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2005, Volume 7, Collection Symposium Series
- ISSN 0010-0765 printed
- ISSN 1212-6950 electronic
2005, Volume 7, Collection Symposium Series
Conference
Title | XIIIth Symposium on Chemistry of Nucleic Acid Components |
Location | Špindlerův Mlýn |
Date |
3 Sep 2005
–
9 Sep 2005
|
Articles
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pp. 1-20
Frank Seela, Xiaohua Peng, Hong Li, Padmaja Chittepu, Khalil I. Shaikh, Junlin He, Yang He and Igor Mikhailopulo
Modified DNA: From synthesis to molecular recognition
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pp. 21-26
Damian Ittig, Dorte Renneberg, David Vonlanthen, Samuel Luisier and Christian J. Leumann
Oligonucleotide analogues: From supramolecular principles to biological properties
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pp. 27-28
Patrick J. Hrdlicka, B. Ravindra Babu, Mads D. Sørensen, Niels Harrit and Jesper Wengel
Ångström-scale chemical engineering: Multilabeled 2'-amino-LNA probes for nucleic acid detection in homogenous fluorescence assays
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pp. 29-37
Piet Herdewijn
The Diels–Alder cyclo addition as key reaction for the synthesis of cyclohexenyl nucleosides
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pp. 39-46
Wojciech Dabkowski and Jan Michalski
A novel approach to synthesis of nucleotides and their structural analogues via tricoordinate phosphorus reagents
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pp. 47-55
Hans-Achim Wagenknecht
Electron transfer chemistry in synthetically modified DNA
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pp. 57-64
Isao Saito, Yoshio Saito, Akimitsu Okamoto, Tomohisa Ichiba, Keiichiro Kanatani and Kazuki Tainaka
Design of highly selective fluorescent nucleobases for SNP typing: Base-discriminating fluorescent (BDF) probe
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pp. 65-73
Eduard K. Liebler, Katrin B. Lorenz, Björn Dietrich, Katja Bensmann, Britta Eickmann and Ulf Diederichsen
DNA binding of peptides derived from natural products or proteins and bending of DNA double strands
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pp. 75-76
J. Chattopadhyaya
Evidences for the electrostatic promoted modulation of the chemical reactivity of nucleobases and phosphates in RNA
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pp. 77-84
Aaron M. Leconte and Floyd E. Romesberg
Efforts towards expansion of the genetic alphabet
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pp. 85-85
David C. K. Chu
Dioxolane nucleosides: Chemistry and biology
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pp. 87-93
Gloria Cristalli, Diego Dal Ben, Catia Lambertucci, Floriana R. Portino, Sara Taffi, Sauro Vittori and Rosaria Volpini
Synthesis of new P2 receptor ligands
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pp. 95-103
Karl Y. Hostetler and James R. Beadle
Orally active lipid esters of antiviral nucleoside phosphonates
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pp. 105-113
Chris Meier, Christian Ducho, Henning Jessen and Jan Balzarini
Esterase-cleavable cycloSal-pronucleotides – the trapping concept
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pp. 115-122
Shigeki Sasaki, Fumi Nagatsugi, Monsur Ali, Sayaka Mori and Shizuka Nakayama
Molecular design for DNA hybridization-promoted reactions with high efficiency and selectivity
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pp. 123-126
Andreas Marx
Modulation of DNA polymerase function for DNA diagnostics
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pp. 127-132
Sujiet Puthenveetil, Landon Whitby, Olena Maydanovych, Brittany Haudenschild and Peter A. Beal
Modified RNA for the study of enzymes involved in RNA editing, the innate immune response and RNA interference
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pp. 133-142
Agnieszka Bzowska, Katarzyna Stępniak, Monika Olasek, Maciej Długosz, Beata Wielgus-Kutrowska, Jan Antosiewicz, Antonín Holý, Gertraud Koellner, Albrecht Stroh, Grzegorz Raszewski, Thomas Steiner and Joachim Frank
Attempts to differentiate subunits of trimeric and hexameric purine nucleoside phosphorylases by crystal structure and solution studies using purine bases, modified purine nucleosides, acyclonucleosides and their phosphonate analogues
