Collection Symposium Series 2011, 12, 163-166
https://doi.org/10.1135/css201112163
Published online 2015-08-20 10:00:06

New strategies in synthesis of acyclic nucleoside phosphonate prodrugs

Marcela Krečmerová, Tomáš Tichý, Jiří Blažek and Karel Pomeisl

Individual author index pages


Other CCCC articles of these authors

  • Marcela Krečmerová, Miloš Buděšínský and Antonín Holý
    Synthesis of optically pure N6-alkyl derivatives of (2R)-3-(adenin-9-yl)-2-hydroxypropanoic acid and related compounds
    Symposium Series 2002, Vol. 5, pp. 358–360 [Abstract]
    Published online 2016-01-25 20:50:59
  • Karel Pomeisl, Ivan Votruba, Antonín Ho and Radek Pohl
    Pyrimidine 1-[2-(phosphonomethoxy)propyl] derivatives: Their syntheses and utilization as potent inhibitors of thymidine phosphorylase (PD-ECGF) from SD-lymphoma
    Symposium Series 2005, Vol. 7, pp. 291–295 [Abstract]
    Published online 2015-11-08 11:54:12
  • Marcela Krečmerová and Antonín Holý
    Synthesis of C-5 substituted HPMPC (cidofovir) derivatives
    Symposium Series 2005, Vol. 7, pp. 287–290 [Abstract]
    Published online 2015-11-08 11:54:07
  • Martin Dračínský, Marcela Krečmerová and Antonín Holý
    Study of chemical stability of antivirally active 5-azacytosine acyclic nucleoside phosphonates using NMR spectroscopy
    Symposium Series 2008, Vol. 10, pp. 338–340 [Abstract]
    Published online 2015-10-30 18:41:11
  • Jiří Blažek, Antonín Holý, Petra Lipovová, Zita Purkrtová and Blanka Králová
    Analogs of pyrimidin-2-one nucleosides and their enzymatic galactosylation
    Symposium Series 2008, Vol. 10, pp. 322–324 [Abstract]
    Published online 2015-10-30 18:40:37
  • Karel Pomeisl, Antonín Holý, Ivan Votruba, Radim Nencka and Radek Pohl
    Facile syntheses of pyrimidine acyclic nucleoside phosphonates and their potential evaluation for biomedical applications
    Symposium Series 2008, Vol. 10, pp. 201–205 [Abstract]
    Published online 2015-10-30 18:37:39
  • Marcela Krečmerová, Antonín Holý, Alois Pískala, Graciela Andrei, Robert Snoeck, Jan Balzarini and Erik De Clercq
    New antiviral agent, 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-5-azacytosine: esters and base-modified derivatives
    Symposium Series 2008, Vol. 10, pp. 196–200 [Abstract]
    Published online 2015-10-30 18:37:33
  • Tomáš Tichý, Graciela Andrei, Martin Dračínský, Antonín Holý, Jan Balzarini, Robert Snoeck and Marcela Krečmerová
    New amphiphilic prodrugs of adefovir and cidofovir
    Symposium Series 2011, Vol. 12, pp. 477–479 [Abstract]
    Published online 2015-08-20 10:25:04
  • Karel Pomeisl, Antonín Holý and Marcela Krečmerová
    Use of 1,3-dioxolanes in the syntheses of α-branched alkyl and aryl N-9-[2-(phosphonomethoxy)ethyl]purines
    Symposium Series 2011, Vol. 12, pp. 438–440 [Abstract]
    Published online 2015-08-20 10:23:40
  • David Mařák, Miroslav Otmar, Martin Dračínský and Marcela Krečmerová
    Nucleosides containing 8-aza-7,9-dideazaxanthine
    Symposium Series 2011, Vol. 12, pp. 383–385 [Abstract]
    Published online 2015-08-20 10:19:50
  • Marcela Krečmerová, Antonín Holý, Dana Hocková, Martin Dračínský, Dianne T. Keough and Luke W. Guddat
    9-[2-Hydroxy-3-(phosphonomethoxy)propyl] ("iso-HPMP") derivatives of purine bases and their side-chain modified analogues: synthesis and antimalarial activity
    Symposium Series 2011, Vol. 12, pp. 381–382 [Abstract]
    Published online 2015-08-20 10:19:45
  • Lucie Janská, Jiří Blažek, David Mařák, Miroslav Otmar and Marcela Krečmerová
    Chemical synthesis of prodrugs derived from 5,6-dihydro-5-azacytosine and its nucleosides using vinyl esters
    Symposium Series 2011, Vol. 12, pp. 349–350 [Abstract]
    Published online 2015-08-20 10:18:34
  • Jiří Blažek, Martin M. Kaiser, Marie Zarevúcka, Blanka Králová and Marcela Krečmerová
    Enzymatic synthesis of ester prodrugs of DHPA and related compounds by lipases
    Symposium Series 2011, Vol. 12, pp. 307–309 [Abstract]
    Published online 2015-08-20 10:11:55
  • Dana Hocková, Antonín Holý, Michal Česnek, Ondřej Baszczyňski, Tomáš Tichý, Marcela Krečmerová, Zlatko Janeba, Tina S. Skinner-Adams, Lieve Naesens, Dianne T. Keoughd, John de Jersey and Luke W. Guddat
