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Collection Symposium Series 2005, 7, 143-147
https://doi.org/10.1135/css200507143
Published online 2015-11-08 11:51:27

Combining a cationic phosphoramidate backbone and α-anomeric nucleosides provides oligonucleotides with improved hybridization and cell uptake properties

Gaelle Deglane, Said Abes, Thibaut Michel, Alain Laurent, Magali Naval, Camille Martinand-Mari, Paul Prevot, Eric Vives, Ian Robbins, Ivan Barvik, Jr, Bernard Lebleu, Françoise Debart and Jean-Jacques Vasseur

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  • Wojtyniak Melissa, Schmidtgall Boris, Kirsch Philine, Ducho Christian: Towards Zwitterionic Oligonucleotides with Improved Properties: the NAA/LNA‐Gapmer Approach. ChemBioChem 2020, 21, 3234. <https://doi.org/10.1002/cbic.202000450>
  • Meng Melissa, Ducho Christian: Oligonucleotide analogues with cationic backbone linkages. Beilstein J. Org. Chem. 2018, 14, 1293. <https://doi.org/10.3762/bjoc.14.111>
  • Morvan François, Debart Françoise, Vasseur Jean‐Jacques: From Anionic to Cationic α‐Anomeric Oligodeoxynucleotides. Chemistry & Biodiversity 2010, 7, 494. <https://doi.org/10.1002/cbdv.200900220>