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pp. 143-147
Gaelle Deglane, Said Abes, Thibaut Michel, Alain Laurent, Magali Naval, Camille Martinand-Mari, Paul Prevot, Eric Vives, Ian Robbins, Ivan Barvik, Jr, Bernard Lebleu, Françoise Debart and Jean-Jacques Vasseur
Combining a cationic phosphoramidate backbone and α-anomeric nucleosides provides oligonucleotides with improved hybridization and cell uptake properties
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pp. 149-152
Fernando Ferreira, Albert Meyer, Jean-Jacques Vasseur and François Morvan
Universal and reusable solide support thanks to a H-phosphonate diester linkage for the synthesis of single or multiple oligonucleotides
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pp. 153-157
Ivan Rosenberg, Ivan Barvik, Miloš Buděšínský, Petr Kočalka, Šárka Králíková, Radek Liboska, Ondřej Pačes, Ondřej Páv, Magdalena Petrová, Radek Pohl, Martina Pressová, Dominik Rejman, Ivan Votruba and Zdeněk Točík
Nucleoside phosphonic acids and related oligonucleotides: Structural diversity vs biological properties
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pp. 159-163
Dominik Rejman, Petr Kočalka, Radek Pohl and Ivan Rosenberg
Synthesis of 4'-N pyrrolidine nucleosides, nucleotides, and oligonucleotides
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pp. 165-166
Radek Pohl, Dominik Rejman, Petr Kočalka and Ivan Rosenberg
Pyrrolidine nucleotide analogues – conformation study
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pp. 167-171
Piotr Guga, Anna Maciaszek and Wojciech J. Stec
Oxathiaphospholane approach to the synthesis of oligodeoxyribonucleotides containing stereodefined internucleotide phosphoroselenoate function
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pp. 173-175
Irene M. Lagoja
"Split-nucleosides" – a novel class of purine bioisosters
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pp. 177-181
Jerzy Boryski and Grzegorz Framski
Mechanism of ribosylation of adenine
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pp. 183-187
Michał Sobkowski, Jadwiga Jankowska, Jacek Stawinski and Adam Kraszewski
Stereochemistry of internucleotide bond formation by the H-phosphonate method. 2. Transesterification of aryl ribonucleoside H-phosphonate diesters with alcohols
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pp. 189-193
Johan Nilsson, Thomas Szabo, Gaston Lavén, Martin Kullberg, Adam Kraszewski and Jacek Stawinski
Developing synthetic methods for bioactive phosphorus compounds. A progress report
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pp. 195-199
Gaston Lavén and Jacek Stawinski
Synthetic studies on the preparation of dinucleoside phenylphosphonates and phenylphosphonothioates via palladium(0) catalysed cross-coupling
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pp. 201-205
Renata Hiresova, Liubov Putilova, Martin Kullberg and Jacek Stawinski
Determination of absolute configuration of nucleoside 3'-H-phosphonothioate monoesters via stereochemical correlation analysis
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pp. 207-211
Martin Kullberg and Jacek Stawinski
Reactions of H-phosphonate and H-phosphonothioate diesters with carbonyl compounds. 31P NMR studies
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pp. 213-216
Michal Hocek and Dana Hocková
Regioselective cross-coupling reactions in the synthesis of multisubstituted purine bases and nucleosides
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pp. 217-220
Petr Čapek and Michal Hocek
Synthesis of (purin-6-yl)amino acids
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pp. 221-224
Peter Šilhár, Radek Pohl, Ivan Votruba and Michal Hocek
Synthesis and transformations of 6-(hydroxymethyl)purines
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pp. 225-228
Pavol Cekan and Snorri Th. Sigurdsson
Spin labeled nucleic acids for EPR spectroscopic study of DNA and RNA structure and function
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pp. 229-232
Glenn A. Burley, Johannes Gierlich, Mohammad Reza Mofid, David M. Hammond and Thomas Carell
New labelling strategies for the sensitive detection of nucleic acids
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pp. 233-237
Gavin O'Mahony, Eleonor Ehrman and Morten Grøtli
Adenosine-based fluorosides containing a novel heterocyclic ring system
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pp. 239-243
