiński, Marzena Jankowska-Anyszka, Harri Lönnberg and Edward Darżynkiewicz
    Kinetics of the Imidazolium Ring-Opening of mRNA 5'-cap Analogs in Aqueous Alkali
    2006, Vol. 71, Issue 4, pp. 567–578 [Abstract]
  • Andrei Guzaev, Harri Salo, Alex Azhayev and Harri Lönnberg
    Synthesis of oligonucleotide analogues by using phosphoramidite reagents derived from 2,2-bis(hydroxymethyl)malonates
    1996, Vol. 61, Special Issue, pp. S226–S229 [Abstract]
  • Harri Salo, Andrei Guzaev, Alex Azhayev and Harri Lönnberg
    Disulfide tethered solid supports for oligonucleotide synthesis: Preparation and a comparative study on the resistance to ammonolysis
    1996, Vol. 61, Special Issue, pp. S110–S111 [Abstract]
  • Harri Hakala, Pia Heinonen, Antti Iitia and Harri Lönnberg
    Covalent immobilization of oligonucleotides to microparticles. Quantitation of hybridization by time-resolved fluorescence detection on a single particle
    1996, Vol. 61, Special Issue, pp. S107–S109 [Abstract]
  • Mohamed Elzagheid, Alex Azhayev, Mikko Oivanen and Harri Lönnberg
    Synthesis of bis(3'-deoxyuridin-3'-yl) disulfide
    1996, Vol. 61, Special Issue, pp. S42–S44 [Abstract]
  • Satu Kuusela, Andrei Guzaev and Harri Lönnberg
    Zn2+ promoted hydrolysis of oligonucleotides
    1996, Vol. 61, Special Issue, pp. S30–S32 [Abstract]
  • Mikko Oivanen, Jaana Varila, Teemu Hankamaki, Leo H. Koole and Harri Lönnberg
    Hydrolysis and methanolysis of the phenyl ester of thymidine 3',5'-cyclic monophosphate: pH-dependent competition between PO and CO bond ruptures
    1996, Vol. 61, Special Issue, pp. S26–S29 [Abstract]
  • Mikko Oivanen, Mikko Ora and Harri Lönnberg
    The "thio effect" on the hydrolysis and transesterification of ribonucleoside phosphoesters
    1996, Vol. 61, Special Issue, pp. S1–S4 [Abstract]
  • Sergei N. Mikhailov, Ekaterina V. Efimtseva, Sergei V. Meshkov and Harri Lönnberg
    Novel dioxolane analogues of 2',3'-dideoxynucleosides
    1993, Vol. 58, Special Issue, pp. S68–S70 [Abstract]
  • Harri Lönnberg
    Migration of hydrogen phosphate, monoalkyl phosphate, dialkyl phosphate and alkyl phosphonate groups between the 2'- and 3'-hydroxyl functions of ribonucleosides and their analogs
    1993, Vol. 58, Special Issue, pp. S9–S13 [Abstract]
  • Janusz Stępiński, Lidia Grabowska, Edward Darżynkiewicz, Andrzej Temeriusz, Ryszard Stolarski, Stanley M. Tahara, David Shugar, Pia Järvinen and Harri Lönnberg
    Synthesis, conformation and hydrolytic stability of modified mRNA 5'-cap structures: P1,P3-dinucleoside triphosphates derived from guanosine and acyclic analogues of 7-methyl-, N2,7-dimethyl- and N2,N2,7-trimethylguanosines
    1990, Vol. 55, Special Issue, pp. S117–S120 [Abstract]
  • Mikko Oivanen, Tuula Viinamäki, Sergei Zavgorodny, Michael Polianski, Alex Azhayev, Arthur Van Aerschot, Piet Herdewijn and Harri Lönnberg
    Hydrolytic stability of potential antiviral nucleoside analogues: 3'-Substituted 2',3'-dideoxy- and 2',3'-didehydro-2',3'-dideoxyribonucleosides
    1990, Vol. 55, Special Issue, pp. S17–S20 [Abstract]
  • Jari Hovinen and Harri Lönnberg
    Kinetics and mechanism for acid-catalyzed opening of the imidazole ring of 6-unsubstituted purine nucleosides and their acyclic analogues
    1990, Vol. 55, Special Issue, pp. S9–S12 [Abstract]
  • Zbigniew Wieczorek, Edward Darżynkiewicz, Janusz Stępiński and Harri Lönnberg
    Fluorescence studies on P1,P3-dinucleoside triphosphates related to mRNA cap: Acidity and intramolecular stacking
    1990, Vol. 55, Issue 11, pp. 2765–2768 [Abstract]