    Acyclic nucleoside phosphonates as inhibitors of hypoxanthine-guanine-xanthine phosphoribosyltransferase: new anti-malarial chemotherapy leads
    Symposium Series 2011, Vol. 12, pp. 171–174 [Abstract]
    Published online 2015-08-20 10:00:19
  • Melissa Williams, Ivan S. Krylov, Valeria M. Zakharova, Michaela Serpi, Larryn W. Peterson, Marcela Krečmerová, Boris A. Kashemirov and Charles E. McKenna
    Cyclic and acyclic phosphonate tyrosine ester prodrugs of acyclic nucleoside phosphonates
    Symposium Series 2011, Vol. 12, pp. 167–170 [Abstract]
    Published online 2015-08-20 10:00:12
  • Tomáš Tichý, Karel Pomeisl, Marcela Krečmerová and Charles E. McKenna
    Tyrosine-based prodrugs of acyclic nucleoside phosphonates
    Symposium Series 2014, Vol. 14, pp. 126–128 [Abstract]
    Published online 2015-07-06 22:58:53
  • Marcela Krečmerová*, Antonín Holý and Milena Masojídková
    Pyrimidine Acyclic Nucleotide Analogues with Aromatic Substituents in C-5 Position
    2007, Vol. 72, Issue 7, pp. 927–951 [Abstract]
  • Karel Pomeisl*, Ivan Votruba, Antonín Holý and Radek Pohl
    Syntheses of Base and Side-Chain Modified Pyrimidine 1-[2-(Phosphonomethoxy)propyl] Derivatives as Potent Inhibitors of Thymidine Phosphorylase (PD-ECGF) from SD-Lymphoma
    2006, Vol. 71, Issue 4, pp. 595–624 [Abstract]
  • Marcela Krečmerová*, Milena Masojídková and Antonín Holý
    Preparation of C-5 Substituted Cidofovir Derivatives
    2006, Vol. 71, Issue 4, pp. 579–594 [Abstract]
  • Karel Pomeisl*, Radek Pohl, Antonín Holý and Ivan Votruba
    Simple Transformation of Thymine 1-[3-Hydroxy-2-(phosphonomethoxy)propyl] Derivatives to Their 1-[3-Fluoro-2-(phosphonomethoxy)propyl] Counterparts
    2005, Vol. 70, Issue 9, pp. 1465–1481 [Abstract]
  • Marcela Krečmerová*, Milena Masojídková and Antonín Holý
    Synthesis of N9- and N7-[2-Hydroxy-3-(phosphonomethoxy)propyl] Derivatives of N6-Substituted Adenines, 2,6-Diaminopurines and Related Compounds
    2004, Vol. 69, Issue 10, pp. 1889–1913 [Abstract]
  • Marcela Krečmerová*, Miloš Buděšínský, Milena Masojídková and Antonín Holý
    Synthesis of Optically Active N6-Alkyl Derivatives of (R)-3-(Adenin-9-yl)-2-hydroxypropanoic Acid and Related Compounds
    2003, Vol. 68, Issue 5, pp. 931–950 [Abstract]
  • Marcela Krečmerová, Hubert Hřebabecký and Antonín Holý
    Synthesis of 5-Phenylcytosine Nucleoside Derivatives
    1996, Vol. 61, Issue 4, pp. 645–655 [Abstract]
  • Marcela Krečmerová, Hubert Hřebabecký and Antonín Holý
    Preparation of 5-Benzyluracil and 5-Benzylcytosine Nucleosides as Potential Inhibitors of Uridine Phosphorylase
    1996, Vol. 61, Issue 4, pp. 627–644 [Abstract]
  • Marcela Krečmerová, Hubert Hřebabecký, Milena Masojídková and Antonín Holý
    2',3'-Dideoxy- and 3'-Azido-2',3'-dideoxynucleosides of 5-Phenyl-2(1H)-pyrimidinone. Preparation of 2',3'-Dideoxypentofuranoses
    1996, Vol. 61, Issue 3, pp. 478–488 [Abstract]
  • Marcela Krečmerová, Hubert Hřebabecký, Milena Masojídková and Antonín Holý
    Synthesis of 5-Phenyl-2(1H)-pyrimidinone Nucleosides
    1996, Vol. 61, Issue 3, pp. 458–477 [Abstract]
  • Marcela Krečmerová, Antonín Holý and Milena Masojídková
    Synthesis of 3-(4-Pyridinyl)-, 3-(2-Chloro-4-pyridinyl)- and 3-(2-Amino-4-pyridinyl)propoxymethanephosphonic Acid
    1995, Vol. 60, Issue 4, pp. 670–680 [Abstract]
  • Marcela Krečmerová and Antonín Holý
    Preparation of Phosphonomethyl Ethers Derived from 2-Phenylethanol and Its Amino Derivatives
    1995, Vol. 60, Issue 4, pp. 659–669 [Abstract]
  • Marcela Krečmerová, Hubert Hřebabecký, Milena Masojídková and Antonín Holý
    Preparation of Purine 2'-Deoxy-5'-O-phosphonomethylnucleosides and 2'-Deoxy-3'-O-phosphonomethylnucleosides
    1993, Vol. 58, Issue 2, pp. 421–434 [Abstract]
  • Marcela Krečmerová, Hubert Hřebabecký and Antonín Holý
    5'-O-Phosphonylmethyl derivatives of 2'-deoxynucleosides
    1990, Vol. 55, Special Issue, pp. S121–S124 [Abstract]
  • Marcela Krečmerová, Hubert Hřebabecký and Antonín Holý
    Synthesis of 5'-O-phosphonomethyl derivatives of pyrimidine 2'-deoxynucleosides
    1990, Vol. 55, Issue 10, pp. 2521–2536 [Abstract]
  • Marcela Krečmerová, Miloslav Černý, Miloš Buděšínský and Antonín Holý
    Utilization of 1,6-anhydrohexoses for the preparation of some aliphatic adenosine analogs
    1989, Vol. 54, Issue 10, pp. 2753–2766 [Abstract]