Agnieszka B. Olejniczak, Błażej Wojtczak, Marzena Przepiórkiewicz, Marek Kwiatkowski and Zbigniew J. Lesnikowski
Nucleosides and their phosphates modified with dicarba-closo-dodecaborane (–C2B10H11) at 2'-position
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pp. 245-248
Marie-Paule Teulade-Fichou, Markus Kaiser, Matthieu Sainlos, Sophie Bombard, David Monchaud, Clémence Jacquelin, Candide Hounsou and Rémy Lartia
Customized fused aromatics for structural recognition of nucleic acids
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pp. 249-251
Michal Česnek and Antonín Holý
Biological activity of selected guanidinopurines
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pp. 253-257
Matthaios Varaggoulis, Antonio Salgado and Thanasis Gimisis
Synthesis and stability of parabanic acid nucleosides
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pp. 259-260
Ulla Pentikäinen, Mikael Peräkylä and Harri Lönnberg
The effect of base sequence on the hydrolytic stability of RNA phosphodiester bonds
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pp. 261-263
Mikko Ora, Anu Kiviniemi, Tuomas Lönnberg, Sami Virtanen and Harri Lönnberg
Phosphodiester cleavage of diribonucleoside 3',3'-monophosphates: Rate acceleration by the 2'-hydroxyl and 2'-amino function, implications to ribozyme action
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pp. 265-267
Pasi Virta, Johanna Katajisto and Harri Lönnberg
On-support oximation: A convenient method for solid-supported conjugation of oligonucleotides
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pp. 269-270
Tuomas Lönnberg, Johanna Kiiski, Jonna Korhonen and Satu Mikkola
The 2'-OH group as a hydrogen bond donor in the reactions of group I introns
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pp. 271-275
Aleksandra Živković and Joachim W. Engels
Fluorinated benzenes and benzimidazoles as RNA analogues
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pp. 277-278
Jan Štambaský, Pavel Kočovský and Michal Hocek
Towards a novel approach to C-nucleosides
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pp. 279-282
Pavel Turek, Michal Hocek and Martin Kotora
Cocyclotrimerization of 6-alkynylpurines with diynes as a novel approach to biologically active 6-arylpurines
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pp. 283-285
Miroslav Otmar, Milena Masojídková and Antonín Holý
Acyclic nucleoside phosphonates containing O-substituted hydroxypyridineamines and diamines as nucleobases
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pp. 287-290
Marcela Krečmerová and Antonín Holý
Synthesis of C-5 substituted HPMPC (cidofovir) derivatives
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pp. 291-295
Karel Pomeisl, Ivan Votruba, Antonín Ho and Radek Pohl
Pyrimidine 1-[2-(phosphonomethoxy)propyl] derivatives: Their syntheses and utilization as potent inhibitors of thymidine phosphorylase (PD-ECGF) from SD-lymphoma
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pp. 297-300
Rosaria Volpini, Catia Lambertucci, Sara Taffi, Sauro Vittori, Karl-Norbert Klotz and Gloria Cristalli
A3 adenosine receptors: Synthesis and biological evaluation of new potent and selective ligands
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pp. 301-305
Tomasz Goslinski, Grazyna Wenska and Bozenna Golankiewicz
A novel series of strongly fluorescent tricyclic analogues of acyclovir resulting from spontaneous oxidation of some of their 7-[4-(benzhydryl)phenyl]-6-(4-R-phenyl) derivatives
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pp. 307-311
Stephen L. Atkin, Sylvain Barrier, Stephen T. Beckett, Tom Brown, Grahame Mackenzie and Leigh Madden
Towards the use of sporopollenin in drug delivery: Efficient encapsulation of oligonucleotides
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pp. 313-314
Ineke Van Daele, Hélene Munier-Lehmann and Serge Van Calenbergh
Exploring high affinity inhibitors of M. tuberculosis thymidiylate kinase
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pp. 315-318
Kathleen Too, Daniel M. Brown and David Loakes
Mutagenic nucleoside analogues for use as antivirals by error catastrophe
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pp. 319-327
B.-K. Chun, J. L. Clark, J. Du, P. A. Furman, A. E. Hassan, L. Hollecker, T. McBrayer, M. E. Otto, K. W. Pankiewicz, S. E. Patterson, S. Rachakonda, R. F. Schinazi, L. J. Stuyver, P. W. Wang, K. A. Watanabe and T. Whitaker
5',9-Anhydro-3-(β-D-ribofuranosyl)purine nucleoside analogues as potential anti-HCV agents
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pp. 329-332
Pooran Chand, Ajit K. Ghosh, Pravin L. Kotian, Tsu-Hsing Lin, Yahya El-Kattan, Minwan Wu, Vadlakonda S. Kumar and Yarlagadda S. Babu
Synthesis of (2S,3S,4R,5R)-2-(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-5-(hydroxymethyl)-3-methylpyrrolidine-3,4-diol, an analog of potent HCV inhibitor
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pp. 333-337
Sergey N. Mikhailov, Ekaterina V. Efimtseva, Alexandra A. Shelkunova, Jef Rozenski, Gert Emmerechts, Arthur Van Aerschot and Piet Herdewijn
Chemical incorporation of minor tRNA component O-β-D-ribofuranosyl-(1''-2')-adenosine-5''-phosphate into oligoribonucleotides
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pp. 339-342
Donata Pluskota-Karwatka, Magdalena Bruszyńska and Leif Kronberg
Identification of an adduct formed in the reaction of malonaldehyde-glyoxal with adenosine
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pp. 343-346
Thibaut Michel, Didier Gasparutto, Christine Saint-Pierre and Jean Cadet
Synthesis of O6-hydroxyethyl-2'-deoxyguanosine adducts containing oligonucleotides for the evaluation of their mutagenic features
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pp. 347-350
Sadie D. Osborne and Jane A. Grasby
Investigations into substrate analogues for Fen-1
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pp. 351-354
John A. Brazier, Julie Fisher and Richard Cosstick
3'-Phosphorothiolate linkages within multistranded helical structures
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pp. 355-359
Marcin Kalek, Jacek Jemielity, Ewa Grudzien, Joanna Zuberek, Zbigniew M. Darzynkiewicz, Elzbieta Bojarska, Janusz Stępiński, Ryszard Stolarski, Richard E. Davis, Robert E. Rhoads and Edward Darżynkiewicz
Synthesis and biochemical properties of the novel, enzymatically stable mRNA cap analogues with versatile potential applications
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pp. 361-365
Jacek Jemielity, Janusz Stępiński, Joanna Zuberek, Ewa Grudzien, Magdalena Lewdorowicz, Ryszard Stolarski, Robert E. Rhoads and Edward Darżynkiewicz
Dinucleotide analogues of the mRNA cap that enhance translational efficiency
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pp. 367-371
Gabriela D. Ivanova, Andrey A. Arzumanov, B. Ravindra Babu, Neerja Karla, David Sweedler, Leo Beigelman, Jesper Wengel and Michael J. Gait
Inhibition of HIV-1 Tat-dependent trans-activation by steric block oligonucleotide analogues containing amino modifications
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pp. 373-374
Miroslav Hájek, Naděžda Matulová, Ivan Votruba, Antonín Holý and Eva Tloušťová
Acyclic nucleoside phosphonates and human telomerase inhibition
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pp. 375-378
Barbara Nawrot, Kinga Widera, Marzena Wojcik, Katarzyna Cieslinska, Beata Rebowska and Wojciech J. Stec
Phosphorothioate modified DNAzymes
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pp. 379-380
Andrey Semenyuk, András Földesi, Tommy Johansson, Camilla Estmer Nilsson, Mathias Brännvall, Leif Kirsebum and Marek Kwiatkowski
Reliable method for RNA synthesis using t-butyldithiomethyl (DTM) group for the 2'-hydroxyl protection
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pp. 381-383
Ludmila A. Alexandrova, Maxim V. Jasko and Marina K. Kukhanova
Fluorescent esters of triphosphoric acid – effective substrates of terminal deoxynucleotidil transferase
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pp. 385-386
Jelena Božilović, Jan W. Bats and Joachim W. Engels
Synthesis and crystal structures of fluorinated indols as RNA analogues
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pp. 387-388
Šárka Chalupová and Antonín Holý
Synthesis of N4-substituted derivatives of (S)-1-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine (HPMPC, Cidofovir, Vistide©)
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pp. 389-391
Guido H. Clever and Thomas Carell
Assembly of a highly DNA-duplex stabilizing salen-metallo-base pair
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pp. 393-394
Liesbet Cosyn, Kenneth A. Jacobson and Serge Van Calenbergh
2-(1,2,3-Triazol-1-yl) N6-CH3-substituted adenosine derivatives: Highly potent and selective A3 receptor ligands
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pp. 395-396
Petra Doláková, Milena Masojídková and Antonín Holý
Synthesis and properties of chiral open-ring acyclic nucleoside bisphosphonates
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pp. 397-399
Alexia Chollat-Namy, Didier Gasparutto, Jean Cadet and Alain Favier
Nucleic acid biosensors for real-time monitoring of DNA repair activites by FRET
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pp. 401-402
Imrich Géci, Vyacheslav V. Filichev and Erik B. Pedersen
Synthesis of twisted intercalating nucleic acids (TINA) possesing acridine derivatives
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pp. 403-404
Kateřina Hořejší, Radek Pohl and Antonín Holý
Tricyclic etheno analogs of purines derived from 2-amino-6-chloropurine
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pp. 405-406
Mariola Kozłowska and Zygmunt Kazimierczuk
Synthesis of 2'-deoxyribonucleosides by the Mitsunobu reaction
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pp. 407-408
Kaisa Ketomäki and Harri Lönnberg
Selective oligonucleotide probes for detection of point mutations
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pp. 409-411
Anastasia L. Khandazhinskaya, Elena A. Shirokova, Eugene A. Kataev, Sergey L. Deev, Eugene N. Ulomsky, Tatyana S. Shestakova, Vladimir L. Rusinov, Oleg N. Chupakhin, Eugene F. Belanov and Marina K. Kukhanova
A new group of nucleoside mimics: Chemical synthesis and antiviral properties
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pp. 413-414
Anu Kiviniemi, Petri Heinonen and Harri Lönnberg
Synthesis of pentaerythritol-derived mass tags
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pp. 415-416
Petr Kočalka, Markéta Rinnová, Václav Vaněk, Dominik Rejman, Ivan Votruba, Ivana Tomečková, Šárka Králíková, Magdalena Petrová, Ondřej Páv, Radek Pohl, Miloš Buděšínský, Radek Liboska, Zdeněk Točík and Ivan Rosenberg
Novel nucleoside phosphonic acids-based inhibitors of thymidine phosphorylase
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pp. 417-419
Joanna Kowalska, Magdalena Lewdorowicz, Joanna Zuberek, Elzbieta Bojarska, Zbigniew M. Darzynkiewicz, Ewa Grudzien, Richard E. Davis, Robert E. Rhoads, Janusz Stępiński, Ryszard Stolarski, Edward Darżynkiewicz and Jacek Jemielity
Synthesis and properties of phosphorothioate 5' mRNA cap dinucleotides
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pp. 421-422
Šárka Králíková, Miloš Buděšínský, Radek Liboska, Ondřej Páv and Ivan Rosenberg
2',5'-Linked oligo-3'-deoxynucleotide chimeras with chiral α-hydroxyphosphonate internucleotide linkage: Improvement of hybridisation selectivity toward RNA?
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pp. 423-424
Martin Kuchař and Michal Hocek
Synthesis of purines bearing functionalized C-substituents by nucleophilic additions to 6-ethynyl- or 6-vinylpurines
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pp. 425-427
Irina V. Kulikova, Ivan S. Varizhuk, Georgii V. Bobkov, Ekaterina V. Efimtseva and Sergey N. Mikhailov
Effective anomerisation of 2'-deoxyadenosine and thymidine derivatives
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pp. 429-431
Peter Leonard, Xin Ming, Anup M. Jawalekar, Wilma Thür, Dieter Heindl and Frank Seela
Universal bases: Base pairing and duplex stability of oligonucleotides containing pyrrolo[2,3-d]pyrimidines and 5-nitroindole nucleosides
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pp. 433-435
Magdalena Lewdorowicz, Jacek Jemielity, Ryszard Kierzek, Michal Shapira, Janusz Stępiński, Ryszard Stolarski and Edward Darżynkiewicz
Solid-supported synthesis of 5' mRNA cap-4 from trypanosomatides
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pp. 437-438
Radek Liboska, Ondřej Páv and Ivan Rosenberg
Monomers for novel phosphonate oligonucleotides, potential RNase L inhibitors
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pp. 439-440
François Morvan, Aude-Emmanuelle Navarro, Cécile Dueymes, Ilaria Adamo, Andreas Schoenberger, Albert Meyer, Fritz Link, Meinolf Lange, Jean-Louis Imbach and Jean-Jacques Vasseur
Solution phase synthesis of oligonucleotides by the phosphoramidite method using solid supported reagents
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pp. 441-442
Radim Nencka, Ivan Votruba, Hubert Hřebabecký, Eva Tloušťová, Květa Horská, Milena Masojídková and Antonín Holý
Design and synthesis of 5,6-disubstituted uracil derivatives as potent inhibitors of thymidine phosphorylase
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pp. 443-444
Teija Niittymäki and Harri Lönnberg
Sequence-selective cleavage of oligoribonucleotides
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pp. 445-446
Petr Novák, Michal Hocek and Martin Kotora
Synthesis of C-arylribosides by catalytic [2+2+2]-cyclotrimerization reaction
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pp. 447-448
Ondřej Pačes and Ivan Rosenberg
Isopolar, isosteric 4'-substituted 2',5'-oligoadenylates as potential RNase L activators
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pp. 449-451
Dimitris Panagopoulos, Antonio Salgado and Thanasis Gimisis
Preparation of 2'-deoxy nucleosides of cyanuric acid for their inclusion in DNA oligonucleotides
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pp. 453-454
Ondřej Páv, Eva Protivínská, Jiří Jiráček and Ivan Rosenberg
ABEI-labeled 2-5A: A way to chemiluminescent imaging of RNase L binding process
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pp. 455-456
Agnieszka J. Pawłowicz, Tony Munter, Karel D. Klika and Leif Kronberg
Reaction of acrolein with N9-ethyladenine – formation of adduct containing new six-membered fused rings
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pp. 457-459
Päivi Poijärvi and Harri Lönnberg
Biodegradable phosphate protections of oligonucleotides
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pp. 461-462
Michal Šála, Hubert Hřebabecký, Milena Masojídková and Antonín Holý
Synthesis of novel racemic conformationally locked carbocyclic nucleosides
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pp. 463-464
Markéta Schinkmanová, Ivan Votruba and Antonín Holý
N6-methyl-AMP hydrolase activates N6-substituted purine ANPs
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pp. 465-466
Grigorii G. Sivets, Elena N. Kalinichenko and Igor A. Mikhailopulo
Synthesis of 2'-β-fluoro-substituted adenine nucleosides via pivaloyl derivatives of adenosine and 3'-deoxyadenosine
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pp. 467-469
Michał Sobkowski, Jacek Stawinski and Adam Kraszewski
A proposal of DP/LP notation for nucleotide analogues with a chiral phosphorus centre
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pp. 471-473
Damian Smuga, Iwona Fratczak and Elzbieta Sochacka
Incorporation of amino acid modified nucleosides into catalytic core of deoxyribozyme "10-23"
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pp. 475-477
Alicja Stachelska and Zbigniew Wieczorek
Alkaline hydrolysis of the imidazole moiety in the dinucleotide cap analogs – is the stacking interaction important?
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pp. 479-480
Janusz Stępiński, Remigiusz Worch, Joanna Zuberek, Elzbieta Bojarska, Jacek Jemielity, Magdalena Lewdorowicz, Ryszard Stolarski, Dorota Haber and Edward Darżynkiewicz
Synthesis and preliminary characterization of mRNA 5' cap analogues containing ribavirin
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pp. 481-482
Zdeněk Točík, Ivan Barvík, Jr., Miloš Buděšínský and Ivan Rosenberg
Isosteric phosphonate 3'-O-P-CH2-O-4'C internucleotide linkage: Attempts to get more data on its stereochemistry
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pp. 483-484
Václav Vaněk, Miloš Buděšínský and Ivan Rosenberg
The synthesis of monomers for prolinol-based oligonucleotides
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pp. 485-486
Milan Vrabel, Ivan Rosenberg and Michal Hocek
Synthesis of modified nucleosides and oligonucleotides bearing bipyridine or phenanthroline ligands
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pp. 487-488
Silvie Vrbovská and Antonín Holý
Novel type of bis-phosphonate congeners of acyclic nucleoside phosphonates
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pp. 489-491
Borys Kierdaszuk and Jacek Wierzchowski
8-Azapurines as substrates for the E. coli purine nucleoside phosphorylase – II (xanthosine phosphorylase): Does the ribosylation always go to the aza-purine N(9)?
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pp. 493-494
Gerda Wittel, Ping Gu and Joachim W. Engels
Synthesis and activity of C-analogues for immune stimulating CpG-oligodeoxynucleotides